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C1Q, HUMAN

Product Name
C1Q, HUMAN
CAS No.
80295-33-6
Chemical Name
C1Q, HUMAN
Synonyms
C1Q, HUMAN;COMPLEMENT 1Q;COMPLEMENT 1Q, HUMAN;COMPLEMENT C1Q, HUMAN;COMPLEMENT C1Q PROTEIN;COMPLEMENT COMPONENT C1Q;COMPLEMENT C1Q PROTEIN HUMAN;COMPLEMENT COMPONENT C1Q FROM HUMAN*SERUM;activity:18-30units/mgproteinsalt-free,lyophilizedsolidbysds
CBNumber
CB2270821
Formula Weight
0
MOL File
Mol file
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C1Q, HUMAN Property

storage temp. 
-70°C
form 
solution ( 10 mM HEPES, pH 7.2. and 0.3 M NaCl )
biological source
human
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Safety

Hazard Codes 
B
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C1740
Product name
Complement component C1q from human serum
Purity
≥95% (SDS-PAGE)
Packaging
0.5mg
Price
$442
Updated
2024/03/01
Sigma-Aldrich
Product number
204876
Product name
Complement C1q, Human
Packaging
1mg
Price
$489
Updated
2024/03/01
Sigma-Aldrich
Product number
C1740
Product name
Complement component C1q from human serum
Purity
≥95% (SDS-PAGE)
Packaging
1mg
Price
$764
Updated
2024/03/01
Usbiological
Product number
365874
Product name
Complement 1q
Packaging
96Tests
Price
$824
Updated
2021/12/16
Usbiological
Product number
C0010-02H
Product name
Complement C1q, Human
Packaging
1mg
Price
$874
Updated
2021/12/16
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C1Q, HUMAN Chemical Properties,Usage,Production

Uses

Complement component C1q is an important regulator factor for platelet activation. This has been a topic for research, as platelet-leukocyte aggregates play an important role in inflammatory conditions such as coronary heart disease. In particular, C1q has been shown to inhibit collagen induced aggregation and enhance production of reactive oxygen species (ROS).

General Description

C1q, together with C1r and C1s, in the ratio of 1:2:2, form the C1 complex which is the first component of the classical complement pathway. C1q is composed of 18 polypeptide chains (six A, six B, six C) (MW 460 kDa). All contain an 81-aa collagen-like region composed of (Gly-Xaa-Yaa) repeating sequences close to the N-terminus. Three chains (A1B1C1) form a triple helix with the C-terminus forming the globular heads which may be structurally and functionally distinct domains.

Biochem/physiol Actions

≥150,000 C1qH50 units/mg and ≥70% C1q activity in normal human serum on a mg/mg basis

C1Q, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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C1Q, HUMAN Suppliers

China 18 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 7 Global 30
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82

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  • C1Q, HUMAN
  • COMPLEMENT COMPONENT C1Q
  • COMPLEMENT C1Q, HUMAN
  • COMPLEMENT C1Q PROTEIN
  • COMPLEMENT C1Q PROTEIN HUMAN
  • COMPLEMENT 1Q, HUMAN
  • COMPLEMENT COMPONENT C1Q FROM HUMAN*SERUM
  • activity:18-30units/mgproteinsalt-free,lyophilizedsolidbysds
  • COMPLEMENT 1Q
  • 80295-33-6
  • Complement
  • Plasma, Blood, and Related Proteins and Reagents
  • Plasma & Blood Proteins
  • Proteins and Derivatives
  • Biochemicals and Reagents
  • BioChemical