ChemicalBook > CAS DataBase List > 3,3-Diphenyl-L-alanine

3,3-Diphenyl-L-alanine

Product Name: 3,3-Diphenyl-L-alanine
CAS No.: 149597-92-2
Chemical Name: 3,3-Diphenyl-L-alanine
Synonyms: H-DPH-OH;H-Dip-OH;H-L-Dip-OH;CAS:149597-92-2;L-DiPhenylalanine;H-(3-PHENYL)PHE-OH;RARECHEM BK PT 0193;(S)-DIPHENYLALANINE;3-Diphenyl-L-alanine;L-3,3-DIPHENYLALANINE
CBNumber: CB2352404
Molecular Formula: C15H15NO2
Formula Weight: 241.29
MOL File: 149597-92-2.mol

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3,3-Diphenyl-L-alanine Property

Melting point:: 234-240 °C
Boiling point:: 389.2±30.0 °C(Predicted)
Density: 1.198±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 2.11±0.10(Predicted)
color: White
InChI: InChI=1/C15H15NO2/c16-14(15(17)18)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H,16H2,(H,17,18)/t14-/s3
InChIKey: PECGVEGMRUZOML-AWEZNQCLSA-N
SMILES: C([C@H](N)C(=O)O)(C1=CC=CC=C1)C1=CC=CC=C1 |&1:1,r|
CAS DataBase Reference: 149597-92-2(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2922498590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 86998
Product name: 3,3-Diphenyl-L-alanine
Purity: ≥98.0% (HPLC)
Packaging: 1g
Price: $282
Updated: 2023/06/20

TRC

Product number: D462640
Product name: L-3,3-Diphenylalanine
Packaging: 500mg
Price: $70
Updated: 2021/12/16

Usbiological

Product number: 453139
Product name: L-3,3-Diphenylalanine
Packaging: 100mg
Price: $305
Updated: 2021/12/16

Chem-Impex

Product number: 04129
Product name: 3,3-Diphenyl-L-alanine,99%(ChiralHPLC)
Purity: 99%(ChiralHPLC)
Packaging: 5G
Price: $297.92
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD48021
Product name: 3,3-Diphenyl-L-alanine
Packaging: 2g
Price: $193.4
Updated: 2021/12/16

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3,3-Diphenyl-L-alanine Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

3,3-Diphenyl-L-alanine is used as organic chemical synthesis intermediate.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

1004755-24-1

149597-92-2

Step 2: 1,1-dimethylethyl-(2R)-(2,6-dichlorophenyl)-(4S)-(diphenylmethyl)-5-oxo-3-((1'R)-phenylethyl)tetrahydro-1H-1-imidazolecarboxylate (188 mg, 0.31 mmol) was dissolved in a solvent mixture of 7.5 mL of tetrahydrofuran and 1 mL of 1 M hydrochloric acid, and the atmosphere of the reaction vessel was replaced with nitrogen. . To the mixture was added 90 mg of 20% palladium-carbon hydroxide catalyst; the atmosphere was again replaced with nitrogen and then hydrogen. After 100 hours of reaction at room temperature and 2.2 MPa hydrogen pressure, the catalyst was separated by filtration. The resulting product was washed once with 5 mL of tetrahydrofuran and 3 mL of distilled water, respectively, and the solvent was removed under reduced pressure. To the mixture was added 7.5 mL of 6M hydrochloric acid; the mixture was heated and refluxed at an external temperature of 120-130°C for 2.5 hours. Thereafter, the reaction mixture was cooled to an external temperature of 0°C. After adjusting the pH to 6 to 7 by adding 30% aqueous sodium hydroxide solution thereto, the solvent was removed under reduced pressure. The amount of (S)-2-amino-3,3-diphenylpropionic acid contained in the residue was determined under the following analytical conditions. As a result, the yield was 76% and the ee value was 95.7%.

References

[1] Patent: EP2050738, 2009, A1. Location in patent: Page/Page column 39-40

3,3-Diphenyl-L-alanine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3-Diphenyl-L-alanine Suppliers

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View Lastest Price from 3,3-Diphenyl-L-alanine manufacturers

Honest Joy Holdings Limited

Product: L-3,3-Diphenylalanine 149597-92-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100 tons
Release date: 2022-02-08

Career Henan Chemical Co

Product: 3,3-Diphenyl-L-alanine 149597-92-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

149597-92-2, 3,3-Diphenyl-L-alanineRelated Search:

DL-beta-Homophenylalanine D-Alanine 6-Aminocaproic acid Biphenyl Glycine Chlorodiphenylphosphine L-Alanine EC 2.6.1.2 Phenprobamate ALTRENOGEST L-CYSTEIC ACID L-3,4-DIFLUOROPHENYLALANINE L-3,5-DIFLUOROPHE Tris(hydroxymethyl)aminomethane Fmoc-3,3-diphenyl-L-alanine Phenylacetic acid Boc-3,3-Diphenyl-L-alanine 3,3-DIPHENYL-D-ALANINE

L-Ala(3,3-diphenyl)-OH

3,3-DIPHENYL-L-ALANINE

(S)-DIPHENYLALANINE

(S)-2-AMINO-3,3-DIPHENYL-PROPIONIC ACID

RARECHEM BK PT 0193

BETA-PHENYL-L-PHENYLALANINE

H-DPH-OH

H-ALA(3,3-DIPHENYL)-OH

H-(3-PHENYL)PHE-OH

L-3,3-DIPHENYLALANINE

L-DiPhenylalanine

beta-Phenyl-L-phenylalanin

H-L-Dip-OH

L-3,3-Diphenyl-Ala-OH

(S)-2-amino-3,3-diphenylpropanoic acid

β-Phenyl-L-phenylalanine

3-Diphenyl-L-alanine

(2S)-2-Amino-3,3-diphenylpropanoic acid

L-DiPhenylalanine L-DiPhenylalanine

β-Phenyl-L-phenylalanine, (S)-2-Amino-3,3-diphenylpropionic acid

L-Phenylalanine, b-phenyl-

L-Phenylalanine, β-phenyl-

3,3-Diphenyl-L-alanine USP/EP/BP

β-Phenyl-L-Phenylalanin

CAS:149597-92-2

3,3-Diphenyl-<sc>L</sc>-alanine

H-Dip-OH

149597-92-2

Alanine Derivatives

Peptide Synthesis

Unnatural Amino Acid Derivatives

Specialty Synthesis

a-amino

Phenylalanine analogs and other aromatic alpha amino acids

Amino Acids

Amino Acid Derivatives

Peptide

unnatural amino acids