Reaction
ChemicalBook > CAS DataBase List > Tris(dibenzylideneacetone)dipalladium-chloroform adduct

Tris(dibenzylideneacetone)dipalladium-chloroform adduct

Reaction
Product Name
Tris(dibenzylideneacetone)dipalladium-chloroform adduct
CAS No.
52522-40-4
Chemical Name
Tris(dibenzylideneacetone)dipalladium-chloroform adduct
Synonyms
Pd2dba3.CHCl3;TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM CHLOROFORM COMPLEX;TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM(0) CHLOROFORM ADDUCT;Pd2(bda)3 CHCl3;TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM-CHLOROFORM;Tris(dibenzylideneacetone)dipalladium(0)-chloroform;chloroform,(1E,4E)-1,5-diphenylpenta-1,4-dien-3-one,palladium;Tris DBA;adium-chL;oroform adduct
CBNumber
CB2298434
Molecular Formula
C52H31Cl3O3Pd2
Formula Weight
1023.01
MOL File
52522-40-4.mol
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Tris(dibenzylideneacetone)dipalladium-chloroform adduct Property

Melting point:
131-135 °C(lit.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder
color 
Purple to black
Water Solubility 
Soluble in organic solvents. Insoluble in water.
Sensitive 
Air & Moisture Sensitive
InChIKey
NLYJPAJWGANOKG-CXKPDERJSA-N
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-38-40-48/20/22-36/37/38
Safety Statements 
36/37-37/39-26
WGK Germany 
3
TSCA 
No
HS Code 
28439000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
366315
Product name
Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct
Packaging
250mg
Price
$49.1
Updated
2024/03/01
Sigma-Aldrich
Product number
366315
Product name
Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct
Packaging
1g
Price
$178
Updated
2024/03/01
Alfa Aesar
Product number
044969
Product name
Tris(dibenzylideneacetone)dipalladium(0), complex with chloroform, Pd 20.6%
Packaging
1g
Price
$109
Updated
2024/03/01
Alfa Aesar
Product number
044969
Product name
Tris(dibenzylideneacetone)dipalladium(0), complex with chloroform, Pd 20.6%
Packaging
5g
Price
$396.65
Updated
2024/03/01
Strem Chemicals
Product number
46-3010
Product name
Tris(dibenzylideneacetone)dipalladium(0) chloroform adduct
Packaging
500mg
Price
$67
Updated
2024/03/01
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Tris(dibenzylideneacetone)dipalladium-chloroform adduct Chemical Properties,Usage,Production

Reaction

  1. Used for Pd-catalyzed asymmetric arylation, vinylation, and Allenylation of tert-cyclobutanols via enantioselective C−C Bond cleavage.
  2. Used for synthesis of chiral chromans through the Pd-catalyzed asymmetric allylic alkylation (AAA).
  3. Catalyst for double N-arylation of primary amines to synthesize multisubstituted carbazoles from 2,2‘biphenylylene ditriflates.
  4. Paladium catalyst for regioand enantioselective allylic alkylation of ketones through allyl enol carbonates.
  5. Used for Pd-catalyzed enantioselective C-3 allylation of 3-substituted-1H-indoles using trialkylboranes.
  6. Used for enantioselective construction of spirocyclic oxindolic cyclopentanes by Pd-catalyzed trimethylenemethane-[3+2]-cycloaddition.
  7. Used for Pd-catalyzed insertion of α-diazoesters into vinyl halides to generate α,β-unsaturated γ-amino Esters.
  8. Pd catalyst for decarboxylative asymmetric allylic alkylation of enol carbonates.
  9. Palladium catalyst for asymmetric addition of oxindoles and allenes.
  10. Catalyst for diastereoand enantioselective formal [3+2]-cycloaddition between substituted vinylcyclopropanes and electron-deficient olefins.
  11. Used for Pd-catalyzed asymmetric decarboxylative cycloaddition of vinylethylene carbonates with Michael sacceptors.
  12. Catalyst for enantioselective [6+4] cycloaddition of vinyl oxetanes with azadienes to access ten-membered heterocycles.




Chemical Properties

purple to black crystalline powder

Uses

suzuki reaction

Uses

Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct is a catalyst that is used in the preparation of anticancer activity of amino vinylindoles via palladium catalyzed coupling of hydrazone, haloindoles and amines.

Application

Tris(dibenzylideneacetone)dipalladium-chloroform adduct (Pd2dba3·CHCl3) was used in the following studies:
To compose the catalytic system for the preparation of homoallylpalladium complexes.These complexes underwent in situ Stille type cross coupling with various vinyltin reagents to afford the cyclized products bearing allyl appendages.
As palladium source in the asymmetric transformations of 3,4-epoxy-1-butene.
As catalyst for the Heck cross-coupling reaction of iodobenzene with styrene.
As cyclization catalyst.
As catalyst for [2+2+2] cycloaddtion of didehydrotriphenylenes to the corresponding extended triphenylenes.
As catalyst for the carbonylation of b,b-imidoyl iodides to the corresponding imidate esters used, in turn, to prepare cyclic, quaternary amino acids.

General Description

Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct (Pd2dba3·CHCl3) is reported to serve as effective precatalysts, or precursors to the active Pd(0) catalyst.

Biological Activity

N -myristoyltransferase-1 (NMT-1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. Exhibits antiproliferative activity against melanoma cells in vitro and in vivo . Also used as a cyclization catalyst.

Tris(dibenzylideneacetone)dipalladium-chloroform adduct Preparation Products And Raw materials

Raw materials

Sodium acetate Acetonitrile Ethanol tert-Butyl methyl ether Acetone Toluene Chloroform Benzaldehyde Diethyl ether Ammonium chloride Palladium chloride Dichloromethane Methanol Sodium hydroxide

Preparation Products

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Tris(dibenzylideneacetone)dipalladium-chloroform adduct Suppliers

Australia 1 Belgium 2 China 232 France 1 Germany 5 India 15 Japan 1 Switzerland 2 United Kingdom 8 United States 31 Global 298
Acros Organics (Part of Thermo Fisher Scientific )
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Fax
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Email
fo@acros.com
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Belgium
ProdList
3824
Advantage
58
Acros Organics
Tel
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Email
info@acros.com
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Belgium
ProdList
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View Lastest Price from Tris(dibenzylideneacetone)dipalladium-chloroform adduct manufacturers

Shanghai Daken Advanced Materials Co.,Ltd
Product
Tris(dibenzylideneacetone)dipalladium-chloroform adduct 52522-40-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98.00%
Supply Ability
100KG /month
Release date
2021-11-05
Wuhan LPBchem Technology Co.,Ltd
Product
Tris(dibenzylideneacetone)dipalladium-chloroform adduct 52522-40-4
Price
US $10.00-10.00/g
Min. Order
1g
Purity
0.98
Supply Ability
50KG
Release date
2020-11-26
Longyan Tianhua Biological Technology Co., Ltd
Product
Tris(dibenzylideneacetone)dipalladium-chloroform adduct 52522-40-4
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KG
Release date
2020-11-10

52522-40-4, Tris(dibenzylideneacetone)dipalladium-chloroform adductRelated Search:

Benzyl chloride Tris(hydroxymethyl)aminomethane Tricine Dibenzylideneacetone Benzyltrimethylammonium chloride Benzalacetone BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE) Benzyltriethylammonium chloride Tris(dibenzylideneacetone)dipalladium Tris(dibenzylideneacetone)dipalladium TRIS(DIMETHYLAMINO)ANTIMONY TRIS(DIMETHYLAMINO)SILANE Tris(dibenzylideneacetone)dipalladium Tris(triphenylphosphine)rhodiu Tris(dimethylaminomethyl)phenol Tris(hydroxymethyl)nitromethane Benzylacetone Chloroform

  • TRIS(DIBENZYLIDENEACETONE)(CHLOROFORM)-DI-PALLADIUM(0)
  • TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM(0) CHLOROFORM ADDUCT
  • TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM-CHLOROFORM ADDUCT
  • TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM CHLOROFORM COMPLEX
  • DIPALLADIUM(0)TRIS(DIBENZYLIDENEACETONE)-CHLOROFORM ADDUCT
  • DI-PALLADIUM-TRIS(DIBENZYLIDENEACETONE)CHLOROFORM COMPLEX
  • Dipalladiumtris(dibenzylideneacetone) chloroform adduct
  • TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM(0) CHLOROFORM ADDUCT 98+%
  • TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM-CHLOROFORM
  • Tris(dibenylideneacetone)dipalladium-chloroform
  • adium-chL
  • oroform adduct
  • Tris (dibenzylidene acetone)di palladiuM(O)-chloroforM addict
  • chloroform,(1E,4E)-1,5-diphenylpenta-1,4-dien-3-one,palladium
  • Tris DBA chloroform adduct
  • DIPALLADIUM(0)TRIS(DIBENZYLI
  • tris(dibenzylideneacetone)(chloroform)-di-p
  • Tris(dibenzylideneacetone)dipalladium-chloroform a
  • Pd2(bda)3 CHCl3
  • Tris(dibenzylideneacetone)dipalladium(0)-chloroform
  • Tris(dibenzylideneacetone)dipalladium(0), complex with chloroform, Pd 20.6%
  • Tris(dibenzylideneacetone)dipalladium-chloroform adduct,97%
  • Tris-(dibenzylideneacetone)-dipalladium(O)-chloroform adduct
  • Tris(Dibenzylideneacetone)Dipalladium(0), Complex With Chloroform, Pd
  • Pd2dba3.CHCl3
  • Tris DBA
  • Tris(dibenzylideneacetone)dipalladium(0) chloroform adduct [Pd > 20.2%]
  • Tris(dibenzylideneacetone)dipalladiuM-chloroforM adduct, 97% 1GR
  • Tris(dibenzylideneacetone)dipalladiuM (0) chloroforM adduct, Pd2(dba)3·CHCl3
  • Tris(Dibenzylideneacetone)DipalladiuM- ChloroforM AdduCL
  • 2,2'',3',6,6'',7'-hexaphenyldispiro[1-palladatricyclo[3.1.0.0^{1,3}]hexane-1,2'-[1,2]dipalladatricyclo[4.1.0.0^{2,4}]heptane-1',1''-[1]palladatricyclo[3.1.0.0^{1,3}]hexane]-2,2'',3',5,5'',6'-hexaene-4,4'',5'-trione
  • Tris(dibenzylideneacetone)dipalladium chloroform adduct 98%
  • (1E,4E)-1,5-diphenyl-3-penta-1,4-dienone
  • Tris(dibenzylideneacetone)dipalladium-chloroform adduct ISO 9001：2015 REACH
  • Tris(dibenzylideneacetone)dipalladium-chloroform adduct 52522-40-4
  • TRIS (DIBENZYLIDENEACETONE) DIPALLADIUM CHLOROFORM ADDUCT For Synthesis
  • Palladium, tris[μ-[(1,2-η:4,5-η)-(1E,4E)-1,5-diphenyl-1,4-pentadien-3-one]]di-, compd. with trichloromethane (1:1) (9CI, ACI)
  • Trismu-(1,2-eta:4,5-eta)-(1E,4E)-1,5-diphenyl-1,4-pentadien-3-onedi-palladium compd. with trichloromethane (1:1)
  • 52522-40-4
  • 52552-40-4
  • C52H43Cl3O3Pd2
  • C51H42O3Pd2CHCl3
  • Pd2C17H14O3CHCl3
  • C6H5CHCHCOCHCHC6H53Pd2CHCl3
  • C52Cl3H43O3Pd2
  • C35H29Cl3O2Pd
  • C6H5CHCHCOCHCHC6H53Pd2稢HCl3
  • 3C17H14OCHCl32Pd
  • Catalysis and Inorganic Chemistry
  • New Products for Chemical Synthesis May/June 2007
  • Homogeneous Pd Catalysts
  • organometallic complexes
  • Metal Compounds