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NOC-5

Product Name
NOC-5
CAS No.
146724-82-5
Chemical Name
NOC-5
Synonyms
NOC 5;NOC-5;NOC 5,NOC5;3-(aminopropyl)-1-hydr;3-(aminopropyl)-1-hydroxy-3-isopropyl-*2-oxo-1-tr;3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2- OXO-1-TRIA;3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2-OXO-1-TRIAZENE;1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-ISOPROPYL-1-TRIAZENE;3-(2-Hydroxy-1-isopropyl-2-nitrosohydrazino)-propylamine;N-[3-aminopropyl(propan-2-yl)amino]-N-hydroxynitrous amide
CBNumber
CB2477303
Molecular Formula
C6H16N4O2
Formula Weight
176.22
MOL File
146724-82-5.mol
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NOC-5 Property

storage temp. 
-20°C
solubility 
Water
form 
White solid
color 
White
Water Solubility 
0.1 M NaOH: soluble
water: soluble
Stability:
Store at -20°C, Light and Moisture Sensitive
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H242Heating may cause a fire

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A5456
Product name
NOC-5
Purity
≥95%
Packaging
10mg
Price
$248.9
Updated
2025/07/31
Sigma-Aldrich
Product number
487950
Product name
NOC-5 - CAS 146724-82-5 - Calbiochem
Purity
A nitric oxide (NO) donor.
Packaging
10MG
Price
$179
Updated
2022/05/15
Cayman Chemical
Product number
16534
Product name
NOC-5
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
16534
Product name
NOC-5
Purity
≥98%
Packaging
5mg
Price
$97
Updated
2024/03/01
Cayman Chemical
Product number
16534
Product name
NOC-5
Purity
≥98%
Packaging
10mg
Price
$172
Updated
2024/03/01
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NOC-5 Chemical Properties,Usage,Production

Description

NOC-5 is a stable nitric oxide (NO)-amine complex that acts as a NO donor. It can release two equivalents of NO in solution under physiological conditions without a cofactor. The half-life of NOC-5 in PBS (pH 7.4) is 93 minutes at 22°C, and it remains relatively stable in alkaline solution (pH ≥10.0).

Chemical Properties

White Powder

Uses

A stable NO-amine complex which can release NO spontaneously under physiological conditions. The half life of NO release in 0.1 M PBS at (pH7.4) at 37?C for 0.1mM NOC 5 is 25 minutes.

Uses

Releases nitric oxide spontaneously in a rate-controlled manner; half life in solution = 93 min.

Definition

ChEBI: NOC-5 is a nitroso compound that is triazane in which the nitrogen at position 1 is substituted by an isopropyl group and a 3-aminopropyl group, that at position 2 is substituted by a hydroxy group, and that at position 3 is substituted by an oxo group. It is a nitric oxide donor. It has a role as a nitric oxide donor. It is a nitroso compound, a tertiary amino compound and a primary amino compound.

References

[1] JOSEPH A. HRABIE. New nitric oxide-releasing zwitterions derived from polyamines[J]. The Journal of Organic Chemistry, 1993, 58 6: 1472-1476. DOI: 10.1021/jo00058a030

NOC-5 Preparation Products And Raw materials

Raw materials

Preparation Products

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NOC-5 Suppliers

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146724-82-5, NOC-5Related Search:

NOC-5 NOC-7 NOC-12 2,2μ-(Hydroxynitrosohydrazino)bis-ethanamine, DETA NONOate, NOC-18,DETA-NONOate,NOC-18,NOC 18, DETA NONOate,,NOC-18 NOC-D-HOMOPRO-OH 3-(2-Hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine, NOC-15,NOC-15 NONOATE,NOC-15 NOC-22 NOC-9, 6-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-hexanamine,NOC-9,noc-9crystalline NOC DOTA-NOC, DOTA-[Nal3]-octreotide,DOTA-NOC Noc3 protein Noc2 protein, nucleolar NOC-12 (DRY ICE) Noc2 protein NOC 18 (F-G)NOC oFQ(1-13)-NH2 1-HYDROXY-2-OXO-3,3-BIS(2-AMINO ETHYL)-1-TRIAZENE (NOC-18) Noc1 protein

  • NOC-5
  • 3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2-OXO-1-TRIAZENE
  • 1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-ISOPROPYL-1-TRIAZENE
  • 3-(aminopropyl)-1-hydr
  • 3-[2-Hydroxy-1-(1-Methylethyl)-2-Nitrosohydrazino]-1-Propanamine Discontinued
  • 3-[2-HYDROXY-1-(1-METHYLETHYL)-2-NITROSOHYDRAZINO]-1-PROPANAMINE
  • NOC 5
  • 3-(aminopropyl)-1-hydroxy-3-isopropyl-*2-oxo-1-tr
  • 3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2- OXO-1-TRIA
  • 3-(2-Hydroxy-1-isopropyl-2-nitrosohydrazino)-propylamine
  • N-[3-aminopropyl(propan-2-yl)amino]-N-hydroxynitrous amide
  • 1-Propanamine, 3-[2-hydroxy-1-(1-methylethyl)-2-nitrosohydrazinyl]-
  • NOC 5,NOC5
  • 146724-82-5
  • Cell Signaling Enzymes
  • Biochemicals and Reagents
  • Application Index
  • BioChemical
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide Metabolism
  • NO Donors
  • Nitric Oxide Reagents