ChemicalBook > CAS DataBase List > PROCYANIDIN B3

PROCYANIDIN B3

Product Name: PROCYANIDIN B3
CAS No.: 23567-23-9
Chemical Name: PROCYANIDIN B3
Synonyms: RS533;RS 533;RS-533;PROCYANIDIN B3;Procyanidol B3;PROCYANIDIN B3 USP/EP/BP;procyanidin B3 from barley;CATECHIN-(4ALPHA->8)-CATECHIN;Procyanidin B3, 10 mM in DMSO;CATECHIN-(4ALPHA->8)-CATECHIN B3
CBNumber: CB2172174
Molecular Formula: C30H26O12
Formula Weight: 578.52
MOL File: 23567-23-9.mol

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PROCYANIDIN B3 Property

Melting point:: 218-219℃
Boiling point:: 955.3±65.0 °C(Predicted)
Density: 1.705
storage temp.: Sealed in dry,2-8°C
solubility: Soluble in acetone and acetonitrile
form: powder
pka: 9.29±0.60(Predicted)
color: White
InChIKey: XFZJEEAOWLFHDH-AVFWISQGSA-N
SMILES: [C@H]1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2[C@@H](C2=C3O[C@H](C4=CC=C(O)C(O)=C4)[C@@H](O)CC3=C(O)C=C2O)[C@@H]1O
CAS DataBase Reference: 23567-23-9

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29065
Product name: Procyanidin B3
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 29065
Product name: Procyanidin B3
Packaging: 10mg
Price: $330
Updated: 2024/03/01

Cayman Chemical

Product number: 29065
Product name: Procyanidin B3
Packaging: 5mg
Price: $180
Updated: 2024/03/01

Usbiological

Product number: 361861
Product name: Procyanidin B3
Packaging: 5mg
Price: $765
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP65542
Product name: Procyanidin B3
Packaging: 100ug
Price: $50
Updated: 2021/12/16

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PROCYANIDIN B3 Chemical Properties,Usage,Production

Uses

Procyanidin B3 is a natural product that acts as a specific HAT inhibitor. Procyanidin B3 is a polyphenol flavonoid dimer of (+)-catechin with diverse biological properties. Procyanidin B3 is a dimeric flavanol and an antifungal phenol extracted from Woodfordia uniflora.

Definition

ChEBI: A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarp Macho.

in vivo

Procyanidin B3 (100 mg/kg, p.o., 5 days a week for 4 weeks) prevents articular cartilage degeneration and heterotopic cartilage formation in a surgically-induced osteoarthritis mice model^[2]. Procyanidin B3 (30 mg/kg, p.o., once daily for 4 weeks) delays the development of intervertebral disc degeneration (IVDD) in a Lipopolysaccharides (HY-D1056)-induced IVDD Sprague-Dawley rats model^[2].

Animal Model:	Lipopolysaccharides (HY-D1056)-induced IVDD (intervertebral disc degeneration) Sprague-Dawley rats model
Dosage:	30 mg/kg
Administration:	Oral gavage (p.o.),once daily for 4 weeks
Result:	Prevented the loss of gelatin NP cells and structural damage of annulus fibrosus in IVDD rat model.

Animal Model:	Surgically-induced osteoarthritis mice model^[2]
Dosage:	100 mg/kg
Administration:	Oral gavage (p.o.), once daily, 5 days a week for 4 weeks
Result:	Prevented aberrant articular cartilage degeneration and heterotopic cartilage formation through suppression of the nitric oxide synthase (iNOS).

IC 50

CBP/p300; TLR4

PROCYANIDIN B3 Preparation Products And Raw materials

Raw materials

Preparation Products

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PROCYANIDIN B3 Suppliers

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View Lastest Price from PROCYANIDIN B3 manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Procyanidin B3 23567-23-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-28

Career Henan Chemical Co

Product: Procyanidin B3 23567-23-9
Price: US $2.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 100kg
Release date: 2019-12-23

23567-23-9, PROCYANIDIN B3Related Search:

Procyanidin B1 PROCYANIDIN A2 PROCYANIDIN C1 PROCYANIDIN B2(RG),(4→8)-Procyanidin B2,PROCYANIDIN B2 (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol Prodelphinidin T4 (4→6)-Procyanidin B5 PROCYANIDIN A1 PROCYANIDIN B-4 N-BUTYLISOCYANIDE Tosylmethyl isocyanide SALCOMINE TERT-BUTYL ISOCYANIDE Benzyl isocyanide METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Cupric acetylacetonate Ferric acetylacetonate

[4,8''-Biflavan]-3,3',3'',3''',4',4''',5,5'',7,7''-decol stereoisomer

Procyanidol B3

(2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-dihydroxyphenyl)-[4,8'-bichroman]-3,3',5,5',7,7'-hexaol

PROCYANIDIN B3

CATECHIN-(4ALPHA->8)-CATECHIN

CATECHIN-(4ALPHA->8)-CATECHIN B3

(2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-dihydroxyphenyl)-4,8'-bichroman-3,3',5,5',7,7'-hexol

(2R,2'R,3S,3'S,4α)-3,3',4,4'-Tetrahydro-2α,2'α-bis(3,4-dihydroxyphenyl)-4,8'-bi[2H-1-benzopyran]-3,3',5,5',7,7'-hexol

procyanidin B3 from barley

3,3',4,4'-Tetrahydro-2α,2'α-bis(3,4-dihydroxyphenyl)-4α,8'-bi[2H-1-benzopyran]-3β,3'β,5,5',7,7'-hexol

(2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-[4,8'-bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol

[4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-, (2R,2'R,3S,3'S,4S)-

PROCYANIDIN B3 USP/EP/BP

RS 533

RS533

RS-533

(2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol

Procyanidin B3, 10 mM in DMSO

(2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol

23567-23-9

Catechins & Tannins