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Vanillyl ethyl ether

Product Name
Vanillyl ethyl ether
CAS No.
13184-86-6
Chemical Name
Vanillyl ethyl ether
Synonyms
FEMA 3815;DAIRY ENHANCER;VanilinEthylEther;ETHYL VANILLYL ETHER;VANILLYL ETHYL ETHER;Vanilla alcohol ether;Xianglan alcohol ether;13184-86-6 Vanillyl ethyl ether;4-[ETHOXYMETHYL]-2-METHOXYPHENOL;Phenol, 4-(ethoxymethyl)-2-methoxy-
CBNumber
CB2183240
Molecular Formula
C10H14O3
Formula Weight
182.22
MOL File
13184-86-6.mol
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Vanillyl ethyl ether Property

Boiling point:
125°C/4mmHg(lit.)
Density 
1.087±0.06 g/cm3(Predicted)
refractive index 
1.5280 to 1.5320
FEMA 
3815 | VANILLYL ETHYL ETHER
storage temp. 
Inert atmosphere,Room Temperature
form 
clear liquid
pka
9.73±0.20(Predicted)
color 
Colorless to Almost colorless
Odor
at 20.00 % in ethyl alcohol. alcoholic rum sweet chocolate creamy vanilla spicy nutmeg smoky
Odor Type
chocolate
JECFA Number
887
LogP
1.46
CAS DataBase Reference
13184-86-6
NIST Chemistry Reference
Phenol, 4-(ethoxymethyl)-2-methoxy-(13184-86-6)
EPA Substance Registry System
Phenol, 4-(ethoxymethyl)-2-methoxy- (13184-86-6)
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Safety

HS Code 
2909500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1028
Product name
4-(Ethoxymethyl)-2-methoxyphenol
Purity
>98.0%(GC)
Packaging
5g
Price
$98
Updated
2025/07/31
AK Scientific
Product number
J96485
Product name
4-(Ethoxymethyl)-2-methoxyphenol
Packaging
5g
Price
$30
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
FFG0000629
Product name
VANILLYL ETHYL ETHER
Purity
98.00%
Packaging
5MG
Price
$503.05
Updated
2021/12/16
AccelPharmtech
Product number
C1174
Product name
4-(Ethoxymethyl)-2-methoxyphenol
Purity
97.00%
Packaging
5G
Price
$2180
Updated
2021/12/16
AccelPharmtech
Product number
C1174
Product name
4-(Ethoxymethyl)-2-methoxyphenol
Purity
97.00%
Packaging
25G
Price
$4010
Updated
2021/12/16
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Vanillyl ethyl ether Chemical Properties,Usage,Production

Chemical Properties

Vanillyl ethyl ether has a phenolic, smoky odor and a strong, pungent taste.

Occurrence

Reportedly present in grape brandy (cognac), rum, whiskey and vanilla.

Uses

flavors and fragrances

Definition

ChEBI: 4-(Ethoxymethyl)-2-methoxyphenol is a member of phenols and a member of methoxybenzenes.

Preparation

In a patented process, prepared by the reaction of cyclodextrin or branched-cyclodextrin with vanillyl alcohol.

Synthesis

121-33-5

122-51-0

13184-86-6

General procedure for the synthesis of vanillyl ethyl ether from vanillin and triethyl orthoformate: 3.04 g (20.0 mmol) of vanillin, 5.93 g (40.0 mmol) of triethyl orthoformate, 15.0 mg of p-toluenesulphonic acid monohydrate, and 15.0 mg 5% palladium-carbon catalyst were added to a 100 ml autoclave (equipped with an inner tube). After displacing the internal gas of the system under nitrogen protection, it was replaced with hydrogen and filled with hydrogen at 3.0 MPa. The autoclave temperature was controlled at 130°C and the reaction was continuously stirred for 1 hour. Upon completion of the reaction, the reaction mixture was cooled and the hydrogen pressure was subsequently released. The palladium carbon catalyst was removed by filtration and the unreacted triethyl orthoformate was recovered by distillation under reduced pressure, resulting in 3.60 g of vanillyl ethyl ether (97.4% purity and 96.2% yield as determined by internal standard method). The structure of the product was confirmed by 1H-NMR (CDCl3): δ=1.37 (3H, t), 3.42 (1H, q), 3.86 (3H, s), 4.44 (2H, s), 5.92 (1H, s), 6.88 (3H, m).

References

[1] Patent: EP2813482, 2014, A1. Location in patent: Paragraph 0139; 0140

Vanillyl ethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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Vanillyl ethyl ether Suppliers

TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from Vanillyl ethyl ether manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
Vanillyl ethyl ether 13184-86-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1
Release date
2025-09-05
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Vanillyl ethyl ether 13184-86-6
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-11-20
JINING XINHE CHEMICAL CO., LTD
Product
Vanillyl ethyl ether 13184-86-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10ton
Release date
2024-07-19

13184-86-6, Vanillyl ethyl etherRelated Search:


  • VanilinEthylEther
  • 4-HYDROXY-3-METHOXYBENZYL ETHYL ETHER
  • 4-[ETHOXYMETHYL]-2-METHOXYPHENOL
  • Phenol, 4-(ethoxymethyl)-2-methoxy-
  • Vanilla alcohol ether
  • VANILLYL ETHYL ETHER
  • FEMA 3815
  • ETHYL VANILLYL ETHER
  • DAIRY ENHANCER
  • ETHYL 4-HYDROXY-3-METHOXYBENZYL ETHER
  • 13184-86-6 Vanillyl ethyl ether
  • Xianglan alcohol ether
  • 13184-86-6
  • 13181-86-6
  • 3184-86-6