Mubritinib

Product Name: Mubritinib
CAS No.: 366017-09-6
Chemical Name: Mubritinib
Synonyms: CS-522;TAK 165;MUBRITINIB;TAK165;TAK-165;Mubritinib(TAK 165);Mubritinib USP/EP/BP;(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;(E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1H-1,2,3-Triazole, 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-
CBNumber: CB21011746
Molecular Formula: C25H23F3N4O2
Formula Weight: 468.47
MOL File: 366017-09-6.mol

More

Less

Mubritinib Property

Melting point:: 158.0 to 162.0 °C
Boiling point:: 620.9±65.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO : 50 mg/mL (106.73 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
pka: 1.45±0.10(Predicted)
form: powder to crystal
color: White to Gray to Brown

More

Less

Safety

HS Code: 2934.99.4400

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1312
Product name: Mubritinib
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $74.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1312
Product name: Mubritinib
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $289
Updated: 2024/03/01

TCI Chemical

Product number: M3058
Product name: Mubritinib
Purity: >98.0%(HPLC)
Packaging: 25mg
Price: $185
Updated: 2024/03/01

TCI Chemical

Product number: M3058
Product name: Mubritinib
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $552
Updated: 2024/03/01

Cayman Chemical

Product number: 12096
Product name: Mubritinib
Purity: ≥98%
Packaging: 5mg
Price: $39
Updated: 2024/03/01

More

Less

Mubritinib Chemical Properties,Usage,Production

Uses

Treatment of cancer.

Uses

Mubritinib is used in selective targeting of CTNNB1-, KRAS-or MYC-driven human cancer cell growth by combinations of existing drugs

Biological Activity

Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .

storage

Store at +4°C

Mubritinib Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Mubritinib Suppliers

Americas 1 China 114 Europe 2 Germany 1 India 2 Japan 1 United Kingdom 4 United States 21 Global 146

Guangzhou Tomums Life Science Co., Ltd.

Tel: 020-31155029 18902330969
Fax: 020-31155029
Email: sales@tomums.cn
Country: China
ProdList: 4696
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

More

Less

View Lastest Price from Mubritinib manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Mubritinib 366017-09-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Mubritinib 366017-09-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Dideu Industries Group Limited

Product: Mubritinib 366017-09-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-06

366017-09-6, MubritinibRelated Search:

2-Methoxyethanol tert-Butylchlorodiphenylsilane Anisole Nizatidine Dasatinib monohydrate PHENYL VALERATE VINYL PROPIONATE 1,4-Adamantandiol 4-Methoxyphenylacetone (Trifluoromethoxy)benzene Lapatinib Gefitinib Imatinib Pralmorelin Sunitinib Phenylhydrazine Vinyl ester resin Trifluoromethyl

MUBRITINIB

1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole

TAK 165

Mubritinib(TAK 165)

CS-522

TAK165;TAK-165

(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole

1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165)

Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole

(E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole

1H-1,2,3-Triazole, 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-

Mubritinib USP/EP/BP

366017-09-6

C25H23F3N4O2

Inhibitors