D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT

Product Name: D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
CAS No.: 103404-90-6
Chemical Name: D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
Synonyms: d-α-hydroxyglutaric acid disodium salt;sodiuM 2-hydroxypentanedioate;(r)-2-hydroxypentanedioic acid;Disodium (R)-2-hydroxyglutarate;(2R)-2-Hydroxypentanedioic acid;D-A-HYDROXYGLUTARIC ACID DISODIUM;SodiuM (R)-2-hydroxypentanedioate;D-α-Hydroxyglutaric acid disodium;isodium,(2R)-2-hydroxypentanedioate;D-α-Hydroxyglutaricaciddisodiumsalt
CBNumber: CB2266017
Molecular Formula: C5H9NaO5
Formula Weight: 172.11
MOL File: 103404-90-6.mol

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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Property

Melting point:: >291°C (dec.)
storage temp.: -20°C
solubility: PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
color: White to light yellow
optical activity: [α]/D 8.5±1.5°, c = 1 in NaOH
Water Solubility: Soluble to 100 mM in water
BRN: 5318041
Stability:: Hygroscopic
InChIKey: DZHFTEDSQFPDPP-HWYNEVGZSA-L

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Safety

WGK Germany: 3
HS Code: 29181990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 16859
Product name: D-α-Hydroxyglutaric acid disodium salt
Purity: ≥98.0% (GC)
Packaging: 10mg
Price: $78.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 16859
Product name: D-α-Hydroxyglutaric acid disodium salt
Purity: ≥98.0% (GC)
Packaging: 50mg
Price: $316
Updated: 2024/03/01

Cayman Chemical

Product number: 11605
Product name: D-α-Hydroxyglutaric Acid (sodium salt)
Purity: ≥95%
Packaging: 10mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 11605
Product name: D-α-Hydroxyglutaric Acid (sodium salt)
Purity: ≥95%
Packaging: 25mg
Price: $109
Updated: 2024/03/01

Sigma-Aldrich

Product number: H8378
Product name: D-α-Hydroxyglutaric acid disodium salt
Purity: ≥95% (GC)
Packaging: 100mg
Price: $519
Updated: 2024/03/01

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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Chemical Properties,Usage,Production

Description

D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.

Chemical Properties

Pale Orange Solid

Uses

A potential inhibitor of glutamate carboxypeptidase.

Biochem/physiol Actions

Biomarker for inborn errors of metabolism and cancer

storage

Store at -20°C

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Suppliers

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View Lastest Price from D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT manufacturers

Career Henan Chemical Co

Product: D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT 103404-90-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 500kg/month
Release date: 2019-08-01

103404-90-6, D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALTRelated Search:

25-hydroxy vitamin D Polyglutamic acid GLUTARIC ACID SODIUM SALT SODIUM 4-HYDROXYBUTYRATE D-LACTIC ACID SODIUM SALT D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT SQUALESTATIN DL-2-HYDROXYVALERIC ACID SODIUM SALT

D-alpha-Hydroxyglutaric acid disodiuM salt >=95% (GC)

Disodium (R)-2-hydroxyglutarate

D-α-Hydroxyglutaric Acid (sodium salt)

D-ALPHA-HYDROXYGLUTARIC ACID DISODIU

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT

D-ALPHA-HYDROXYGLUTARIC ACID DISODIUM SALT

D-A-HYDROXYGLUTARIC ACID DISODIUM

(r)-2-hydroxypentanedioic acid

d-α-hydroxyglutaric acid disodium salt

(2R)-2-Hydroxyglutaric Acid Disodium Salt

Pentanedioic acid,2-hydroxy-, disodium salt, (2R)-

sodiuM 2-hydroxypentanedioate

SodiuM (R)-2-hydroxypentanedioate

<SC>D</SC>-α-Hydroxyglutaric acid disodiuM salt

D-α-Hydroxypentanedioic acid disodium salt, 95%

D-.alpha.-Hydroxyglutaric Acid (sodium salt)

D-alpha-Hydroxyglutaric Acid Disodium

disodium:(2R)-2-hydroxypentanedioate

(2R)-2-Hydroxypentanedioic acid

isodium,(2R)-2-hydroxypentanedioate

D-α-Hydroxyglutaric acid disodium

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT USP/EP/BP

D-α-Hydroxyglutaricaciddisodiumsalt

D-3-Hydroxypentanedioic acid disodium salt

Pentanedioic acid, 2-hydroxy-, sodium salt (1:2), (2R)-

(2R)-2-hydroxy-Pentanedioic acid sodium salt (1:2)

D-α-Hydroxyglutaric Acid (sodium salt)

Pentanedioic acid,2-hydroxy-,disodium salt,(2R)-(9ci)

103404-90-6

C5H6Na2O5

Peptide Synthesis

Specialty Synthesis

Amino Acid Derivatives

Aliphatics

Chiral Reagents

Inhibitors