D-(-)-Salicin

ChemicalBook > CAS DataBase List > D-(-)-Salicin

Description

Product Name: D-(-)-Salicin
CAS No.: 138-52-3
Chemical Name: D-(-)-Salicin
Synonyms: SALICIN;D-SALICIN;SALICOSIDE;WHITE WILLOW;Salicine;Salicylin;Salicin-RM;SALICIN(RG);SALICIN(SH);Salicin >
CBNumber: CB2349192
Molecular Formula: C13H18O7
Formula Weight: 286.28
MOL File: 138-52-3.mol

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D-(-)-Salicin Property

Melting point:: 196-202 °C
alpha: -61.5 º (c=5, water)
Boiling point:: 388.65°C (rough estimate)
Density: 1.4340
refractive index: -62 ° (C=3, H2O)
storage temp.: 2-8°C
solubility: 36g/l
form: Fine Crystalline Powder
pka: 12.80±0.70(Predicted)
color: White
Water Solubility: 36 g/L (15 ºC), 250 g/L (60 ºC)
Merck: 14,8324
BRN: 89593
Stability:: Stable, but light sensitive. Incompatible with strong oxidizing agents.
InChIKey: NGFMICBWJRZIBI-MICYEWLZSA-N
LogP: -1.232 (est)
CAS DataBase Reference: 138-52-3(CAS DataBase Reference)
NIST Chemistry Reference: Salicin(138-52-3)
EPA Substance Registry System: .beta.-D-Glucopyranoside, 2-(hydroxymethyl)phenyl (138-52-3)

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37-37-24/25-36
WGK Germany: 3
RTECS: LZ5901700
F: 3-10
TSCA: Yes
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S0625
Product name: D-(?)-Salicin
Purity: ≥99% (GC)
Packaging: 5g
Price: $57.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 79588
Product name: D-(?)-Salicin
Purity: analytical standard
Packaging: 100mg
Price: $230
Updated: 2024/03/01

TCI Chemical

Product number: S0003
Product name: Salicin
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $34
Updated: 2024/03/01

TCI Chemical

Product number: S0003
Product name: Salicin
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $98
Updated: 2024/03/01

Alfa Aesar

Product number: A16524
Product name: D-(-)-Salicin, 99%
Packaging: 5g
Price: $40.2
Updated: 2024/03/01

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D-(-)-Salicin Chemical Properties,Usage,Production

Description

D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.

Chemical Properties

white crystals or powder

Uses

analgesic, antipyretic

Uses

H1 antihistamine (nonsedating)

Uses

Standard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929).

Uses

D-(-)-Salicin has been used:

to study its in vitro anticoagulant and antiplatelet activities
as a standard in high performance liquid chromatography method (HPLC) for quantitation of salicin from willow plant
as a tastant in taste threshold assay
as a constituent of nutrient agar-salicin medium for selective isolation of Lactobacillus paracasei

Definition

ChEBI: An aryl beta-D-glucoside that is the beta-D-glucoside of the phenolic hydroxy group of salicyl alcohol.

General Description

Salicin is a non-phenolic glucosidic compound extracted from meadowsweet (Filipendula ulmaria L). It is majorly used as a substitute for quinine. Salicin can be used as a therapeutic for patients suffering from rheumatic fever. Salicin acts a metabolic precursor for salicylic acid. It is a novel phytochemical that exhibits immunological cross functions in plants and humans. Salicin facilitates growth and reproduction in plants. In addition, It also protects plants against biotic and abiotic stress.

Biochem/physiol Actions

D-(?)-Salicin exerts anti-rheumatism and anti-inflammatory activities. It inhibits lipopolysaccharide (LPS) induced inflammation in in vitro and in vivo studies. It regulates different signaling pathways such as nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK). It also regulates cytokines concentration such as tumor necrosis factor-alpha(TNF-α), interleukin-1β, interleukin-6, and interleukin-10.

Purification Methods

Crystallise D(-)-salicin from EtOAc, EtOH or water and sublime it at 190-195o/12mm. [Armour et al. J Chem Soc 412 1961, IR: Pearl & Darling J Org Chem 24 731 1959, Beilstein 17 III/IV 2986, 17/7 V 113.]

D-(-)-Salicin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from D-(-)-Salicin manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Salicin Powder 138-52-3
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-18

Changsha Staherb Natural Ingredients Co., Ltd.

Product: D-(-)-Salicin 138-52-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 15%-98% HPLC
Supply Ability: 1000KG
Release date: 2022-09-20

WUHAN FORTUNA CHEMICAL CO., LTD

Product: D-(-)-Salicin 138-52-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 10tons/month
Release date: 2024-07-09

138-52-3, D-(-)-SalicinRelated Search:

Icariin Ursolic acid Matrine Willow Bark Extract Salicylamide WhiteWillowBarkExtract Salicin benzoate,2-(hydroxymethyl)phenyl-beta-D-glucopyranoside 6-benzoate D-(-)-Salicin CURCULIGOSIDE SAPONARIN Salicylaldehyde TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN PHENYL-BETA-D-GLUCOPYRANOSIDE (2'-METHOXYCARBONYL)PHENYL-2-,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSE (2'-METHOXYCARBONYL) PHENYL-BETA-D-GLUCOPYRANOSIDE LEIOCARPOSIDE ALOENIN A MYCOPHENOLIC ACID GLUCURONIDE

D-(-)-SALICIN

D-SALICIN

2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOPYRANOSIDE

2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOPYYRANOSIDE

2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOSIDE

2-(Hydroxymethyl)phenyl hexopyranoside

SALICYLALDEHYDE-B-D-GLUCOSIDE

SALICYLALCOHOL BETA-D-GLUCOSIDE

SALICYL ALCOHOL GLUCOSIDE

SALICOSIDE

SALICIN

SALIGENIN-B-D-GLUCOSIDE

SALIGENIN-B-D-GLYCOPYRANOSIDE

WHITE WILLOW

D-()-Salicin 138-52-3

2-(Hydroxymethyl)phenyl-β-D-glucopyranoside

alpha-hydroxy-o-tolyl beta-D-glucopyranoside

White willow bark P.E Salicin 15% 25% 30% HPLC

SALICIN, 98+% HPLC

D-SALICIN, FOR BIOCHEMISTRY

SalicinForMicrobiology

2-(hydroxymethyl)phenyl-beta-d-glucopyranosid

Benzyl alcohol, o-hydroxy-, O-glucoside

beta-D-Glucopyranoside, 2-(hydroxymethyl)phenyl

beta-d-glucopyranoside,2-(hydroxymethyl)phenyl

o-(Hydroxymethyl)phenyl beta-D-glucopyranoside

Salicine

Saligenin-beta-D-glucopyranoside

saligeninbeta-d-glucopyranoside

β-D-Glucopyranoside, 2-(hydroxymethyl)phenyl

(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol

SALICIN(AHP)

SALICIN(RG)

Saligenin-β-D-glucopyranoside

D(-)-Salicin, 99+%

White Willow Bark P.E or Salicin

D-Salicin, natural

(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)-phenoxy)tetrahydro-2H-pyran-3,4,5-trio

Salicin from Plant Extract≥ 98% (HPLC)

Salicin/Salix alba extract

SALICIN(SH)

saligenin-β-glucopyranoside

saligenin glucoside

SALICIN ((2-HYDROXYMETHYL-PHENYL)-SS-D-GLUCOPYRANOSIDE)

D-(-)-SALICIN WITH HPLC

D-(-)-SALICIN hplc

Salix alba L.

2-(Hydroxymethyl)phenyl-β-D-glucopyranoside, D(-)-Salicin

1-b-D-Glucosyloxy-2-hydroxymethylbenzene

o-(Hydroxymethyl)phenyl b-D-glucopyranoside

D-()-Salicin ,98%

2-(Hydroxymethyl)phe

D(-)-Salicin, 99+% 25GR

(2R,3S,4S,5R,6S)-2-(HydroxyMethyl)-6-(2-(hydroxyMethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol

Salicin (Salicoside, Salicine)

Salicoside, Salicine

White Willow Extract (Standard)

Salicin &gt