Tylvalosin tartrate

Product Name: Tylvalosin tartrate
CAS No.: 63428-13-7
Chemical Name: Tylvalosin tartrate
Synonyms: Tylvalosin Tartrate;Acetylisovaleryltylosin Tartrate;Acetylisovaleryltylosin Tartrat;Tylosin, 3-acetate 4B-(3-methylbutanoate), (2R,3R)-2,3-dihydroxybutanedioate (salt);Aivlosin Tartrate;Tawanthin tartrate;TYLVALOSIN TARTRATE PREMIX;Acetylisovalerylosin tartrate;Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate;TIANFU-CHEM Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7
CBNumber: CB22534581
Molecular Formula: C57H93NO25
Formula Weight: 1192.35
MOL File: 63428-13-7.mol

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Tylvalosin tartrate Property

Melting point:: 208 - 211°C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
InChIKey: OLLSDNUHBJHKJS-YZBHKUDENA-N

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0099515
Product name: Tylvalosintartrate
Packaging: 25mg
Price: $50
Updated: 2021/12/16

Matrix Scientific

Product number: 097240
Product name: Acetylisovaleryltylosin tartrate
Purity: 80%
Packaging: 500mg
Price: $95
Updated: 2021/12/16

AK Scientific

Product number: 9668AB
Product name: Acetylisovaleryltylosintartrate
Packaging: 1g
Price: $145
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019489
Product name: ACETYLISOVALERYLTYLOSIN TARTRATE
Purity: 95.00%
Packaging: 1G
Price: $284.55
Updated: 2021/12/16

AK Scientific

Product number: J50036
Product name: Acetylisovaleryltylosintartrate,tech.
Packaging: 5g
Price: $298
Updated: 2021/12/16

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Tylvalosin tartrate Chemical Properties,Usage,Production

Uses

Tylvalosin Tartrate is an impurity of Tylvalosin (T898210); Tylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria.

Pharmacokinetics

Tylvalosin tartrate is a macrolide antibiotic with antibacterial activity against Gram-positive and some Gram-negative organisms and mycoplasma. It acts by inhibiting protein synthesis in the bacterial cell. Macrolide antibiotics are metabolites or semi-synthetic derivatives of metabolites of soil organisms obtained by fermentation. They have differently-sized lactone rings and are essential due to the dimethylamino group. Tylvalosin has a sixteen-membered ring. Macrolides interfere with protein synthesis by reversibly binding to the 50S ribosome subunit.

Pharmacology

Tylvalosin tartrate is rapidly absorbed after oral administration of Aivlosin. After administration of the recommended dose, lung concentrations of 0.060–0.066 μg/ml were found at 2 and 12 hours post-treatment. The parent compound is widely distributed in the tissues, with the highest concentrations found in the lungs, bile, intestinal mucosa, spleen, kidney, and liver. There is evidence that the concentration of macrolides is higher at the site of infection than in plasma, particularly in neutrophils, alveolar macrophages, and alveolar epithelial cells. In vitro metabolism studies have confirmed that the parent compound is rapidly metabolised to 3-O-acetyltylosin. In a trial with 14C-labeled Aivlosin administered at 2.125 mg/kg to pigs for 7 days, over 70% of the dose was excreted in the feces, with urinary excretion accounting for 3 to 4% of the dose.

in vitro

Tylvalosin tartrate (10 μg/mL; 0.5, 1 h) increases caspase-3 cleavage in porcine neutrophils, leading to DNA fragmentation during apoptosis.Tylvalosin tartrate (0.1-10 μg/mL; 0.5 h) Promote endocytosis of porcine neutrophils by macrophages without changing phagocytosis.

Tylvalosin tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tylvalosin tartrate Suppliers

Canada 1 China 179 India 5 United States 7 Global 192

Wuhan Hongde Yuexin Pharmatech Co.,Ltd

Tel: 027-83850116 18164090116
Fax: 027-83850116
Email: whhdyxchem123@sina.com
Country: China
ProdList: 4265
Advantage: 58

Jinan Wald Chemical Co., Ltd.

Tel: 0531-88773586 13210588999
Fax: 053188773586
Email: 304264064@qq.com
Country: China
ProdList: 193
Advantage: 58

Minglong (Xianning) Pharmaceutical Co., LTD

Tel: 155-7155-6913 15571556913
Email: 354024111@qq.com
Country: China
ProdList: 2614
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8837
Advantage: 52

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4554
Advantage: 62

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2866
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ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
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Email: shyysw007@163.com
Country: China
ProdList: 4940
Advantage: 60

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

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View Lastest Price from Tylvalosin tartrate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Tylvalosin Tartrate Premix 63428-13-7
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-22

ARCTIC EXPORTS INC

Product: Acetylisovaleryltylosin Tartrate 63428-13-7
Price: US $1.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 1000
Release date: 2023-12-28

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: 10tons
Release date: 2024-04-24

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Tylosin, 3-acetate 4B-(3-methylbutanoate), (2R,3R)-2,3-dihydroxybutanedioate (salt)

Acetylisovaleryltylosin Tartrat

Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate

Acetylisovaleryltylosin Tartrate

Aivlosin Tartrate

Tylvalosin Tartrate

(2S,3S,4R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-acetoxy-16-ethyl-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl)oxy)-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (2R,3R)-2,3-dihydroxysuccinic acid

(2R,3R,4R,5R,6R)-6-(((2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-5-Acetoxy-4-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl)methoxy)-4,5-dimethoxy-2-methyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (2R,3R)-2,3-dihydroxysuccinate

(2R,3R,4R,5R,6R)-6-(((2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-5-Acetoxy-4-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-14-hydroxy-5,9,13-trimeth

Tylvalosin TartrateQ: What is Tylvalosin Tartrate Q: What is the CAS Number of Tylvalosin Tartrate Q: What is the storage condition of Tylvalosin Tartrate

Tawanthin tartrate

TIANFU-CHEM Tylosin 3-acetate 4B-(3-methylbutanoate) (2R,3R)-2,3-dihydroxybutanedioate 63428-13-7

TYLVALOSIN TARTRATE PREMIX

Acetylisovalerylosin tartrate

63428-13-7

C53H87NO19xC4H6O6

C57H93NO25

C53H87NO19C4H6O6

API