ChemicalBook > CAS DataBase List > Amino-PEG5-t-butyl ester

Amino-PEG5-t-butyl ester

Product Name
Amino-PEG5-t-butyl ester
CAS No.
1446282-18-3
Chemical Name
Amino-PEG5-t-butyl ester
Synonyms
H2N-PEG5-tBu;Amino-PEG5-Boc;Amino-PEG5-COOtBu;NH2-PEG5-C2-COOtBu;NH2-PEG5-CH2CH2COOtBu;H2N-PEG5-CH2CH2COOtBu;Amino-PEG5-t-Bu Ester;Amino-PEG5-t-butyl este;Amino-PEG5-t-butyl ester;tert-butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate
CBNumber
CB23048678
Molecular Formula
C17H35NO7
Formula Weight
365.46
MOL File
1446282-18-3.mol
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Amino-PEG5-t-butyl ester Property

Boiling point:
439.1±40.0 °C(Predicted)
Density 
1.049±0.06 g/cm3(Predicted)
refractive index 
n/D 1.4534
storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
8.74±0.10(Predicted)
form 
viscous liquid
color 
Light yellowish
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
A615295
Product name
Amino-PEG5-t-butylester
Packaging
25mg
Price
$180
Updated
2021/12/16
TRC
Product number
A615295
Product name
Amino-PEG5-t-butylester
Packaging
100mg
Price
$450
Updated
2021/12/16
BroadPharm
Product number
BP-21698
Product name
Amino-PEG5-t-butylester
Purity
98%
Packaging
500mg
Price
$290
Updated
2021/12/16
Activate Scientific
Product number
AS103925
Product name
H2N-PEG5-CH2CH2COOtBu
Purity
95+%
Packaging
1g
Price
$421
Updated
2021/12/16
AK Scientific
Product number
0456DY
Product name
Amino-PEG5-t-butylester
Packaging
1g
Price
$789
Updated
2021/12/16
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Amino-PEG5-t-butyl ester Chemical Properties,Usage,Production

Description

Amino-PEG5-t-butyl ester is a PEG molecule consisting of an amino group and a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

reaction suitability

reagent type: cross-linking reagent

IC 50

PEGs; Alkyl/ether

Amino-PEG5-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Amino-PEG5-t-butyl ester Suppliers

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View Lastest Price from Amino-PEG5-t-butyl ester manufacturers

LAURENT
Product
NH2-PEG5-CH2CH2COOtBu 1446282-18-3
Price
US $200.00/g
Min. Order
1g
Purity
98%
Supply Ability
500kg
Release date
2025-11-17
Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG5-COOtBu 1446282-18-3
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-22

1446282-18-3, Amino-PEG5-t-butyl esterRelated Search:

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  • Amino-PEG5-t-butyl ester
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  • H2N-PEG5-CH2CH2COOtBu
  • NH2-PEG5-CH2CH2COOtBu
  • Amino-PEG5-COOtBu
  • tert-butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate
  • Amino-PEG5-Boc
  • Amino-PEG5-t-Bu Ester
  • H2N-PEG5-CH2CH2COOtBu/4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester
  • Amino-PEG5-t-butyl este
  • NH2-PEG5-C2-COOtBu
  • tert-butyl 3-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • H2N-PEG5-tBu
  • 1446282-18-3
  • peg