ChemicalBook > CAS DataBase List > 2-Amino-5-fluorobenzoic acid

2-Amino-5-fluorobenzoic acid

Product Name
2-Amino-5-fluorobenzoic acid
CAS No.
446-08-2
Chemical Name
2-Amino-5-fluorobenzoic acid
Synonyms
5-FLUOROANTHRANILIC ACID;5-FAA;NSC 513308;AURORA KA-5382;BUTTPARK 19\04-54;RARECHEM AL BO 2236;5-Fluoranthranilsure;5-fluoroanthranilicaci;Zavegepant Impurity 74;2-Amino-5-fluorobenzoic
CBNumber
CB2136554
Molecular Formula
C7H6FNO2
Formula Weight
155.13
MOL File
446-08-2.mol
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2-Amino-5-fluorobenzoic acid Property

Melting point:
181-183 °C(lit.)
Boiling point:
223.67°C (rough estimate)
Density 
1.3021 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
1.86±0.10(Predicted)
form 
Fine Crystalline Powder
color 
Light yellow to light brown
BRN 
2803664
InChI
InChI=1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey
FPQMGQZTBWIHDN-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(F)=CC=C1N
CAS DataBase Reference
446-08-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
367982
Product name
2-Amino-5-fluorobenzoic acid
Purity
97%
Packaging
1g
Price
$43.56
Updated
2024/03/01
Sigma-Aldrich
Product number
367982
Product name
2-Amino-5-fluorobenzoic acid
Purity
97%
Packaging
10g
Price
$459
Updated
2024/03/01
TCI Chemical
Product number
F0396
Product name
5-Fluoroanthranilic Acid
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$46
Updated
2024/03/01
TCI Chemical
Product number
F0396
Product name
5-Fluoroanthranilic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$179
Updated
2024/03/01
Alfa Aesar
Product number
B21458
Product name
2-Amino-5-fluorobenzoic acid, 98+%
Packaging
1g
Price
$54.65
Updated
2024/03/01
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2-Amino-5-fluorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Used in the synthesis of styrylquinazolinones which are potential anticancer agents.

Uses

2-Amino-5-fluorobenzoic acid is used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It can be used for the selection of tryptophan auxotroophs.

Definition

ChEBI: An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine.

reaction suitability

reaction type: solution phase peptide synthesis

2-Amino-5-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-5-fluorobenzoic acid Suppliers

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View Lastest Price from 2-Amino-5-fluorobenzoic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Amino-5-fluorobenzoic acid 446-08-2
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-5-fluorobenzoic acid 446-08-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08
Hebei Miaobian Biotechnology Co., Ltd
Product
2-Amino-5-fluorobenzoic acid 446-08-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99.99
Supply Ability
10Ton
Release date
2021-03-12

446-08-2, 2-Amino-5-fluorobenzoic acidRelated Search:

Glycine Urethane Folic acid Citric acid 4-Fluorobenzoic acid 6-Aminocaproic acid 4-Aminobenzoic acid POLYURETHANE Methyl anthranilate EPA ALTRENOGEST Ascoric Acid Anthranilic acid 2-Amino-4,5-difluorobenzoic acid 2-Amino-6-fluorobenzoic acid 97%,2-AMINO-6-FLUOROBENZOIC ACID (6-FLUOROANTHRANILIC ACID),2-Amino-6-fluorobenzoic acid, 98% (6-Fluoroanthranilic acid) 2,3,4,5-TETRAFLUORO-6-NITROBENZOIC ACID 2-AMINO-3,4,5,6-TETRAFLUOROBENZOIC ACID 4,5-Difluoro-2-nitrobenzoic acid

  • 2-AMINO-5-FLUOROBENZOIC ACID
  • RARECHEM AL BO 2236
  • 2-AMino-5-fluorobenzoic acid, 97% 1GR
  • NSC 513308
  • 2-aMino-5-fluorobenzoic aicd
  • 2-Amino-5-fluorobenzoic acid 98%
  • 5-Fluoroanthranilic acid, 2-Carboxy-4-fluoroaniline
  • Anthranilic acid, 5-fluoro-
  • Benzoic acid, 2-amino-5-fluoro-
  • BUTTPARK 19\04-54
  • AURORA KA-5382
  • 5-FluoroanthranilicAcid/2-Amino-5-FluorobenzoicAcid
  • 2-Amino-5-fluoroBenzoicacid97.
  • 2-Amino-5-fluorobenzoic Acid, 5-FAA
  • 2-Amino-5-fluorobenzoic
  • 5-FLUOROANTHRANILIC ACID
  • 5-FAA
  • 2-Amino-5-fluorobenzoic acid 97.5%
  • 2-AMINO-5-FLUOROBENZOIC ACID 99+%
  • 5-FLUOROANTHRANILIC ACID 98+%
  • 5-Fluoroanthanilic acid
  • 2-Amino-5-fluorobenzoic acid (5-Fluoroanthranilic acid)
  • 2-Amino-5-fluorobenzoic acid, 98+%
  • 2-Amino-5-fluorobenzoic Acid See: F587750
  • 5-FluoroanthranilicAcid&gt
  • 5-Fluoranthranilsure
  • 2-Amino-5-fluorobenzoic acid,0.98
  • 5-fluoroanthranilicaci
  • Zavegepant Impurity 74
  • 446-08-2
  • 446-8-2
  • 466-08-2
  • CARBOXYLIC ACID
  • Aromatic Amino Acids
  • Peptide Synthesis
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Aromatics
  • 5-FOA
  • Bases & Related Reagents
  • Nucleotides
  • Benzoic acid Series
  • Nucleotides and Nucleosides
  • Aromatics Compounds
  • Benzoic acid series
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Amines
  • FINE Chemical & INTERMEDIATES
  • Fluorobenzene
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Carboxylic Acids
  • Phenyls & Phenyl-Het
  • Benzoic acid
  • Fluorin-contained Benzoic acid series
  • Fluorine series