Azlocillin sodium
- Product Name
- Azlocillin sodium
- CAS No.
- 37091-65-9
- Chemical Name
- Azlocillin sodium
- Synonyms
- AZLOCILLIN SODIUM SALT;securopen;Prestwick_48;sodium azlocillin;AZLOCILLIN SODIUM;AZLOCILLINE SODIUM;Aloxicillin sodium;monosodiumazlocillin;D-alpha-([Imidazolidin;Azlocillin sodium, >=95%
- CBNumber
- CB2128131
- Molecular Formula
- C20H22N5NaO6S
- Formula Weight
- 483.47
- MOL File
- 37091-65-9.mol
Azlocillin sodium Property
- Melting point:
- >199oC (dec.)
- Flash point:
- >110°(230°F)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- H2O: soluble50mg/mL
- form
- powder
- color
- White to Off-White
- Water Solubility
- Freely soluble in water
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 37091-65-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 42/43
- Safety Statements
- 36
- WGK Germany
- 3
- RTECS
- XH9250000
- Toxicity
- mouse,LD50,intramuscular,15420mg/kg (15420mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: TREMORBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX),Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. Vol. 32, Pg. 453, 1987.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- A7926
- Product name
- Azlocillin sodium salt
- Packaging
- 1g
- Price
- $149
- Updated
- 2024/03/01
- Product number
- A7926
- Product name
- Azlocillin sodium salt
- Packaging
- 5g
- Price
- $521
- Updated
- 2023/06/20
- Product number
- J66895
- Product name
- Azlocillin sodium, 90%
- Packaging
- 10g
- Price
- $343
- Updated
- 2021/12/16
- Product number
- J66895
- Product name
- Azlocillin sodium, 90%
- Packaging
- 1g
- Price
- $37.1
- Updated
- 2021/12/16
- Product number
- 18424
- Product name
- Azlocillin (sodium salt)
- Purity
- ≥95%
- Packaging
- 250mg
- Price
- $32
- Updated
- 2024/03/01
Azlocillin sodium Chemical Properties,Usage,Production
Originator
Securopen,Bayer,W. Germany,1977
Uses
Antibacterial;Bacterial transpeptidase inhibitor
Uses
Azlocillin sodium is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques.
Definition
ChEBI: Azlocillin sodium is an organic sodium salt. It contains an azlocillin(1-).
Manufacturing Process
3.8 parts by weight of D-(-)-α-[(imidazolidin-2-on-1-yl)carbonylamino]phenylacetic acid were dissolved in 65 parts by volume of dichloromethane. 2.7 parts by weight of 1-methyl-2-chloro-δ1-pyrrolinium chloride were added, and after cooling to -10°C 2.0 parts by volume of triethylamine were added gradually. This reaction mixture was then stirred for one hour at -5°C (mixture A). 4.0 parts by weight of 6-aminopenicillanic acid in 80 parts by volume of dichloromethane were treated with 4.4 parts by volume of triethylamine and 4.0 parts by weight of anhydrous sodium sulfate and then stirred for two hours at room temperature. After filtration, the solution was cooled to -20°C and combined with the mixture A. The reaction mixture was left to reach 0°C of its own accord, and was then stirred for a further hour at 0°C. The solvent was removed in a rotary evaporator, the residue was dissolved in water, and the solution was covered with a layer of ethyl acetate and acidified with dilute hydrochloric acid at 0° to 5°C, while stirring, until pH 1.5 was reached. The organic phase was then separated off, washed with water, dried over magnesium sulfate while cooling, and filtered, and after dilution with an equal amount of ether the sodium salt of the penicillin was precipitated from the filtrate by adding a solution of sodium 2-ethylcaproate dissolved in ether containing methanol. Yield: 1.3 parts by weight.
brand name
Azlin (Bayer).
Therapeutic Function
Antibacterial
Azlocillin sodium Preparation Products And Raw materials
Raw materials
Preparation Products
Azlocillin sodium Suppliers
- Tel
- 027-83989310 18627915365
- Fax
- 027-83989310
- 2658488909@qq.com
- Country
- China
- ProdList
- 1297
- Advantage
- 58
- Tel
- 021-50182298 021-50180596
- Fax
- +86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2210
- Advantage
- 55
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15848
- Advantage
- 69
- Tel
- 021-54306202 13764082696;
- info@hanhongsci.com
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- 0712-0712-2580635 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8849
- Advantage
- 52
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 4548
- Advantage
- 62
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4647
- Advantage
- 58
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4941
- Advantage
- 60
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12338
- Advantage
- 58
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7553
- Advantage
- 61
View Lastest Price from Azlocillin sodium manufacturers
- Product
- Azlocillin sodium salt 37091-65-9
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99.912%
- Supply Ability
- 10ton
- Release date
- 2024-04-22
- Product
- Azlocillin sodium 37091-65-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.0%
- Supply Ability
- 20 tons
- Release date
- 2023-07-13
- Product
- Azlocillin sodium 37091-65-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-06-30