PANCREATIC POLYPEPTIDE (BOVINE)

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PANCREATIC POLYPEPTIDE (BOVINE)

Product Name: PANCREATIC POLYPEPTIDE (BOVINE)
CAS No.: 179986-89-1
Chemical Name: PANCREATIC POLYPEPTIDE (BOVINE)
Synonyms: PANCREATIC POLYPEPTIDE (BOVINE);Pancreatic polypeptide (pig),6-L-glutamic acid-;H-Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
CBNumber: CB2160531
Formula Weight: 0
MOL File: Mol file

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PANCREATIC POLYPEPTIDE (BOVINE) Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0044801
Product name: PancreaticPolypeptide,bovine
Packaging: 500ug
Price: $210
Updated: 2021/12/16

ChemScene

Product number: CS-0044801
Product name: PancreaticPolypeptide,bovine
Packaging: 1mg
Price: $330
Updated: 2021/12/16

ChemScene

Product number: CS-0044801
Product name: PancreaticPolypeptide,bovine
Packaging: 5mg
Price: $1100
Updated: 2021/12/16

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PANCREATIC POLYPEPTIDE (BOVINE) Chemical Properties,Usage,Production

Biological Activity

Pancreatic Polypeptide, bovine is a linear polypeptide of 36 amino acids produced in the pancreas that inhibits pancreatic secretion induced by secretin and cholecystokinin. It is a neuropeptide (NPY) receptor agonist with high affinity for NPYR4.

in vitro

Pancreatic Polypeptide, bovine is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic Polypeptide (1 μM) does not alter proliferation in BRIN BD11 or 1.1B4 beta-cells, but reverses the decreased cell viability in BRIN BD11 cells induced by streptozotocin. Pancreatic Polypeptide (0.1 nM-1 μM) shows no effect on insulin secretion from isolated mouse islets, and does not affect the membrane potential and (Ca ²⁺ ) _i levels in BRIN BD11 cells at 1 μM. Pancreatic Polypeptide, bovine inhibits secretin- and cholecystokinin-stimulated pancreatic secretion. ¹²⁵ I-Pancreatic Polypeptide, bovine shows no specific binding to pancreatic acini.

in vivo

Pancreatic Polypeptide (25 nmol/kg bw, ip) reduces glucose-stimulated insulin concentrations but shows no effect on acute feeding behaviour in overnight fasted mice. Pancreatic Polypeptide, bovine (BPP; 40 μg/kg) inhibits CCK -33-induced pancreatic protein output during the entire bovine Pancreatic Polypeptide infusion period, but shows no effect on biliary protein output during CCK-33 or CCK-8 infusion.

PANCREATIC POLYPEPTIDE (BOVINE) Preparation Products And Raw materials

Raw materials

Preparation Products

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179986-89-1, PANCREATIC POLYPEPTIDE (BOVINE)Related Search:

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H-Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

PANCREATIC POLYPEPTIDE (BOVINE)

Pancreatic polypeptide (pig),6-L-glutamic acid-

179986-89-1

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