Ethyl bromodifluoroacetate

Product Name: Ethyl bromodifluoroacetate
CAS No.: 667-27-6
Chemical Name: Ethyl bromodifluoroacetate
Synonyms: 2-broMo-2,2-difluoroacetate;EBDA;2-Bromo-2,2-difluoroacetic acid ethyl ester;EBFA;bromodifL;Ethyl bromodifluoroa;Ethylbromdifluoracetat;Twoethyl broMidefluoride;ETHYL BROMODIFLUOROACETATE;difluorobromo ethyl acetate
CBNumber: CB2238865
Molecular Formula: C4H5BrF2O2
Formula Weight: 202.98
MOL File: 667-27-6.mol

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Ethyl bromodifluoroacetate Property

Boiling point:: 112 °C/700 mmHg (lit.)
Density: 1.583 g/mL at 25 °C (lit.)
refractive index: n20/D 1.387(lit.)
Flash point:: 70 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Soluble in most organic solvents.
form: Liquid
color: Clear colorless to slightly yellow
Specific Gravity: 1.583
BRN: 1906095
InChI: InChI=1S/C4H5BrF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
InChIKey: IRSJDVYTJUCXRV-UHFFFAOYSA-N
SMILES: C(OCC)(=O)C(Br)(F)F
CAS DataBase Reference: 667-27-6(CAS DataBase Reference)
NIST Chemistry Reference: Ethyl bromodifluoroacetate(667-27-6)

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Safety

Hazard Codes: C,F,Xi
Risk Statements: 10-34-36
Safety Statements: 26-36/37/39-45-16-27
RIDADR: UN 2924 3/PG 2
WGK Germany: 3
Hazard Note: Irritant/Flammable
TSCA: No
HazardClass: 3
PackingGroup: II
HS Code: 29159000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 295795
Product name: Ethyl bromodifluoroacetate
Purity: 98%
Packaging: 5g
Price: $72.2
Updated: 2024/03/01

TCI Chemical

Product number: B1463
Product name: Ethyl Bromodifluoroacetate
Purity: >98.0%(GC)
Packaging: 5g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: B1463
Product name: Ethyl Bromodifluoroacetate
Purity: >98.0%(GC)
Packaging: 25g
Price: $53
Updated: 2024/03/01

Alfa Aesar

Product number: B20461
Product name: Ethyl bromodifluoroacetate, 97%
Packaging: 5g
Price: $65.65
Updated: 2024/03/01

TCI Chemical

Product number: B1463
Product name: Ethyl Bromodifluoroacetate
Purity: >98.0%(GC)
Packaging: 250g
Price: $306
Updated: 2024/03/01

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Ethyl bromodifluoroacetate Chemical Properties,Usage,Production

Description

Ethyl bromodifluoroacetate, a clear to yellow liquid, is an ester of bromodifluoroacetic acid and ethyl alcohol. It is an ester that can be used to introduce the CF2 group when synthesizing chemical compounds. Ethyl bromdifluoroacetate is considered to be a good compound in the generation of compounds and for testing with other organic compounds like lactones, imines, and other amino acids.

Chemical Properties

clear colorless to slightly yellow liquid

Uses

Ethyl bromodifluoroacetate, is used for the treatment of the Reformat sky reagent with aldehydes and ketones affords 2,2-difluoro-3-hydroxy esters. It is also used in the analysis of reagent purity through IR, NMR.

Uses

Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis. A Cu-catalyzed regioselective bromodifluoroacetylation of alkenes, using ethyl bromodifluoroacetate (BrCF2CO2Et) as a difluoroacetylating reagent.

Uses

Ethyl bromodifluoroacetate is usually used in the preparation of substituted ethyl 2′-pyridyldifluoroacetates,4-alkoxymethyl- and 4-aryloxymethyl-3,3-difluoropiperidines,α,α-difluoro-β-lactams,mono- and difluoromethylated phenanthridine derivatives.

Preparation

Difluorobromoacetonitrile is taken as a raw material, and prepared through a one-pot method and subjected to alcoholysis and esterification in ethanol aqueous solution to obtain ethyl bromodifluoroacetate.Reaction equation is:
BrF2CCN→BrF2CCOOH→BrF2CCOOC2H5

Ethyl bromodifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl bromodifluoroacetate Suppliers

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View Lastest Price from Ethyl bromodifluoroacetate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Ethyl bromodifluoroacetate 667-27-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Hebei Chuanghai Biotechnology Co,.LTD

Product: Ethyl bromodifluoroacetate 667-27-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.%
Supply Ability: 10 ton
Release date: 2024-08-23

Career Henan Chemical Co

Product: Ethyl bromodifluoroacetate 667-27-6
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-21

667-27-6, Ethyl bromodifluoroacetateRelated Search:

Difluoroacetic acid Ethyl difluoroacetate BROMODIFLUOROACETIC ACID METHYL BROMODIFLUOROACETATE Cuprous iodide Sulfuryl chloride Hydrazine sulfate Sodium ascorbate METHYL DIFLUOROACETATE Sodium chlorodifluoroacetate Diethyl 2,2-difluoromalonate Chlorodifluoroacetic acid ethyl ester 2-(2-Aminoethoxy)ethanol Bromoacetic acid Ethyl fluoroacetate Ethyl bromofluoroacetate Ethyl bromodifluoroacetate Ethyl bromoacetate

ETHYL BROMODIFLUOROACETATE

BROMODIFLUOROACETIC ACID ETHYL ESTER

2-Bromo-2,2-difluoroacetic acid ethyl ester

Difluorobromoacetic acid ethyl ester

Ethyl 2,2-Difluoro-2-Bromoac

Ethyl bromodifluoroa

2-Bromo-2,2-difluoro-1-ethoxyethan-1-one, 2-Bromo-2,2-difluoro-1-ethoxy-1-oxoethane

Ethyl broModifluoroacetate, 98% 5GR

Ethylbromdifluoracetat

2-broMo-2,2-difluoroacetate

2-Bromo-2,2-difluoro-1-ethoxyethan-1-one, 2-Bromo-2,2-difluoro-1-ethoxy-1-oxoethane, Bromo(difluoro)acetic acid ethyl ester

Twoethyl broMidefluoride

Ethyl broMoacetatetwo fluorine

Acetic acid, bromodifluoro-, ethyl ester

2,2-difluoro-2-bromoacetate ethyl

Ethyl bromodifluoroacetate 98%

difluorobromo ethyl acetate

Ethylbromodifluoroacetate98%

Acetic acid, 2-bromo-2,2-difluoro-, ethyl ester

Ethyl 2,2-difluoro-2-bromoacetate

Ethyl Bromodifluoroacetate &gt

Ethyl Bromodifluoroacetate,99%

bromodifL

TIANFU CHEM---Ethyl bromodifluoroacetate

EBDA

Ethyl bromoacetate difluoro

EBFA

667-27-6

C4H5BrF2O2

BrCF2COOCH2CH3

BrCF2CO2CH2CH3

Esters

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