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Suprofen

Product Name
Suprofen
CAS No.
40828-46-4
Chemical Name
Suprofen
Synonyms
Suprol;TN 762;r25061;Anemet;Srendam;Suprocil;Topalgic;Profenal;Profenol;maldocil
CBNumber
CB2496867
Molecular Formula
C14H12O3S
Formula Weight
260.31
MOL File
40828-46-4.mol
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Suprofen Property

Melting point:
278°C
Boiling point:
373.57°C (rough estimate)
Density 
1.2959 (rough estimate)
refractive index 
1.5050 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka
3.91(at 25℃)
form 
Powder
Water Solubility 
soluble
CAS DataBase Reference
40828-46-4(CAS DataBase Reference)
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Safety

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2934990002
Toxicity
LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1495
Product name
Suprofen
Purity
≥98% (HPLC)
Packaging
5MG
Price
$80.7
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1495
Product name
Suprofen
Purity
≥98% (HPLC)
Packaging
25MG
Price
$261
Updated
2024/03/01
Sigma-Aldrich
Product number
1642507
Product name
Suprofen
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200MG
Price
$252
Updated
2024/03/01
Cayman Chemical
Product number
21350
Product name
Suprofen
Purity
≥98%
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
21350
Product name
Suprofen
Purity
≥98%
Packaging
10mg
Price
$115
Updated
2024/03/01
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Suprofen Chemical Properties,Usage,Production

Description

Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.

Chemical Properties

Off-White to Light-Brown

Originator

Janssen (Belgium)

Uses

Prostaglandin biosynthesis inhibitor. Analgesic

Uses

Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.

Definition

ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.

brand name

Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.

Veterinary Drugs and Treatments

Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).

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Suprofen Suppliers

Sangel Pharmaceutical & Chemical Factory
Tel
0571-0571-85773987 13505717485
Fax
+86057185773986
Email
1610413282@qq.com
Country
China
ProdList
70
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
24835
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
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View Lastest Price from Suprofen manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Suprofen 40828-46-4
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Suprofen 40828-46-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%-102%
Supply Ability
100G
Release date
2021-06-09
Hebei Mojin Biotechnology Co., Ltd
Product
Suprofen 40828-46-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-01

40828-46-4, SuprofenRelated Search:


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  • 40828-46-4
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  • Inhibitors
  • Heterocyclic Compounds
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  • Intermediates & Fine Chemicals
  • Pharmaceuticals