ChemicalBook > CAS DataBase List > Ethyl 4-chloroacetoacetate

Ethyl 4-chloroacetoacetate

Product Name
Ethyl 4-chloroacetoacetate
CAS No.
638-07-3
Chemical Name
Ethyl 4-chloroacetoacetate
Synonyms
ETHYL 4-CHLORO-3-OXOBUTANOATE;Ethyl 4-chloro-3-oxobutyrate;oroacetoacetate;AKOS BBS-00004336;Ethyl 4-chloroacetoa;4-Chloro-acetoacetic;Amlodipine Impurity R;Amlodipine Impurity 66;Oxiracetam Impurity 15;Ethyl-4-chloracetoacetat
CBNumber
CB2424408
Molecular Formula
C6H9ClO3
Formula Weight
164.59
MOL File
638-07-3.mol
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Ethyl 4-chloroacetoacetate Property

Melting point:
-8 °C
Boiling point:
115 °C/14 mmHg (lit.)
Density 
1.218 g/mL at 25 °C (lit.)
vapor pressure 
7hPa at 20℃
refractive index 
n20/D 1.452(lit.)
Flash point:
206 °F
storage temp. 
2-8°C
solubility 
47.0g/l
form 
Liquid
pka
9.56±0.46(Predicted)
color 
Clear colorless to pale reddish-yellow
PH
2.9 (10g/l, H2O, 20℃)
explosive limit
1.8%(V)
Water Solubility 
47.5 g/L (20 ºC)
BRN 
1761275
InChIKey
OHLRLMWUFVDREV-UHFFFAOYSA-N
LogP
0.68 at 25℃
CAS DataBase Reference
638-07-3(CAS DataBase Reference)
NIST Chemistry Reference
Butanoic acid, 4-chloro-3-oxo-, ethyl ester(638-07-3)
EPA Substance Registry System
Ethyl 4-chloroacetoacetate (638-07-3)
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Safety

Hazard Codes 
T,N,C
Risk Statements 
25-34-51/53-24/25-36
Safety Statements 
26-36-45-61-36/37/39-27
RIDADR 
UN 2922 8/PG 2
WGK Germany 
3
RTECS 
AK5110000
F 
8-10-19-21
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29183000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
180769
Product name
Ethyl 4-chloroacetoacetate
Purity
95%
Packaging
50g
Price
$57.4
Updated
2024/03/01
Sigma-Aldrich
Product number
180769
Product name
Ethyl 4-chloroacetoacetate
Purity
95%
Packaging
250g
Price
$117
Updated
2024/03/01
TCI Chemical
Product number
C0911
Product name
Ethyl 4-Chloroacetoacetate
Purity
>95.0%(GC)
Packaging
25g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
C0911
Product name
Ethyl 4-Chloroacetoacetate
Purity
>95.0%(GC)
Packaging
500g
Price
$160
Updated
2024/03/01
Alfa Aesar
Product number
A15641
Product name
Ethyl 4-chloroacetoacetate, 97%
Packaging
50g
Price
$32.65
Updated
2024/03/01
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Ethyl 4-chloroacetoacetate Chemical Properties,Usage,Production

Chemical Properties

Ethyl 4-chloroacetoacetate is colorless to pale reddish-yellow clear liquid

Uses

Ethyl-4-chloracetoacetate (CAAEt) is used as intermediate for organic syntheses, e.g. ethyl 4-chloro-3-arylaminocrotonates, diethyl succinylsuccinate, 2-alkyl-4-hydroxy-6-chloromethylpyrimidines, 4- chloromethylcoumarines. Product Data Sheet

Uses

Ethyl 4-chloroacetoacetate is used as a precursor in the preparation of phosphorous ylides. It finds application in regular film coating, pharmaceutical coating and formulation.

Ethyl 4-chloroacetoacetate Preparation Products And Raw materials

Raw materials

Acetyl ketene Ethanol Chlorine METHANE

Preparation Products

4-CHLOROMETHYL-7-METHOXY-CHROMEN-2-ONE ETHYL 2-(CHLOROMETHYL)-4-METHYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE 4-CHLOROMETHYL-6-METHYL-CHROMEN-2-ONE 2-(6-METHOXY-1-BENZOFURAN-3-YL)ACETIC ACID
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Ethyl 4-chloroacetoacetate Suppliers

Americas 1 Belgium 4 Brazil 1 Canada 1 China 442 Europe 5 France 1 Germany 10 India 38 Japan 5 Slovakia 1 South Korea 1 Switzerland 5 Ukraine 1 United Kingdom 13 United States 37 Global 567
Pure Chemistry Scientific Inc.
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View Lastest Price from Ethyl 4-chloroacetoacetate manufacturers

Qingdao RENAS Polymer Material Co., Ltd.
Product
4-Chloroacetoacetic acid ethyl ester 638-07-3
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-08-26
Hebei Yanxi Chemical Co., Ltd.
Product
Ethyl 4-chloroacetoacetate 638-07-3
Price
US $40.00-30.00/KG
Min. Order
1KG
Purity
99.9（%）
Supply Ability
50MT/month
Release date
2024-03-27
airuikechemical co., ltd.
Product
Ethyl 4-Chloroacetoacetate 638-07-3
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08

638-07-3, Ethyl 4-chloroacetoacetateRelated Search:

Ethyl acrylate Ethyl 4,4,4-trifluoroacetoacetate Ethyl acetoacetate Ethyl cyanoacetate Ethylparaben Ethanol Ethyl 2-methylacetoacetate Ethyl 4-bromoacetoacetate Ethyl chloroacetate ISOXADIFEN-ETHYL Trinexapac-ethyl Ethyl propiolate Ethyl acetate 2-Hexenoic acid, 4,5-dihydroxy-, (2E,4S,5R)- 2-Hexenoic acid, 4,5-dihydroxy- 1-Butanaminium, 4-methoxy-N,N,N-trimethyl-2,4-dioxo-, chloride (1:1) 4-CHLORO-3-ETHOXY-BUT-2-ENOIC ACID ETHYL ESTER Ethyl2-chloroacetoacetate,97%,ETHYL 2-CHLOROACETOACETATE,ETHYL ALPHA-CHLOROACETOACETATE,ETHYL 2-CHLOROACETOACETATE, WACKERQUALIT Y

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