6-FLUORONICOTINIC ACID METHYL ESTER

Product Name: 6-FLUORONICOTINIC ACID METHYL ESTER
CAS No.: 1427-06-1
Chemical Name: 6-FLUORONICOTINIC ACID METHYL ESTER
Synonyms: uoropyridine-3-carboxyL;METHYL6-FLUORONICOTINATE;Methyl6-Fluoronicotinate>6-fluoro-3-Pyridinecarboxyli;Methyl 6-fluoronicotinate 98%;6-FLUORONICOTINIC ACID METHYL ESTER;6-Fluoro-3-(Methoxycarbonyl)pyridine;Methyl 6-fluoropyridin-3-carboxylate;methyl 6-fluoro-3-pyridinecarboxylate;Methyl 6-fluoropyridine-3-carboxylate
CBNumber: CB2241511
Molecular Formula: C7H6FNO2
Formula Weight: 155.13
MOL File: 1427-06-1.mol

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6-FLUORONICOTINIC ACID METHYL ESTER Property

Melting point:: 48-52 °C
Boiling point:: 210.3±20.0 °C(Predicted)
Density: 1.243±0.06 g/cm3(Predicted)
Flash point:: 99 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: -2.47±0.10(Predicted)
form: Solid
color: White to Light yellow
InChI: InChI=1S/C7H6FNO2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3
InChIKey: HLYBWNNPVXFCPZ-UHFFFAOYSA-N
SMILES: C1=NC(F)=CC=C1C(OC)=O
CAS DataBase Reference: 1427-06-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-36/37/39-45
WGK Germany: 3
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 697850
Product name: Methyl 6-fluoropyridine-3-carboxylate
Purity: 97%
Packaging: 250mg
Price: $87.7
Updated: 2023/01/07

TCI Chemical

Product number: M2724
Product name: Methyl 6-Fluoronicotinate
Purity: >98.0%(GC)
Packaging: 1g
Price: $82
Updated: 2025/07/31

TCI Chemical

Product number: M2724
Product name: Methyl 6-Fluoronicotinate
Purity: >98.0%(GC)
Packaging: 5g
Price: $271
Updated: 2025/07/31

TRC

Product number: F593698
Product name: 6-Fluoronicotinicacidmethylester
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Apolloscientific

Product number: PC49205
Product name: Methyl 6-Fluoronicotinate
Purity: 98%
Packaging: 25g
Price: $358
Updated: 2021/12/16

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6-FLUORONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

403-45-2

18107-18-1

1427-06-1

General procedure for the synthesis of methyl 6-fluoronicotinate: 6-fluoronicotinate (255 mg, 1.32 mmol) was dissolved in methanol (5 mL) at room temperature, followed by the addition of (trimethylmethylsilyl) diazomethane (4.0 mL, 2 M of ether solution, 8.0 mmol). The reaction mixture was stirred at room temperature for 30 min and then concentrated. The resulting methyl 6-fluoronicotinate (129 mg, 47% yield) was used without further purification. Its nuclear magnetic resonance hydrogen spectrum (1H NMR, 600 MHz, DMSO-d6) data were as follows: δ 8.79 (d, J=2.6 Hz, 1H), 8.47 (td, J=7.9,2.6 Hz, 1H), 7.35 (ddd, J=8.5,2.6,0.6 Hz, 1H), 3.88 (s, 3H). The calculated value for electrospray ionization mass spectrometry (ESIMS) was 156.0 (M++H) and the measured value was 156.1 (M++H).

References

[1] Patent: WO2007/2248, 2007, A2. Location in patent: Page/Page column 76

6-FLUORONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-FLUORONICOTINIC ACID METHYL ESTER Suppliers

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View Lastest Price from 6-FLUORONICOTINIC ACID METHYL ESTER manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 6-FLUORONICOTINIC ACID METHYL ESTER 1427-06-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-30

Henan Fengda Chemical Co., Ltd

Product: 6-FLUORONICOTINIC ACID METHYL ESTER 1427-06-1
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Career Henan Chemical Co

Product: 6-FLUORONICOTINIC ACID METHYL ESTER 1427-06-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100KGS
Release date: 2018-12-14

1427-06-1, 6-FLUORONICOTINIC ACID METHYL ESTERRelated Search:

Ethyl 6-bromopicolinate Methyl nicotinate 2-FLUORONICOTINIC ACID METHYL ESTER 2-Fluoropyridine-5-carboxaldehyde 6-Fluoronicotinic acid METHYL 2,6-DIFLUORONICOTINATE 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE 2-Fluoro-5-methylpyridine 6-FLUORONICOTINIC ACID METHYL ESTER

6-FLUORONICOTINIC ACID METHYL ESTER

METHYL6-FLUORONICOTINATE

Methyl 6-fluoronicotinate 98%

methyl 6-fluoro-3-pyridinecarboxylate

Methyl 6-fluoropyridine-3-carboxylate

3-Pyridinecarboxylic acid, 6-fluoro-, methyl ester

Methyl 6-fluoropyridine-3-carboxylate, 6-Fluoro-3-(methoxycarbonyl)pyridine

6-fluoro-3-Pyridinecarboxylic acid Methyl ester

6-Fluoro-3-(Methoxycarbonyl)pyridine

6-fluoro-3-Pyridinecarboxyli

Methyl6-Fluoronicotinate&gt

uoropyridine-3-carboxyL

6-Fluoropyridine-3-carboxylic Acid Methyl Ester

6-FLUORONICOTINIC ACID METHYL ESTER ISO 9001：2015 REACH

3-Pyridinecarboxylic acid, 6-fluoro-, methyl ester (9CI, ACI)

6-fluoro-3-Pyridinecarboxylic acid methyl ester (9CI ACI)

6-Fluoropyridin-3-carboxylic acid methyl ester

Methyl 6-fluoropyridin-3-carboxylate

1427-06-1

C6H3FNO2

Imidazoles ,Homopiperidines

Fluorine series

Picolinic acid series

Pyridines

Boronic Acid

Pyridine

pharmacetical