ChemicalBook > CAS DataBase List > Vanillyl ethyl ether

Vanillyl ethyl ether

Product Name: Vanillyl ethyl ether
CAS No.: 13184-86-6
Chemical Name: Vanillyl ethyl ether
Synonyms: FEMA 3815;DAIRY ENHANCER;VanilinEthylEther;ETHYL VANILLYL ETHER;VANILLYL ETHYL ETHER;Vanilla alcohol ether;Xianglan alcohol ether;13184-86-6 Vanillyl ethyl ether;4-[ETHOXYMETHYL]-2-METHOXYPHENOL;Phenol, 4-(ethoxymethyl)-2-methoxy-
CBNumber: CB2183240
Molecular Formula: C10H14O3
Formula Weight: 182.22
MOL File: 13184-86-6.mol

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Vanillyl ethyl ether Property

Boiling point:: 125°C/4mmHg(lit.)
Density: 1.087±0.06 g/cm3(Predicted)
refractive index: 1.5280 to 1.5320
FEMA: 3815 | VANILLYL ETHYL ETHER
storage temp.: Inert atmosphere,Room Temperature
form: clear liquid
pka: 9.73±0.20(Predicted)
color: Colorless to Almost colorless
Odor: at 20.00 % in ethyl alcohol. alcoholic rum sweet chocolate creamy vanilla spicy nutmeg smoky
Odor Type: chocolate
JECFA Number: 887
LogP: 1.46
CAS DataBase Reference: 13184-86-6
NIST Chemistry Reference: Phenol, 4-(ethoxymethyl)-2-methoxy-(13184-86-6)
EPA Substance Registry System: Phenol, 4-(ethoxymethyl)-2-methoxy- (13184-86-6)

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Safety

HS Code: 2909500090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: E1028
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Purity: >98.0%(GC)
Packaging: 5g
Price: $98
Updated: 2025/07/31

AK Scientific

Product number: J96485
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Packaging: 5g
Price: $30
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: FFG0000629
Product name: VANILLYL ETHYL ETHER
Purity: 98.00%
Packaging: 5MG
Price: $503.05
Updated: 2021/12/16

Ambeed

Product number: A198590
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Purity: 97%
Packaging: 1g
Price: $11
Updated: 2021/12/16

Ambeed

Product number: A198590
Product name: 4-(Ethoxymethyl)-2-methoxyphenol
Purity: 97%
Packaging: 5g
Price: $30
Updated: 2021/12/16

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Vanillyl ethyl ether Chemical Properties,Usage,Production

Chemical Properties

Vanillyl ethyl ether has a phenolic, smoky odor and a strong, pungent taste.

Occurrence

Reportedly present in grape brandy (cognac), rum, whiskey and vanilla.

Uses

flavors and fragrances

Definition

ChEBI: 4-(Ethoxymethyl)-2-methoxyphenol is a member of phenols and a member of methoxybenzenes.

Preparation

In a patented process, prepared by the reaction of cyclodextrin or branched-cyclodextrin with vanillyl alcohol.

Synthesis

121-33-5

122-51-0

13184-86-6

General procedure for the synthesis of vanillyl ethyl ether from vanillin and triethyl orthoformate: 3.04 g (20.0 mmol) of vanillin, 5.93 g (40.0 mmol) of triethyl orthoformate, 15.0 mg of p-toluenesulphonic acid monohydrate, and 15.0 mg 5% palladium-carbon catalyst were added to a 100 ml autoclave (equipped with an inner tube). After displacing the internal gas of the system under nitrogen protection, it was replaced with hydrogen and filled with hydrogen at 3.0 MPa. The autoclave temperature was controlled at 130°C and the reaction was continuously stirred for 1 hour. Upon completion of the reaction, the reaction mixture was cooled and the hydrogen pressure was subsequently released. The palladium carbon catalyst was removed by filtration and the unreacted triethyl orthoformate was recovered by distillation under reduced pressure, resulting in 3.60 g of vanillyl ethyl ether (97.4% purity and 96.2% yield as determined by internal standard method). The structure of the product was confirmed by 1H-NMR (CDCl3): δ=1.37 (3H, t), 3.42 (1H, q), 3.86 (3H, s), 4.44 (2H, s), 5.92 (1H, s), 6.88 (3H, m).

References

[1] Patent: EP2813482, 2014, A1. Location in patent: Paragraph 0139; 0140

Vanillyl ethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Vanillyl ethyl ether manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: Vanillyl ethyl ether 13184-86-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1
Release date: 2025-09-05

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Vanillyl ethyl ether 13184-86-6
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-20

JINING XINHE CHEMICAL CO., LTD

Product: Vanillyl ethyl ether 13184-86-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10ton
Release date: 2024-07-19

13184-86-6, Vanillyl ethyl etherRelated Search:

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4-[ETHOXYMETHYL]-2-METHOXYPHENOL

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Vanilla alcohol ether

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DAIRY ENHANCER

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13184-86-6 Vanillyl ethyl ether

Xianglan alcohol ether

13184-86-6

13181-86-6

3184-86-6