Aminoacetonitrile hydrochloride
- Product Name
- Aminoacetonitrile hydrochloride
- CAS No.
- 6011-14-9
- Chemical Name
- Aminoacetonitrile hydrochloride
- Synonyms
- Glycinonitrile hydrochloride;e hydrochL;GlycinonitrileHCl;Aminoacetonitrile hy;AMINO ACETONITRILE HCL;Acetonitrile hydrochloride;Cyanomethylazanium chloride;cyanomethanaminium chloride;Aminoacetonitrilhydrochlorid;AMINOACETONITRILE HYDROCHLORIDE
- CBNumber
- CB2181554
- Molecular Formula
- C2H5ClN2
- Formula Weight
- 92.53
- MOL File
- 6011-14-9.mol
Aminoacetonitrile hydrochloride Property
- Melting point:
- 172-174°C
- RTECS
- MC1950000
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Methanol (Slightly, Heated), Water
- form
- Powder
- color
- White to Off-White
- Water Solubility
- Soluble in water 20°C, 1000g/L.
- Sensitive
- Hygroscopic
- Merck
- 14,412
- CAS DataBase Reference
- 6011-14-9(CAS DataBase Reference)
- EPA Substance Registry System
- Aminoacetonitrile hydrochloride (6011-14-9)
Safety
- Risk Statements
- 20/21/22-36/37/38-25
- Safety Statements
- 22-36/37-45-26
- RIDADR
- 3439
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309IF exposed or if you feel unwell:
N-Bromosuccinimide Price
- Product number
- R288616
- Product name
- AMINOACETONITRILE HYDROCHLORIDE
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $179
- Updated
- 2024/03/01
- Product number
- 041984
- Product name
- Aminoacetonitrile hydrochloride, 98+%
- Packaging
- 25g
- Price
- $82.5
- Updated
- 2024/03/01
- Product number
- A580055
- Product name
- AminoacetonitrileHydrochloride
- Packaging
- 10g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 079136
- Product name
- Aminoacetonitrile hydrochloride
- Packaging
- 1g
- Price
- $9
- Updated
- 2021/12/16
- Product number
- 079136
- Product name
- Aminoacetonitrile hydrochloride
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
Aminoacetonitrile hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White to light brown solid
Uses
Used as pharmaceutical intermediates, organic synthetic raw material transportation.
Application
Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.
Preparation
Synthesis of Aminoacetonitrile Hydrochloride by Reaction of Aminoacetonitrile with Hydrogen Chloride in Methanol: mixing the aminoacetonitrile with hydrogen chloride methanol solution, reacting at 45-50°C for 1-2 hours, cooling to below 5°C, filtering, and centrifugalizing to obtain the aminoacetonitrile hydrochloride, wherein in the hydrogen chloride methanol solution, the content of hydrogen chloride is 30-50 wt%, and the water content is less than or equal to 1%.
Preparation method of aminoacetonitrile hydrochloride
Safety Profile
An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
Purification Methods
The salt recrystallises from dilute EtOH as hygroscopic leaflets. It is best to crystallise it from absolute EtOH/Et2O (1:1) and then recrystallise it from absolute EtOH. The melting point recorded ranges from 144o to 174o. The free base has b 58o/15mm with partial decomposition. [Klages J Prakt Chem [2] 65 189 1902, Mange J Am Chem Soc 56 2197 1934, Goldberg & Kelly J Chem Soc 1371 1947, Beilstein 4 H 344, 4 I 468, 4 II 783, 4 III 1120, 4 IV 2363.]
Aminoacetonitrile hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Aminoacetonitrile hydrochloride Suppliers
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- Country
- United Kingdom
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- Advantage
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View Lastest Price from Aminoacetonitrile hydrochloride manufacturers
- Product
- Aminoacetonitrile hydrochloride 6011-14-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-21
- Product
- Aminoacetonitrile hydrochloride 6011-14-9
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-19
- Product
- Aminoacetonitrile hydrochloride 6011-14-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-15