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Aminoacetonitrile hydrochloride

Product Name
Aminoacetonitrile hydrochloride
CAS No.
6011-14-9
Chemical Name
Aminoacetonitrile hydrochloride
Synonyms
Glycinonitrile hydrochloride;e hydrochL;GlycinonitrileHCl;Aminoacetonitrile hy;AMINO ACETONITRILE HCL;Acetonitrile hydrochloride;Cyanomethylazanium chloride;cyanomethanaminium chloride;Aminoacetonitrilhydrochlorid;AMINOACETONITRILE HYDROCHLORIDE
CBNumber
CB2181554
Molecular Formula
C2H5ClN2
Formula Weight
92.53
MOL File
6011-14-9.mol
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Aminoacetonitrile hydrochloride Property

Melting point:
172-174°C
RTECS 
MC1950000
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Methanol (Slightly, Heated), Water
form 
Powder
color 
White to Off-White
Water Solubility 
Soluble in water 20°C, 1000g/L.
Sensitive 
Hygroscopic
Merck 
14,412
CAS DataBase Reference
6011-14-9(CAS DataBase Reference)
EPA Substance Registry System
Aminoacetonitrile hydrochloride (6011-14-9)
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Safety

Risk Statements 
20/21/22-36/37/38-25
Safety Statements 
22-36/37-45-26
RIDADR 
3439
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R288616
Product name
AMINOACETONITRILE HYDROCHLORIDE
Purity
AldrichCPR
Packaging
50MG
Price
$179
Updated
2024/03/01
Alfa Aesar
Product number
041984
Product name
Aminoacetonitrile hydrochloride, 98+%
Packaging
25g
Price
$82.5
Updated
2024/03/01
TRC
Product number
A580055
Product name
AminoacetonitrileHydrochloride
Packaging
10g
Price
$50
Updated
2021/12/16
Oakwood
Product number
079136
Product name
Aminoacetonitrile hydrochloride
Packaging
100g
Price
$55
Updated
2021/12/16
Oakwood
Product number
079136
Product name
Aminoacetonitrile hydrochloride
Packaging
1g
Price
$9
Updated
2021/12/16
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Aminoacetonitrile hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

Used as pharmaceutical intermediates, organic synthetic raw material transportation.

Application

Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.

Preparation

Synthesis of Aminoacetonitrile Hydrochloride by Reaction of Aminoacetonitrile with Hydrogen Chloride in Methanol: mixing the aminoacetonitrile with hydrogen chloride methanol solution, reacting at 45-50°C for 1-2 hours, cooling to below 5°C, filtering, and centrifugalizing to obtain the aminoacetonitrile hydrochloride, wherein in the hydrogen chloride methanol solution, the content of hydrogen chloride is 30-50 wt%, and the water content is less than or equal to 1%.
Preparation method of aminoacetonitrile hydrochloride

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

Purification Methods

The salt recrystallises from dilute EtOH as hygroscopic leaflets. It is best to crystallise it from absolute EtOH/Et2O (1:1) and then recrystallise it from absolute EtOH. The melting point recorded ranges from 144o to 174o. The free base has b 58o/15mm with partial decomposition. [Klages J Prakt Chem [2] 65 189 1902, Mange J Am Chem Soc 56 2197 1934, Goldberg & Kelly J Chem Soc 1371 1947, Beilstein 4 H 344, 4 I 468, 4 II 783, 4 III 1120, 4 IV 2363.]

Aminoacetonitrile hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Aminoacetonitrile hydrochloride Suppliers

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View Lastest Price from Aminoacetonitrile hydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Aminoacetonitrile hydrochloride 6011-14-9
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Chuanghai Biotechnology Co,.LTD
Product
Aminoacetonitrile hydrochloride 6011-14-9
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19
Henan Fengda Chemical Co., Ltd
Product
Aminoacetonitrile hydrochloride 6011-14-9
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-15

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