RS 23597-190 HYDROCHLORIDE

Product Name: RS 23597-190 HYDROCHLORIDE
CAS No.: 149719-06-2
Chemical Name: RS 23597-190 HYDROCHLORIDE
Synonyms: RS23597-190HCl;RS 23597-190 hydroch;RS 23597-190 >=98% (HPLC);RS 23597-190 HYDROCHLORIDE;RS 23597 190 hydrochloride,RS 23597190 hydrochloride;3-(PIPERIDIN-1-YL)PROPYL-4-AMINO-5-CHLORO-2-METHOXYBENZOATE HCL;3-(PIPERIDIN-1-YL)PROPYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE HYDROCHLORIDE;3-piperidin-1-ylpropyl 4-azanyl-5-chloro-2-methoxy-benzoate hydrochloride;3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride;4-amino-5-chloro-2-methoxy-benzoic acid 3-piperidinopropyl ester hydrochloride
CBNumber: CB2242093
Molecular Formula: C16H24Cl2N2O3
Formula Weight: 363.28
MOL File: 149719-06-2.mol

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RS 23597-190 HYDROCHLORIDE Property

storage temp.: Sealed in dry,2-8°C
solubility: Water:36.33(Max Conc. mg/mL);100.0(Max Conc. mM)
form: Powder
Water Solubility: Soluble to 100 mM in water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1909
Product name: RS 23597-190
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $102
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1909
Product name: RS 23597-190
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $376
Updated: 2022/05/15

Tocris

Product number: 0728
Product name: RS23597-190hydrochloride
Packaging: 50
Price: $411
Updated: 2021/12/16

Tocris

Product number: 0728
Product name: RS23597-190hydrochloride
Packaging: 10
Price: $98
Updated: 2021/12/16

TRC

Product number: R700958
Product name: RS23597-190Hydrochloride
Packaging: 5mg
Price: $420
Updated: 2021/12/16

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RS 23597-190 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

RS 23597-190 Hydrochloride is a selective and competitive SR-4 and 5-HT4 receptor antagonist.

Biological Activity

A high affinity, selective competitive antagonist at 5-HT 4 receptors.

Biochem/physiol Actions

RS 23597-190 is a high affinity 5-HT4-selective antagonist with in vitro and in vivo efficacy. RS 23597-190 is a 4-amino-5-chloro-2-methoxybenzoate that antagonizes 5-HT-mediated relaxation of carbachol-contracted rat oesphageal muscularis mucosae ex vivo (pA2 = 7.5) and prevents 5-HT-induced tachycardia (tachyarrhythmia) of anaesthetized micropigs in vivo (6 mg/kg RS 23597-190 and 3-10 μ/kg 5-HT via i.v.) by targeting 5-HT4 with high affinity (pKB = 7.8) and selectivity, while exhibiting no efficacy against 5-methoxytryptamine-mediated 5-HT3 activation in guinea-pig ileum and displaying much reduced or little affinity toward 5-HT3 (pKi = 5.7/mouse NG108-15 cells and pKB <5/guinea-pig ileum), dopamine receptors (pKi <4/D1 & <3/D2), muscarinic receptors (pKi <4.5 toward M1/2/3/4), 5-HT1A & 5-HT2 (pKi <5.2).

storage

Store at RT

RS 23597-190 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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RS 23597-190 HYDROCHLORIDE Suppliers

China 17 Germany 1 South Korea 1 Switzerland 2 United Kingdom 5 United States 7 USA 1 Global 34

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 18089
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Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25014
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EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
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Beijing Haite lesk Technology Co., Ltd

Tel: 15210893940; 15116916250
Fax: QQ: 237008221
Email: chemistryliu@163.com
Country: China
ProdList: 7327
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Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44843
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Shanghai Universal Biotech Co.,Ltd

Tel: 18768175414
Email: gaojun@univ-bio.com
Country: China
ProdList: 24998
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24018
Advantage: 58

149719-06-2, RS 23597-190 HYDROCHLORIDERelated Search:

METHYL 5-CHLORO-2-METHOXYBENZOATE Methyl 4-amino-2-methoxybenzoate 5-Chloro-2-methoxybenzoic acid Methyl 5-chloro-2-hydroxybenzoate 5-Amino-4-chloro-2-methylphenol 4-AMINO-5-CHLORO-2-ETHOXYBENZOIC ACID 2-Ethoxy-4-amino-5-chlorobenzoic acid METHYL 4-AMINOSALICYLATE 2-Chloro-5-methoxyaniline METHYL 4-AMINO-3-CHLOROBENZOATE 5-Chloro-2-hydroxybenzoic acid 4-AMINO-2-METHOXYBENZOIC ACID 4-AMINO-3-CHLORO-BENZOIC ACID ETHYL ESTER RS 23597-190 HYDROCHLORIDE 4-Amino-3-chlorobenzoic acid

3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride

3-piperidin-1-ylpropyl 4-azanyl-5-chloro-2-methoxy-benzoate hydrochloride

4-amino-5-chloro-2-methoxy-benzoic acid 3-piperidinopropyl ester hydrochloride

3-(PIPERIDIN-1-YL)PROPYL-4-AMINO-5-CHLORO-2-METHOXYBENZOATE HCL

3-(PIPERIDIN-1-YL)PROPYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE HYDROCHLORIDE

RS 23597-190 HYDROCHLORIDE

RS23597-190HCl

4-amino-5-chloro-2-methoxybenzoic acid 3-(1-piperidinyl)propyl ester hydrochloride

RS 23597-190 >=98% (HPLC)

RS 23597-190 hydroch

Benzoic acid, 4-amino-5-chloro-2-methoxy-, 3-(1-piperidinyl)propyl ester, hydrochloride (1:1)

4-amino-5-chloro-2-methoxy-Benzoic acid 3-(1-piperidinyl)propyl ester hydrochloride (1:1)

RS 23597 190 hydrochloride,RS 23597190 hydrochloride

149719-06-2

C16H24Cl2N2O3

C16H23ClN2O3HCl