Kinsenoside

Product Name: Kinsenoside
CAS No.: 151870-74-5
Chemical Name: Kinsenoside
Synonyms: Kinsenoside;(+)-Kinsenoside;(4R)-4-(beta-D-Glucopyranosyloxy)dihydro-2(3H)-furanone;2(3H)-Furanone, 4-(β-D-glucopyranosyloxy)dihydro-, (4R)-;(4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one;(R)-4-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)dihydrofuran-2(3H)-one;Keap1-Nrf2,Inhibitor,pulposus,disc,degeneration,Kinsenoside,inhibit,cells,nucleus,Nrf2,Apoptosis,intervertebral
CBNumber: CB22645474
Molecular Formula: C10H16O8
Formula Weight: 264.23
MOL File: 151870-74-5.mol

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Kinsenoside Property

Boiling point:: 570.2±50.0 °C(Predicted)
Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: DMF:14.0(Max Conc. mg/mL);52.98(Max Conc. mM)
DMSO:33.0(Max Conc. mg/mL);124.89(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);37.85(Max Conc. mM)
form: A crystalline solid
pka: 12.81±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25144
Product name: Kinsenoside
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 25144
Product name: Kinsenoside
Purity: ≥95%
Packaging: 5mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 25144
Product name: Kinsenoside
Purity: ≥95%
Packaging: 10mg
Price: $341
Updated: 2024/03/01

TRC

Product number: K570200
Product name: Kinsenoside
Packaging: 10mg
Price: $420
Updated: 2021/12/16

Usbiological

Product number: 300531
Product name: Kinsenoside
Packaging: 25mg
Price: $907
Updated: 2021/12/16

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Kinsenoside Chemical Properties,Usage,Production

Description

Kinsenoside is a glycoside originally isolated from A. formosanus that has diverse biological activities, including antihyperlipidemic, immunosuppressive, and anti-inflammatory properties. It increases lipolysis mediated by adipose triglyceride lipase and increases hydrolysis of triglycerides in C3H10T1/2 adipocytes. It also increases phosphorylation of peroxisome proliferator-activated receptor α (PPARα) and CREB as well as protein levels of SIRT1, PGC-1α, and carnitine palmitoyltransferase I. Kinsenoside downregulates the expression and phosphorylation of VEGF receptor 2 (VEGFR2) and inhibits crosstalk between the JAK2/STAT3 and PI3K/AKT signaling pathways in dendritic cells in vitro. It decreases the production of IFN-γ, IL-17, and TNF-α and increases the production of IL-10 in splenocytes isolated from mice with collagen-induced arthritis (CIA). Kinsenoside (300 mg/kg per day) decreases the expression of IL-1β, TNF-α, and matrix metalloproteinase-9 (MMP-9) and increases the expression of IL-10 in inflamed joints in a mouse model of collagen-induced arthritis and prevents paw edema and reduces the severity of arthritis.

Uses

Kinsenoside is an anti-hyperlipidemic agent isolated from the plant Anoect chilus.

Definition

ChEBI: (3R)-5-Oxotetrahydro-3-furanyl beta-D-glucopyranoside is a glycoside.

Kinsenoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Kinsenoside Suppliers

China 99 United States 7 Global 106

Chengdu Push Bio-Technology Co., Ltd.

Tel: 18080489829
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Chengdu Biopurify Phytochemicals Ltd.

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Shanghai Aspire Biological Technology Co., Ltd.

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Shanghai Macklin Biochemical Co.,Ltd.

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Wuhan ChemFaces Biochemical Co., Ltd.

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EMMX Biotechnology LLC

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Shanghai YuanYe Biotechnology Co., Ltd.

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View Lastest Price from Kinsenoside manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Kinsenoside 151870-74-5
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-24

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Kinsenoside

(4R)-4-(beta-D-Glucopyranosyloxy)dihydro-2(3H)-furanone

2(3H)-Furanone, 4-(β-D-glucopyranosyloxy)dihydro-, (4R)-

(4R)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-one

(+)-Kinsenoside

Keap1-Nrf2,Inhibitor,pulposus,disc,degeneration,Kinsenoside,inhibit,cells,nucleus,Nrf2,Apoptosis,intervertebral

(R)-4-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)dihydrofuran-2(3H)-one

151870-74-5