4-HYDROXY-3-METHOXYCINNAMALDEHYDE
- Product Name
- 4-HYDROXY-3-METHOXYCINNAMALDEHYDE
- CAS No.
- 458-36-6
- Chemical Name
- 4-HYDROXY-3-METHOXYCINNAMALDEHYDE
- Synonyms
- CONIFERYL ALDEHYDE;CONIFERALDEHYDE;2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-;AT-51107;p-Coniferaldehyde;coniferylaldehydel;Eugenol EP Impurity K;Ferulic Acid Impurity 3;3-(4-Hydroxy-3-methoxyphenyl);Coniferaldehyde, 10 mM in DMSO
- CBNumber
- CB2345336
- Molecular Formula
- C10H10O3
- Formula Weight
- 178.18
- MOL File
- 458-36-6.mol
4-HYDROXY-3-METHOXYCINNAMALDEHYDE Property
- Melting point:
- 80-82 °C(lit.)
- Boiling point:
- 175 °C5 mm Hg(lit.)
- Density
- 1.1562 g/cm3 (101.5 ºC)
- refractive index
- 1.65635
- Flash point:
- 175°
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 9.65±0.31(Predicted)
- form
- Solid
- color
- Brown
- Odor
- at 50.00 % in dipropylene glycol. sweet graham cracker cookie bread crust bread baked toasted grain barley roasted barley vanilla custard dairy
- Odor Type
- bready
- Stability:
- Air Sensitive
- InChI
- InChI=1S/C10H10O3/c1-13-10-7-8(3-2-6-11)4-5-9(10)12/h2-7,12H,1H3
- InChIKey
- DKZBBWMURDFHNE-UHFFFAOYSA-N
- SMILES
- C(=O)C=CC1=CC=C(O)C(OC)=C1
- LogP
- 1.160
- EPA Substance Registry System
- 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- (458-36-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 382051
- Product name
- 4-Hydroxy-3-methoxycinnamaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $101
- Updated
- 2025/07/31
- Product number
- 382051
- Product name
- 4-Hydroxy-3-methoxycinnamaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $362
- Updated
- 2025/07/31
- Product number
- FH74153
- Product name
- 4-Hydroxy-3-methoxycinnamaldehyde
- Packaging
- 5G
- Price
- $600
- Updated
- 2021/12/16
- Product number
- CHM0115024
- Product name
- 4-HYDROXY-3-METHOXYCINNAMALDEHYDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $653.23
- Updated
- 2021/12/16
- Product number
- CS-0022807
- Product name
- Coniferaldehyde
- Purity
- >98.0%
- Packaging
- 50mg
- Price
- $120
- Updated
- 2021/12/16
4-HYDROXY-3-METHOXYCINNAMALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from stinking fir; silver white maple Acer saccharinum, gray walnut Juglans cinerea, Quercus sp., North American red cedar Sequoia sp.
Uses
4-Hydroxy-3-methoxycinnamaldehyde is suitable for use in a study to investigate the antioxidant and antiradical activities of ferulates using a β-carotene-linoleate model system and a DPPH radical scavenging assay, respectively.
Definition
ChEBI: A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3.
General Description
4-Hydroxy-3-methoxycinnamaldehyde is an isoflavonoid. It has been isolated from the insecticidally active hot dichloromethane extract of heartwood of Gliricidia sepium, seed kernels of Melia azedarach L and barks of Cinnamomum cebuense.
in vivo
Coniferaldehyde (0.05 mmol kg/day; i.p; for 6 weeks) activates the Nrf2 signaling pathway in primary chondrocytes and articular cartilage from the knee joints. And Coniferaldehyde alleviates cartilage destruction in OA mice[2].
| Animal Model: | B6 male mice (26 g; 8-10 weeks old), surgical-induced osteoarthritis (OA)[2] |
| Dosage: | 0.05 mmol kg/day (approx. 8.9 mg/kg) |
| Administration: | i.p; for 6 weeks |
| Result: | Evidently alleviated the medial meniscus cartilage damage in mice subjected to the destabilization. |
4-HYDROXY-3-METHOXYCINNAMALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-HYDROXY-3-METHOXYCINNAMALDEHYDE manufacturers
- Product
- 4-HYDROXY-3-METHOXYCINNAMALDEHYDE 458-36-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12