U-73343

Product Name: U-73343
CAS No.: 142878-12-4
Chemical Name: U-73343
Synonyms: U-73343;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;U-73343,Inhibitor,U73343,Phospholipase,inhibit;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-;U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
CBNumber: CB2377935
Molecular Formula: C29H42N2O3
Formula Weight: 466.66
MOL File: 142878-12-4.mol

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U-73343 Property

Boiling point:: 641.5±55.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: +15C to +30C
solubility: ethanol: 0.93 mg/mL
form: powder
pka: 10.68±0.40(Predicted)
color: white
Stability:: Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: U6881
Product name: U-73343
Packaging: 1mg
Price: $167
Updated: 2024/03/01

Sigma-Aldrich

Product number: 662041
Product name: U-73343
Packaging: 5mg
Price: $172
Updated: 2024/03/01

Cayman Chemical

Product number: 17339
Product name: U-73343
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17339
Product name: U-73343
Purity: ≥95%
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Sigma-Aldrich

Product number: U6881
Product name: U-73343
Packaging: 5mg
Price: $309
Updated: 2024/03/01

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U-73343 Chemical Properties,Usage,Production

Description

U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3?Cell permeable.

Uses

U-73343 is an inactive structural analog of U-73122.

General Description

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at RT

References

1) Bleasdale?et al. (1990),?Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils; J. Pharmacol. Exp. Ther.,?255?756 2) Morley?et al. (1992),?A new, nongenomic estrogen action: the rapid release of intracellular calcium; Endocrinology,131?1305 3) Muto?et al. (1997),?The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell; J. Pharmacol. Exp. Ther.,?282?1379

U-73343 Preparation Products And Raw materials

Raw materials

Preparation Products

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U-73343 Suppliers

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142878-12-4, U-73343Related Search:

Citicoline sodium Phosphatidylinositol (Soy) SodiuM 2-Heptadecanone 2-(P-AMYLCINNAMOYL)AMINO-4-CHLOROBENZOIC ACID OLEYLOXYETHYL PHOSPHORYLCHOLINE BROMOENOL LACTONE Thioetheramide PC UMBELLIFERYL ARACHIDONATE LUFFARIELLOLIDE 73343, Electrolytic tough pitch copper ( O) N,N'-DI-N-BUTYL-1,6-HEXANEDIAMINE CHEMBRDG-BB 4024874 U-73343 1-Pentyl-2-Pyrrolidone N-butylcyclopentanamine 1-HEXYL-PYRROLIDIN-2-ONE N-AMYLSUCCINIMIDE N-BUTYLSUCCINIMIDE

U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE

1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE

U-73343

1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione

3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene

U73343, U-73343, U 73343

U-73343 - CAS 142878-12-4 - Calbiochem

2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-

U-73343,Inhibitor,U73343,Phospholipase,inhibit

142878-12-4

APIS