1-(4-Bromo-2-fluorophenyl)ethanone

Product Name: 1-(4-Bromo-2-fluorophenyl)ethanone
CAS No.: 625446-22-2
Chemical Name: 1-(4-Bromo-2-fluorophenyl)ethanone
Synonyms: 2-Fluoro-4-bromoacetophenone;4-BROMO-2-FLUOROACETOPHENONE;4'-Bromo-2'-fluoroacetophenone;1-Acetyl-4-bromo-2-fluorobenzene;4'-Bromo-2'-fluoroacetophenone98%;4'-Bromo-2'-fluoroacetophenone 98%;4'-Bromo-2'-fluoroacetophenone,96%;1-(4-bromo-2-fluorophenyl)ethanone;Ethanone, 1-(4-broMo-2-fluorophenyl)-;1-(4-broMophenyl)-2-fluoroethan-1-one
CBNumber: CB2470687
Molecular Formula: C8H6BrFO
Formula Weight: 217.04
MOL File: 625446-22-2.mol

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1-(4-Bromo-2-fluorophenyl)ethanone Property

Melting point:: 23 °C
Boiling point:: 256.3±25.0 °C(Predicted)
Density: 1.535±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Acetonitrile (Slightly), Chloroform (Slightly)
form: Solid
color: White to Off-White
InChI: InChI=1S/C8H6BrFO/c1-5(11)7-3-2-6(9)4-8(7)10/h2-4H,1H3
InChIKey: ASKFCSCYGAFWAB-UHFFFAOYSA-N
SMILES: C(=O)(C1=CC=C(Br)C=C1F)C

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-36
Safety Statements: 26-36/37/39
Hazard Note: Irritant
HS Code: 2914790090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SYX00307
Product name: 4-Bromo-2-fluoroacetophenone
Packaging: 1g
Price: $185
Updated: 2025/07/31

TCI Chemical

Product number: B5236
Product name: 4'-Bromo-2'-fluoroacetophenone
Purity: >98.0%(GC)
Packaging: 1g
Price: $67
Updated: 2025/07/31

TCI Chemical

Product number: B5236
Product name: 4'-Bromo-2'-fluoroacetophenone
Purity: >98.0%(GC)
Packaging: 5g
Price: $198
Updated: 2025/07/31

TRC

Product number: A168813
Product name: 1-Acetyl-4-bromo-2-fluorobenzene
Packaging: 1g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2617-B-X2
Product name: 4'-Bromo-2'-fluoroacetophenone
Purity: 98%
Packaging: 1g
Price: $85
Updated: 2021/12/16

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1-(4-Bromo-2-fluorophenyl)ethanone Chemical Properties,Usage,Production

Synthesis

To a solution of 4-bromo-2-fluoro-N-methoxy-N-methylbenzamide (13 g, 46 mmol) in THF (4.0 mL) was added dropwise methylmagnesium bromide (3M ethyl ether solution, 30 mL, 91 mmol) at 0°C, and the mixture was stirred at room temperature for 3 hr. For the reaction mixture, saturated aqueous ammonium chloride solution, and the mixture was extracted with ethyl acetate. The obtained extract was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give 4-Bromo-2-fluoroacetophenone as a pale yellow oil.

References

[1] Patent: US2008/45556, 2008, A1. Location in patent: Page/Page column 32
[2] Patent: US2011/118257, 2011, A1. Location in patent: Page/Page column 97-98
[3] Patent: US2011/281865, 2011, A1. Location in patent: Page/Page column 85-86
[4] Patent: WO2011/145035, 2011, A1. Location in patent: Page/Page column 114-115
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 2, p. 282 - 297

1-(4-Bromo-2-fluorophenyl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-Bromo-2-fluorophenyl)ethanone Suppliers

Americas 1 China 170 Europe 1 Germany 2 India 3 Italy 1 Japan 1 United Kingdom 6 United States 14 Global 199

Accela ChemBio Inc.

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Marshallton Research Laboratories Inc.

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View Lastest Price from 1-(4-Bromo-2-fluorophenyl)ethanone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1-(4-Bromo-2-fluorophenyl)ethanone 625446-22-2
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99% min
Supply Ability: 100kg
Release date: 2025-08-18

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4'-Bromo-2'-fluoroacetophenone 625446-22-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-22

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-BROMO-2-FLUOROACETOPHENONE 625446-22-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

625446-22-2, 1-(4-Bromo-2-fluorophenyl)ethanoneRelated Search:

3'-Bromo-4'-fluoroacetophenone97%,3- BROMO-4-FLUOROACETOPHENONE 98+%,3-BROMO-4-FLUOROACETOPHENONE,3'-BROMO-4'-FLUOROACETOPHENONE ALPHA,ALPHA-DIBROMO-4-FLUOROACETOPHENONE ALPHA-BROMO-3-FLUOROACETOPHENONE,2-BROMO-3'-FLUOROACETOPHENONE 2'-BROMO-5'-FLUOROACETOPHENONE 2-BROMO-2'-FLUOROACETOPHENONE 2-Bromo-4'-fluoroacetophenone 2'-Bromo-4'-fluoroacetophenone 97%,2'-Bromo-4'-fluoroacetophenone97% 3'-Bromo-2'-Fluoroacetophenone 1-(4-Bromo-2-fluorophenyl)ethanone 4-BROMO-2-FLUORO-3'-PYRROLIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-3'-PIPERIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-THIOMORPHOLINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-PYRROLIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUOROPHENYL CYCLOPENTYL KETONE 4-BROMO-2-FLUOROPHENYL CYCLOPROPYL KETONE 4'-BROMO-2,2-DIMETHYL-2'-FLUOROPROPIOPHENONE 4-BROMO-2-FLUORO-3'-MORPHOLINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-MORPHOLINOMETHYL BENZOPHENONE

1-Acetyl-4-bromo-2-fluorobenzene

1-(4-Bromo-2-fluorophenyl)ethan-1-one

1-(4-broMophenyl)-2-fluoroethan-1-one

Ethanone, 1-(4-broMo-2-fluorophenyl)-

4-Bromo-2-fluoroacetophenone/2-Fluoro-4-bromoacetophenone

4'-Bromo-2'-fluoroacetophenone 98%

4'-Bromo-2'-fluoroacetophenone98%

4-BROMO-2-FLUOROACETOPHENONE

2-Fluoro-4-bromoacetophenone

4'-Bromo-2'-fluoroacetophenone,96%

4'-Bromo-2'-fluoroacetophenone

1-(4-bromo-2-fluorophenyl)ethanone

625446-22-2

625446-22-5

Fluorine series

Adehydes, Acetals & Ketones

Bromine Compounds

Fluorine Compounds