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TYRPHOSTIN AG 835

Product Name
TYRPHOSTIN AG 835
CAS No.
133550-37-5
Chemical Name
TYRPHOSTIN AG 835
Synonyms
AG 835;TYRPHOSTIN B50;(+)-Enantiomer;TYRPHOSTIN B50(+);TYRPHOSTIN AG 835;(+)-Tyrphostin B44;TYRPHOSTIN B44, (+) ENANTIOMER;Tyrphostin B44, (+) enantiomer AG835;(S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide;ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE
CBNumber
CB2472555
Molecular Formula
C18H16N2O3
Formula Weight
308.33
MOL File
133550-37-5.mol
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TYRPHOSTIN AG 835 Property

Melting point:
146 °C
Boiling point:
603.0±55.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO or ethanol: soluble
form 
powder to crystal
pka
8.81±0.10(Predicted)
color 
Light yellow to Amber to Dark green
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2926.90.4801
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H371May cause damage to organs

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3540
Product name
Tyrphostin AG 835
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
T3540
Product name
Tyrphostin AG 835
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$304
Updated
2024/03/01
Tocris
Product number
0579
Product name
TyrphostinB44,(+)enantiomer
Packaging
50
Price
$465
Updated
2021/12/16
Tocris
Product number
0579
Product name
TyrphostinB44,(+)enantiomer
Packaging
10
Price
$111
Updated
2021/12/16
TRC
Product number
T947985
Product name
TyrphostinB44,(+)enantiomer
Packaging
5mg
Price
$45
Updated
2021/12/16
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TYRPHOSTIN AG 835 Chemical Properties,Usage,Production

Uses

Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor.

Biological Activity

Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ).

TYRPHOSTIN AG 835 Preparation Products And Raw materials

Raw materials

Preparation Products

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TYRPHOSTIN AG 835 Suppliers

China 29 Europe 1 Germany 3 India 1 Japan 1 Switzerland 2 United Kingdom 5 United States 12 USA 1 Global 55
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74

133550-37-5, TYRPHOSTIN AG 835Related Search:

AG 99 TYRPHOSTIN AG 126 AG 18 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) TYRPHOSTIN AG 528 TYRPHOSTIN B48 TYRPHOSTIN A1 TYRPHOSTIN A9 AG 490 N-ISOPROPYLMETHACRYLAMIDE BENZYL-((E)-3-PHENYL-ALLYL)-AMINE AG 99 3-(1-PHENYLETHYLAMINO)PROPANENITRILE D,L-N-(ALPHA-PHENYLETHYL) METHACRYLAMIDE N1-ISOPROPYL-2-CYANOACETAMIDE TYRPHOSTIN AG 835 TYRPHOSTIN B44

  • AG 835
  • ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE
  • (S)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE
  • (+)-(S)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
  • TYRPHOSTIN B44, (+) ENANTIOMER
  • TYRPHOSTIN AG 835
  • TYRPHOSTIN B50
  • TYRPHOSTIN B50(+)
  • (+)-Enantiomer
  • (+)-(s)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
  • Tyrphostin B44, (+) enantiomer AG835
  • Tyrphostin B50, (+)-(S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
  • (2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide
  • (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide
  • 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-, (2E)-
  • (S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide
  • (+)-Tyrphostin B44
  • non-metastatic tumors,INBL,antitumor,(+)-Tyrphostin B44,Epidermal growth factor receptor,Tyrphostin B50,ErbB-1,Tyrphostin B-44, (+) enantiomer,Inhibitor,Tyrphostin B 50,CALO,cervical carcinoma cell,EGFR,inhibit,Tyrphostin B44, (+) enantiomer,Tyrphostin AG835,HER1,Tyrphostin AG-835,Tyrphostin AG 835,Tyrphostin B-50
  • (S,E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide
  • 133550-37-5
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Receptor Tyrosine Kinase Inhibitors
  • Kinase/Phosphatase Biology
  • Epidermal Growth Factor Receptor (EGFR)
  • Protein Kinase