ChemicalBook > CAS DataBase List > 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester

3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester

Product Name
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
CAS No.
629664-81-9
Chemical Name
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
Synonyms
XL335;CS-899;Fxr 450;Way 362450;Unii-S6kdm312I5;WAY-362450 (XL335;Turofexorate isopropyl;WAY-362450 >=98% (HPLC);WAY362450 - FXR450 - XL335;XL335;TUROFEXORATE ISOPROPYL
CBNumber
CB22484921
Molecular Formula
C25H24F2N2O3
Formula Weight
438.47
MOL File
629664-81-9.mol
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3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Property

Boiling point:
617.3±55.0 °C(Predicted)
Density 
1.275
storage temp. 
room temp
solubility 
DMSO : 25 mg/mL (57.02 mM; Need ultrasonic)
pka
16.49±0.60(Predicted)
form 
powder
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0267
Product name
WAY-362450
Purity
≥98% (HPLC)
Packaging
5MG
Price
$112
Updated
2023/06/20
Sigma-Aldrich
Product number
PZ0267
Product name
WAY-362450
Purity
≥98% (HPLC)
Packaging
25MG
Price
$451
Updated
2023/06/20
Cayman Chemical
Product number
23350
Product name
XL335
Purity
≥98%
Packaging
5mg
Price
$97
Updated
2024/03/01
Cayman Chemical
Product number
23350
Product name
XL335
Purity
≥98%
Packaging
10mg
Price
$175
Updated
2024/03/01
Cayman Chemical
Product number
23350
Product name
XL335
Purity
≥98%
Packaging
25mg
Price
$385
Updated
2024/03/01
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3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Chemical Properties,Usage,Production

Definition

ChEBI: Turofexorate isopropyl is a member of indoles.

Biochem/physiol Actions

WAY-362450 is a potent and selective Farnesoid X receptor (FXR) agonist that lowers total plasma cholesterol (all lipoprotein species). WAY-362450 reduced the levels of high-density lipoprotein cholesterol (HDLc) in Cynomolgus monkeys, mice and hamsters. Apparently HDL lowering is achieved through increased transhepatic cholesterol efflux.

3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester Suppliers

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View Lastest Price from 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester manufacturers

Career Henan Chemical Co
Product
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester 629664-81-9
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-26

629664-81-9, 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl esterRelated Search:

WAY 181187 MAY-262611 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol XL-652 pilaralisib XL-765,SAR245409 XL019 XL-019 XL147 2-fluoro-6-(trifluoroMethyl)benzene-1-sulfonyl chloride GW 3965 HYDROCHLORIDE T0901317

  • 3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
  • Fxr 450
  • Turofexorate isopropyl
  • isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,4,5,5a,6,10b-octahydroazepino[4,5-b]indole-5-carboxylate
  • XL335;TUROFEXORATE ISOPROPYL
  • CS-899
  • XL335; WAY 362450; TUROFEXORATE ISOPROPYL; WAY-362450
  • Turofexorate isopropyl [usan]
  • Unii-S6kdm312I5
  • Way 362450
  • isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
  • isopropyl 3-(3,4-difluorobenzoyl)-1,1-diMethyl-1,2,3,6-tetrahydr
  • WAY362450 - FXR450 - XL335
  • XL335
  • Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxyla
  • (E)-isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
  • Turofexorate Isopropyl (XL335)
  • propan-2-yl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
  • WAY-362450 (XL335
  • Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carbox
  • Azepino[4,5-b]indole-5-carboxylic acid, 3-(3,4-difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethyl-, 1-methylethyl ester
  • WAY-362450 >=98% (HPLC)
  • Turofexorate isopropyl XL335 XL-335 WAY-362450 WAY362450
  • 629664-81-9
  • Inhibitors
  • A farnesoid X receptor (FXR) agonist .