ChemicalBook > CAS DataBase List > Cyclosporin C

Cyclosporin C

Product Name
Cyclosporin C
CAS No.
59787-61-0
Chemical Name
Cyclosporin C
Synonyms
CL246;CS-2546;CS-2545;WF-3484;CYCLOSPORIN C;Thr2-cyclosporine;Cyclosporin C, >=95%;Cyclosporine IMpurity-C;Cyclosporin Impurity C;Cyclosporine Impurity 3
CBNumber
CB2153074
Molecular Formula
C62H111N11O13
Formula Weight
1218.61
MOL File
59787-61-0.mol
More
Less

Cyclosporin C Property

Melting point:
144-1460C
alpha 
D20 -255° (c = 0.5 in chloroform); D20 -182° (c = 0.5 in methanol)
Boiling point:
1316.0±65.0 °C(Predicted)
Density 
1.033±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO: ≥10mg/mL
pka
13.06±0.70(Predicted)
form 
Colorless to off-white crystalline solid.
color 
White to Off-White
InChIKey
JTOKYIBTLUQVQV-PCACHRFWSA-N
CAS DataBase Reference
59787-61-0
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H350May cause cancer

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
29152
Product name
Cyclosporin C
Packaging
5mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
29152
Product name
Cyclosporin C
Packaging
25mg
Price
$330
Updated
2024/03/01
Cayman Chemical
Product number
29152
Product name
Cyclosporin C
Packaging
1mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
29152
Product name
Cyclosporin C
Packaging
10mg
Price
$183
Updated
2024/03/01
TRC
Product number
C988905
Product name
Cyclosporin C
Packaging
5mg
Price
$265
Updated
2021/12/16
More
Less

Cyclosporin C Chemical Properties,Usage,Production

Description

Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. It is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs = 0.1-5 μg/ml). Cyclosporin C (15 μg/ml) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%. It inhibits lymphocyte proliferation induced by the mitogens concanavalin A (ConA; ), phytohemagglutinin L (PHA), and pokeweed mitogen (PWM), as well as proliferation induced by alloantigen in mixed lymphocyte culture when used at a concentration of 100 ng/ml. Cyclosporin C (100 ng/ml) inhibits the local graft versus host (GVH) reaction in mice receiving splenocyte grafts.

Chemical Properties

White Solid

Uses

A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cyclosporin C is a minor analogue of the cyclosporin complex produced by a number of fungal species, including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin C possesses immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A.

storage

+4°C

Cyclosporin C Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Cyclosporin C Suppliers

CHEMICAL LAND21
Tel
--
Fax
--
Email
sales21@chemicalland21.com
Country
South Korea
ProdList
6303
Advantage
74
More
Less

View Lastest Price from Cyclosporin C manufacturers

Jiangsu Nata Opto-electronic Material Co.,Ltd.
Product
Cyclosporin C 59787-61-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
95%
Supply Ability
1kg
Release date
2023-05-25
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Thr2-Cyclosporine 59787-61-0
Price
US $299.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2021-12-20
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Thr2-Cyclosporine
Price
US $16.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
2kgs
Release date
2021-12-30

59787-61-0, Cyclosporin CRelated Search:


  • CYCLOSPORIN C
  • Cyclosporine C/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
  • 30-(1-hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriaconta
  • CS-2545
  • CS-2546
  • cyclo-[MeBmt-Thr-Sar-MeLeu-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal]
  • Cyclosporine EP Impurity C
  • Thr2-cyclosporine
  • Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
  • (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Thr-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
  • WF-3484
  • 7-L-Threoninecyclosporin A
  • Cyclosporine IMpurity-C
  • 7-L-Threoninecyclosporin A, WF 3484
  • 7-Threonine-cyclosporin A
  • Cyclosporin C, >=95%
  • CL246
  • Cyclosporin Impurity C
  • Cyclosporin Impurity 3(Cyclosporin C)
  • Cyclosporin A, 7-L-threonine-
  • Cyclosporine Impurity 3
  • (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-Hydroxy-2-methylhex-4-en-1-yl)-30-((R)-1-hydroxyethyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
  • (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,1
  • (3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
  • Cyclosporin C, EvoPure?
  • (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-30-[(1R)-1-hydroxyethyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
  • 59787-61-0
  • 69787-61-0
  • 59767-61-0
  • C62H111N11O13
  • Intermediates & Fine Chemicals
  • Peptides
  • Pharmaceuticals
  • ACTIVE PHARMACEUTICAL INGREDIENTS