4-Pyridinecarboxaldehyde
Flavor Type Chemical Properties Uses- Product Name
- 4-Pyridinecarboxaldehyde
- CAS No.
- 872-85-5
- Chemical Name
- 4-Pyridinecarboxaldehyde
- Synonyms
- ISONICOTINALDEHYDE;PYRIDINE-4-CARBALDEHYDE;PYRIDINE-4-CARBOXALDEHYDE;4-PYRIDINECARBALDEHYDE;PYRIDINE-4-ALDEHYDE;4-pyrdine aldehyde;Isonicotinic aldehyde;4-PyridineCarboxyaldehyde;Pyridin-4-al;4-Formylpyrdine
- CBNumber
- CB2315397
- Molecular Formula
- C6H5NO
- Formula Weight
- 107.11
- MOL File
- 872-85-5.mol
4-Pyridinecarboxaldehyde Property
- Melting point:
- -4--2°C
- Boiling point:
- 71-73 °C/10 mmHg (lit.)
- Density
- 1.137 g/mL at 20 °C (lit.)
- vapor pressure
- 0.02 hPa (20 °C)
- refractive index
- n20/D 1.544(lit.)
- Flash point:
- 130 °F
- storage temp.
- Store at +2°C to +8°C.
- solubility
- 20g/l
- pka
- 12.05(at 30℃)
- form
- liquid (clear)
- color
- clear brown-yellow
- PH
- 7-8 (H2O, 20℃)(saturated aqueous solution)
- Water Solubility
- 20 g/L (20 ºC)
- Sensitive
- Air Sensitive
- BRN
- 105342
- InChIKey
- BGUWFUQJCDRPTL-UHFFFAOYSA-N
- LogP
- 0.12 at 30℃ and pH7
- CAS DataBase Reference
- 872-85-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Pyridinecarboxaldehyde(872-85-5)
- EPA Substance Registry System
- 4-Pyridinecarboxaldehyde (872-85-5)
Safety
- Hazard Codes
- Xi,F
- Risk Statements
- 36/37/38-10
- Safety Statements
- 26-36-36/37/39-16
- RIDADR
- UN 1989
- WGK Germany
- 1
- RTECS
- NR9400000
- F
- 8-10-23
- Hazard Note
- Irritant/Keep Cold/Air Sensitive
- TSCA
- Yes
- HazardClass
- 3.2
- PackingGroup
- III
- HS Code
- 29333999
- Toxicity
- LD50 orally in Rabbit: 2355 mg/kg LD50 dermal Rat > 2000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P62402
- Product name
- 4-Pyridinecarboxaldehyde
- Purity
- 97%
- Packaging
- 25g
- Price
- $67.8
- Updated
- 2024/03/01
- Product number
- P62402
- Product name
- 4-Pyridinecarboxaldehyde
- Purity
- 97%
- Packaging
- 100g
- Price
- $245
- Updated
- 2024/03/01
- Product number
- I0143
- Product name
- 4-Pyridinecarboxaldehyde
- Purity
- >96.0%(GC)
- Packaging
- 25mL
- Price
- $43
- Updated
- 2024/03/01
- Product number
- I0143
- Product name
- 4-Pyridinecarboxaldehyde
- Purity
- >96.0%(GC)
- Packaging
- 500mL
- Price
- $581
- Updated
- 2021/12/16
- Product number
- A10656
- Product name
- Pyridine-4-carboxaldehyde, 97%
- Packaging
- 25g
- Price
- $44.4
- Updated
- 2024/03/01
4-Pyridinecarboxaldehyde Chemical Properties,Usage,Production
Flavor Type
Flavor Type: fruity
Chemical Properties
4-Pyridinecarboxaldehyde(4PCA) is a slightly yellow oily liquid. Its relative density is 1.122, and its refractive index is 1.5352 (25°C). Flash point is 54 ° C. 4-Pyridinecarboxaldehyde is soluble in water and ether.4-Pyridinecarboxaldehyde, also commonly called pyridine-2-carboxaldehyde, is an organic compound with the formula NC5H4CHO. 4-Pyridinecarboxaldehyde is a colorless oily liquid with a distinctive odor. Older samples are often brown-colored owing to impurities.
Uses
4-Pyridinecarboxaldehyde is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.4-Pyridinecarboxaldehyde and some of its derivatives have also been reported as useful transamination reagents to introduce ketone or aldehyde groups onto the N-termini of antibodies for subsequent site-specifically conjugate aminooxy-functionalized molecules (including fluorescent dyes, polyethylene glycol, or porphyrins) to these entities.
4-Pyridinecarboxaldehyde can be used for the synthesis of: β-Unsaturated amides by coupling with N,N-disubstituted formamides; meso-Substituted A3-corroles; N-(4-pyridylmethyl)-L-valine as a ligand to construct zinc metal–organic frameworks (Zn-MOFs); 4′-Pyridyl terpyridines, with potential application as anticancer and antimicrobial agents; 4-pyridinecarboxaldehyde thiosemicarbazone, as a corrosion inhibitor for mild steel.
Chemical Properties
clear yellow-brown liquid. soluble in water and ether.
Uses
4-Pyridinecarboxaldehyde, is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.
Uses
4-Pyridinecarboxaldehyde can be used for the synthesis of:
- ?,β-Unsaturated amides by coupling with N,N-disubstituted formamides.
- meso-Substituted A3-corroles.
- N-(4-pyridylmethyl)-L-valine as a ligand to construct zinc metal–organic frameworks (Zn-MOFs).
- 4′-Pyridyl terpyridines, with potential application as anticancer and antimicrobial agents.
- 4-pyridinecarboxaldehyde thiosemicarbazone, as a corrosion inhibitor for mild steel.
Preparation
4-Pyridinecarbaldehyde is synthesized by oxidation of 4-picoline. The mixed gas of 4-picoline and air is passed through the vanadium-molybdenum catalyst layer heated to 400°C, and oxidized to generate 4-pyridinecarbaldehyde.
Synthesis Reference(s)
Synthetic Communications, 20, p. 3385, 1990 DOI: 10.1080/00397919008051576
Purification Methods
Purified as for pyridine-2-aldehyde. [Beilstein 21 III/IV 2529, 21/7 V 351.]
4-Pyridinecarboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Pyridinecarboxaldehyde manufacturers
- Product
- 4-Pyridinecarboxaldehyde 872-85-5
- Price
- US $6.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 95%
- Supply Ability
- 1000kg
- Release date
- 2024-05-13
- Product
- 4-Pyridinecarboxaldehyde 872-85-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 4-Pyridinecarboxaldehyde 872-85-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99.%
- Supply Ability
- 10 ton
- Release date
- 2024-08-21