Azlocillin sodium

Product Name: Azlocillin sodium
CAS No.: 37091-65-9
Chemical Name: Azlocillin sodium
Synonyms: AZLOCILLIN SODIUM SALT;securopen;Prestwick_48;sodium azlocillin;AZLOCILLIN SODIUM;AZLOCILLINE SODIUM;Aloxicillin sodium;monosodiumazlocillin;D-alpha-([Imidazolidin;Azlocillin sodium, >=95%
CBNumber: CB2128131
Molecular Formula: C20H22N5NaO6S
Formula Weight: 483.47
MOL File: 37091-65-9.mol

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Azlocillin sodium Property

Melting point:: >199oC (dec.)
Flash point:: >110°(230°F)
storage temp.: Inert atmosphere,2-8°C
solubility: H2O: soluble50mg/mL
form: powder
color: White to Off-White
Water Solubility: Freely soluble in water
Stability:: Hygroscopic
CAS DataBase Reference: 37091-65-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 42/43
Safety Statements: 36
WGK Germany: 3
RTECS: XH9250000
Toxicity: mouse,LD50,intramuscular,15420mg/kg (15420mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: TREMORBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX),Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. Vol. 32, Pg. 453, 1987.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A7926
Product name: Azlocillin sodium salt
Packaging: 1g
Price: $149
Updated: 2024/03/01

Sigma-Aldrich

Product number: A7926
Product name: Azlocillin sodium salt
Packaging: 5g
Price: $521
Updated: 2023/06/20

Alfa Aesar

Product number: J66895
Product name: Azlocillin sodium, 90%
Packaging: 10g
Price: $343
Updated: 2021/12/16

Alfa Aesar

Product number: J66895
Product name: Azlocillin sodium, 90%
Packaging: 1g
Price: $37.1
Updated: 2021/12/16

Cayman Chemical

Product number: 18424
Product name: Azlocillin (sodium salt)
Purity: ≥95%
Packaging: 250mg
Price: $32
Updated: 2024/03/01

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Azlocillin sodium Chemical Properties,Usage,Production

Originator

Securopen,Bayer,W. Germany,1977

Uses

Antibacterial;Bacterial transpeptidase inhibitor

Uses

Azlocillin sodium is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques.

Definition

ChEBI: Azlocillin sodium is an organic sodium salt. It contains an azlocillin(1-).

Manufacturing Process

3.8 parts by weight of D-(-)-α-[(imidazolidin-2-on-1-yl)carbonylamino]phenylacetic acid were dissolved in 65 parts by volume of dichloromethane. 2.7 parts by weight of 1-methyl-2-chloro-δ1-pyrrolinium chloride were added, and after cooling to -10°C 2.0 parts by volume of triethylamine were added gradually. This reaction mixture was then stirred for one hour at -5°C (mixture A). 4.0 parts by weight of 6-aminopenicillanic acid in 80 parts by volume of dichloromethane were treated with 4.4 parts by volume of triethylamine and 4.0 parts by weight of anhydrous sodium sulfate and then stirred for two hours at room temperature. After filtration, the solution was cooled to -20°C and combined with the mixture A. The reaction mixture was left to reach 0°C of its own accord, and was then stirred for a further hour at 0°C. The solvent was removed in a rotary evaporator, the residue was dissolved in water, and the solution was covered with a layer of ethyl acetate and acidified with dilute hydrochloric acid at 0° to 5°C, while stirring, until pH 1.5 was reached. The organic phase was then separated off, washed with water, dried over magnesium sulfate while cooling, and filtered, and after dilution with an equal amount of ether the sodium salt of the penicillin was precipitated from the filtrate by adding a solution of sodium 2-ethylcaproate dissolved in ether containing methanol. Yield: 1.3 parts by weight.

brand name

Azlin (Bayer).

Therapeutic Function

Antibacterial

Azlocillin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Azlocillin sodium Suppliers

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View Lastest Price from Azlocillin sodium manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Azlocillin Sodium 37091-65-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-21

Hangzhou Hyper Chemicals Limited

Product: Azlocillin sodium 37091-65-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥90%
Supply Ability: 150kg
Release date: 2024-08-08

Hangzhou ICH Biofarm Co., Ltd

Product: Azlocillin sodium 37091-65-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.0%
Supply Ability: 20 tons
Release date: 2023-07-13

37091-65-9, Azlocillin sodiumRelated Search:

Sodium gluconate Diclofenac sodium Acetylacetone Dimethyl ether Diethylstilbestrol Dimethyl sulfide Dimethyl fumarate Azlocillin N-ACETYL-L-TYROSINE ETHYL ESTER Sodium formate Sodium bicarbonate N,N-Dimethylformamide Acetylferrocene Sodium carbonate Ampicillin sodium Ampicillin Dimethyl phthalate Penicillin G

sodium [2S-[2alpha,5alpha,6beta(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Sterile Azlocillin sodium

AZLOCILLINE SODIUM

d-α-([imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin

sodium azlocillin

sodium [2s-[2a,5a,6b(s*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-,monosodiumsalt,(

5-alpha,6-beta(s*)))-2s-(2-alph

monosodiumazlocillin

securopen

sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2S)-1-oxo-2-[[oxo-(2-oxo-1-imidazolidinyl)methyl]amino]-2-phenylethyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(2S,5β)-3,3-Dimethyl-7-oxo-6α-[[(R)-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt

D-alpha-([Imidazolidin

Prestwick_48

Azlocillin sodium salt,D-α-([Imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin

Azlocillin Sodium (200 mg)

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, sodium salt (1:1), (2S,5R,6R)-

Azlocillin sodium, >=95%

Sodium [2S-[2a,5a,6b(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxy

D-ALPHA-[(IMIDAZOLIDIN-2-ON-1-YL)-CARBONYLAMINO]BENZYLPENICILLIN

D-A-([IMIDAZOLIDIN-2-ON-1-YL]CARBONYLAMINO)BENZYLPENICILLIN

AZLOCILLIN SODIUM

AZLOCILLIN SODIUM SALT

3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-((R)-2-(2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Azlocillin sodium USP/EP/BP

Azlocillin Sodium Salt (1.0mg/ml in DMSO)

AzlocillinSodiumQ: What is AzlocillinSodium Q: What is the CAS Number of AzlocillinSodium Q: What is the storage condition of AzlocillinSodium Q: What are the applications of AzlocillinSodium

Aloxicillin sodium

Phenylephrine Impurity 105-d3

37091-65-9

C20H22N5NaO6S

C20H23N5O6SNa

C20H22N5O6SNa

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37091-65-9