Cytidine 5'-monophosphate disodium salt

ChemicalBook > CAS DataBase List > Cytidine 5'-monophosphate disodium salt

Cytidine 5'-monophosphate disodium salt

Uses

Product Name: Cytidine 5'-monophosphate disodium salt
CAS No.: 6757-06-8
Chemical Name: Cytidine 5'-monophosphate disodium salt
Synonyms: CMP-2Na;CMP, NA2;5'-CMP 2NA;5'-cmp-na2;C-5μ-P, CMP;CMP DISODIUM SALT;C-5'-P DISODIUM SALT;Cytidine 5'-monophos;Guanosine 5'-cytidine;Disodium 5’-cytidylate
CBNumber: CB2441544
Molecular Formula: C9H15N3NaO8P
Formula Weight: 347.2
MOL File: 6757-06-8.mol

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Cytidine 5'-monophosphate disodium salt Property

Melting point:: 300 °C
refractive index: 8 ° (C=2, H2O)
storage temp.: 2-8°C
form: crystalline
color: White
InChI: InChI=1/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;/t4-,6-,7-,8-;;/s3
InChIKey: RCIPNLSOCXMZDD-RFFBCSJBNA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,11,r|
CAS DataBase Reference: 6757-06-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-37/39-36-26
WGK Germany: 3
F: 1-10
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C1006
Product name: Cytidine 5′-monophosphate disodium salt
Purity: Sigma Grade, ≥99%, crystalline
Packaging: 500MG
Price: $48.9
Updated: 2023/06/20

Sigma-Aldrich

Product number: C1006
Product name: Cytidine 5′-monophosphate disodium salt
Purity: Sigma Grade, ≥99%, crystalline
Packaging: 1G
Price: $59.3
Updated: 2023/06/20

Sigma-Aldrich

Product number: C1006
Product name: Cytidine 5′-monophosphate disodium salt
Purity: Sigma Grade, ≥99%, crystalline
Packaging: 5G
Price: $159
Updated: 2023/06/20

TCI Chemical

Product number: C0524
Product name: Cytidine 5'-Monophosphate Disodium Salt Hydrate
Purity: >99.0%(HPLC)
Packaging: 1g
Price: $17
Updated: 2024/03/01

TCI Chemical

Product number: C0524
Product name: Cytidine 5'-Monophosphate Disodium Salt Hydrate
Purity: >99.0%(HPLC)
Packaging: 5g
Price: $26
Updated: 2024/03/01

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Cytidine 5'-monophosphate disodium salt Chemical Properties,Usage,Production

Uses

Cytidine 5'-Monophosphate Disodium Salt is a salt form of Cytidine 5'-Monophosphate, a constituent of nucleic acids that has been isolated from yeast nucleic acid.

Description

Cytidine 5'-monophosphate disodium salt (5'-CMPNa2) is an organic sodium salt that can be used as a pharmaceutical active ingredient. 5'-CMPNa2 can be used with UMP-Na2, vitamin B6, lipoic acid, and magnesium lactate dihydrate to prepare a capsule-type compound drug for the treatment of polyneuropathy[1].

Chemical Properties

White crystalline powder

Uses

Cytidine 5′-monophosphate disodium salt has been used:

in nucleotide stock solution
as an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neurons
in in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine

Production Methods

The production method of Cytidine 5'-monophosphate disodium salt comprises the following steps: a. adding cytidine, triethyl phosphate and pyridine into a reaction container respectively, and adjusting the reaction temperature to -15-5°C after mixing evenly, and slowly adding a certain amount of phosphorus oxychloride under the temperature condition, and continuing to stir and react for 10-30h after adding; b. taking samples for HPLC analysis, and when the conversion rate is ≥99%, adding 10-15% ice salt water for hydrolysis, and the hydrolysis temperature is controlled to be 0-5°C, and the hydrolysis time is 10-20h; c. after the hydrolysis is completed, standing and stratifying, removing the organic phase, and obtaining a water layer for standby use; d. adjusting the pH of the water layer to 7.0-8.0 with 30% sodium hydroxide, and then dripping 95% alcohol twice the volume of the solution, precipitating crystals, and filtering to obtain a crude product. e. dissolving the crude product, adding activated carbon for decolorization, and continuing to drip 95% alcohol twice the volume of the solution to precipitate crystals, filtering, rinsing, and drying to obtain the finished product Cytidine 5'-monophosphate disodium salt.

Definition

ChEBI: An organic sodium salt that is the disodium salt of CMP.

Biochem/physiol Actions

Cytidine monophosphate?(CMP) serve as a nucleotide?carrier for sugars.

References

[1] M. ALMAKAIEV L. S O Bashura. The risk assessment of the combined medicine in the capsule dosage form at the pharmaceutical development stage[J]. News of Pharmacy, 2021. DOI:10.24959/nphj.21.54.

Cytidine 5'-monophosphate disodium salt Preparation Products And Raw materials

Raw materials

Ribonucleic acid

Preparation Products

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View Lastest Price from Cytidine 5'-monophosphate disodium salt manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Cytidine 5'-Monophosphate Disodium Salt;CMP-Na2;5'-CMP-Na2 6757-06-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.0%min. HPLC
Supply Ability: 1000kg
Release date: 2024-09-11

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Cytidine 5'-monophosphate disodium salt 6757-06-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 500kg
Release date: 2022-05-24

Hebei Weibang Biotechnology Co., Ltd

Product: Cytidine 5’-monophosphate disodium salt 6757-06-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-05

6757-06-8, Cytidine 5'-monophosphate disodium saltRelated Search:

Sodium Monofluorophosphate Cytidine-5'-triphosphate disodium salt dihydrate 5-Azacytidine Cytidine Disodium hydrogen phosphate dihydrate Pamidronate disodium salt Ethylenediaminetetraacetic acid disodium salt Clodronate disodium Cytarabine 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 2'-Deoxycytidine-5'-monophosphate disodium salt Cytidine 5’-monophosphate 2'-Deoxycytidine-5'-monophosphoric acid 2',3'-Dideoxycytidine 5'-monophosphate CYTIDINE 5'-MONOPHOSPHATE SODIUM SALT Cytidine 5'-monophosphate disodium salt CYTIDINE-5'-MONOPHOSPHATE DISODIUM SALT HEXAHYDRATE CYTIDINE-5'-MONOPHOSPHATE SODIUM SALT, [5'-3H]

5'-CMP 2NA

5'-CYTIDYLIC ACID DISODIUM SALT

CYTIDYLIC ACID DISODIUM SALT

CYTIDINE-5'-MONOPHOSPHATE SODIUM SALT

CYTIDINE-5'-MONOPHOSPHATE DISODIUM SALT

CYTIDINE 5'-PHOSPHATE, SODIUM SALT

CYTIDINE-5'-MONOPHOSPHORIC ACID, DISODIUM

CMP, NA2

CMP DISODIUM SALT

C-5'-P DISODIUM SALT

Disodium 5'-cytidine (cytosine sodium)

Cytidine 5'-(disodium phosphate),Disodiumsalt

CYTIDINE-5'-MONOPHOSPHATE DISODIUM SALT(SH)

Cytidine 5'-monophosphate, disodium

disodium cytidine 5'-monophosphate

disodium [(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

Cytidine-5'-Monophosphoric Acid Disodium Salt

CYTIDINE 5'-MONOPHOSPHATE DISODIUMSIGMA GRADE

5'-cmp-na2

Cytidine-5'monohposphate Disodium Salt

CMP-2Na

Cytidine 5'-monophosphate(CMP),2Na

5μ-CMP-Na2, 5μ-Cytidylic acid disodium salt

Cytidine 5μ-monophosphate hydrate disodium salt

C-5μ-P, CMP

Disodium 5’-cytidylate

Cytidine 5'-monophosphate, disodium salt hydrate,96%

Cytidine 5'-monophos

SodiuM ((2R,3S,4R,5R)-5-(4-aMino-2-oxopyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl phosphate

5'-Cytidylic Acid Disodium Salt 5'-CMP 2Na

Cytidine -5'- Monophosphate Disodium Salt（CMP- Na2）

CYTIDINE-5’- MONOPHOSPHAT DISODIUM SALT(CMP)

Cytidine-5-' disodium monophosphate

Guanosine 5'-cytidine

TIANFUCHEM-- 6757-06-8--Cytidine 5'-monophosphate disodium salt factory price

Disodium 5 '- cytidine

5'-Cytidine-5’monohposphate Disodium Salt

Cytidine5'-monophosphatedisodiumsal

Cytidine -5'- monophosphate disodium salt(CMP-Na,)

Cytidine 5'-monophosphate disodium salt

5'-Cytidine-5’monohposphate Disodium Salt

Cytidine 5''-monophosphate disodium salt

Cytidine 5'-(disodium phosphate)

CYTIDINE 2'-MONOPHOSPHATE

Cytidine 5'-monophosphate, disodium

6757-06-8

6757-6-8

1774-14-3

675-76-8

C9H12N3Na2O8PxxH2O

C9H12N3O8PNa2

C9H12N3Na4O14P3

C9H12N3Na2O8P2H2O

C9H12N3Na2O8P

C9H12N3Na2O8PxH2O

Nucleotide Analogs

Nucleosides, Nucleotides, Oligonucleotides

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