ChemicalBook > CAS DataBase List > 5-Chloroindole

5-Chloroindole

Product Name
5-Chloroindole
CAS No.
17422-32-1
Chemical Name
5-Chloroindole
Synonyms
5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;6-Chloroindole99%;5-CHLOROINDOLE99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
CBNumber
CB2126773
Molecular Formula
C8H6ClN
Formula Weight
151.59
MOL File
17422-32-1.mol
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5-Chloroindole Property

Melting point:
69-71 °C (lit.)
Boiling point:
130 °C / 0.4mmHg
Density 
1.1976 (rough estimate)
refractive index 
1.5437 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in alcohol.
form 
Crystalline Powder
pka
16.09±0.30(Predicted)
color 
White to slightly grayish-green
BRN 
2651
InChIKey
MYTGFBZJLDLWQG-UHFFFAOYSA-N
CAS DataBase Reference
17422-32-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
22-24/25-36-26-37/39
RIDADR 
2811
WGK Germany 
3
F 
10
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C47604
Product name
5-Chloroindole
Purity
98%
Packaging
1g
Price
$44.58
Updated
2024/03/01
Sigma-Aldrich
Product number
C47604
Product name
5-Chloroindole
Purity
98%
Packaging
5g
Price
$80.4
Updated
2024/03/01
TCI Chemical
Product number
C1107
Product name
5-Chloroindole
Purity
>98.0%(GC)
Packaging
5g
Price
$86
Updated
2024/03/01
TCI Chemical
Product number
C1107
Product name
5-Chloroindole
Purity
>98.0%(GC)
Packaging
25g
Price
$254
Updated
2024/03/01
Usbiological
Product number
006333
Product name
5-Chloroindole
Packaging
2.5g
Price
$446
Updated
2021/12/16
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5-Chloroindole Chemical Properties,Usage,Production

Chemical Properties

White to slightly greyish-green crystalline powder

Uses

5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.

Uses

5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 29, p. 1625, 1992 DOI: 10.1002/jhet.5570290644
The Journal of Organic Chemistry, 44, p. 578, 1979 DOI: 10.1021/jo01318a021

General Description

5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT3 receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.

Purification Methods

It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]

5-Chloroindole Preparation Products And Raw materials

Raw materials

5-Chloro-2-nitrotoluene Diethyl oxalate Ferrous sulfate heptahydrate Potassium

Preparation Products

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View Lastest Price from 5-Chloroindole manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
5-Chloroindole 17422-32-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-29
Henan Aochuang Chemical Co.,Ltd.
Product
5-Chloroindole 17422-32-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Chemwill Asia Co.,Ltd.
Product
5-Chloroindole in stock Factory 17422-32-1
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 largest production capacity Factory
Release date
2019-04-03

17422-32-1, 5-ChloroindoleRelated Search:

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