ChemicalBook > CAS DataBase List > Suprofen

Suprofen

Product Name
Suprofen
CAS No.
40828-46-4
Chemical Name
Suprofen
Synonyms
Suprol;TN 762;r25061;Anemet;Srendam;Suprocil;Topalgic;Profenal;Profenol;maldocil
CBNumber
CB2496867
Molecular Formula
C14H12O3S
Formula Weight
260.31
MOL File
40828-46-4.mol
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Suprofen Property

Melting point:
278°C
Boiling point:
373.57°C (rough estimate)
Density 
1.2959 (rough estimate)
refractive index 
1.5050 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka
3.91(at 25℃)
form 
Powder
color 
White to off-white
Water Solubility 
soluble
CAS DataBase Reference
40828-46-4(CAS DataBase Reference)
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Safety

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2934990002
Toxicity
LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1495
Product name
Suprofen
Purity
≥98% (HPLC)
Packaging
5MG
Price
$80.7
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1495
Product name
Suprofen
Purity
≥98% (HPLC)
Packaging
25MG
Price
$261
Updated
2024/03/01
Sigma-Aldrich
Product number
1642507
Product name
Suprofen
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200MG
Price
$252
Updated
2024/03/01
Cayman Chemical
Product number
21350
Product name
Suprofen
Purity
≥98%
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
21350
Product name
Suprofen
Purity
≥98%
Packaging
10mg
Price
$115
Updated
2024/03/01
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Suprofen Chemical Properties,Usage,Production

Description

Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.

Chemical Properties

Off-White to Light-Brown

Originator

Janssen (Belgium)

Uses

Prostaglandin biosynthesis inhibitor. Analgesic

Uses

Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.

Definition

ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.

brand name

Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.

Veterinary Drugs and Treatments

Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).

Suprofen Preparation Products And Raw materials

Raw materials

Osmium tetroxide dolasetron Dihydropyran 4-METHYLMORPHOLINE-4-OXIDE SOLUTION Sodium borohydride Silver tetrafluoroborate Double ring Sodium periodate ethyl cyclopent-3-ene-1-carboxylate Furan

Preparation Products

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Suprofen Suppliers

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View Lastest Price from Suprofen manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Suprofen 40828-46-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%-102%
Supply Ability
100G
Release date
2021-06-09
Hebei Weibang Biotechnology Co., Ltd
Product
Suprofen 40828-46-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-20
Career Henan Chemica Co
Product
Suprofen 40828-46-4
Price
US $1.00/g
Min. Order
1g
Purity
85.0-99.8%
Supply Ability
20tons
Release date
2020-10-28

40828-46-4, SuprofenRelated Search:

Flurbiprofen (S)-(+)-2-Phenylpropionic acid Thifensulfuron Propionic acid Cephalothin sodium Tetrahydrothiophene 4-Methoxyphenylacetone Suprofen-D3 LC-R 505 Cliprofen Suprofen SUPROFEN USP(CRM STANDARD) suprofen acyl glucuronide (S)-(+)-Suprofen,(S)-Suprofen suprofen-copper(II) complex (R)-Suprofen,R(-)-Suprofen Dearboxy suprofen 4-((5-Bromo-2-thienyl)carbonyl)-alpha-methylbenzeneacetic acid

  • Dolasetron Methanesulformte
  • MDL-73147EF：Anzemet
  • 2-[4-(Thiophene-2-carbonyl)phenyl]propanoic acid
  • a-Methyl-p-(2-thenoyl)phenylacetic acid
  • 2-[4-(thiophene-2-carbonyl)phenyl]propionic acid
  • 1H-Indole-3-carboxylic acid(2α，6α，8α，9αβ)-octahydro-3-oxo-2，6-methano-2H-quinolizin-8-yl ester
  • Suprofen (200 mg)
  • α-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid
  • para-(2-Thenoyl) hydratropic acid
  • Maldocil,Masterfen,Supranol,Supro,
  • a-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid
  • Masterfen
  • Srendam
  • Sulprotin
  • Suprocil
  • Suprol
  • Sutoprofen
  • Topalgic
  • DOLASETRON(FREE BASE)
  • Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)- (9CI)
  • NSC 303611
  • Profenal
  • Profenol
  • Racemic suprofen
  • Sulproltin
  • TN 762
  • (+-)-2-(p-(2-thenoyl)phenyl)propionicacid
  • alpha-methyl-4-(2-thienylcarbonyl)-benzeneaceticaci
  • alpha-methyl-4-(2-thienylcarbonyl)benzeneaceticacid
  • maldocil
  • p-(2-thenoyl)-hydratropicaci
  • p-(2-thenoyl)hydratropicacid
  • r25061
  • Suprofen
  • BENZENEACETICACID,A-METHYL-4-(2-THIENYLCARBONYL)
  • Anemet
  • MDL 73147
  • Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl Ester 1H-Indole-3-carboxylic Acid Stereoisomer
  • 2-(4-Thiophen-2-ylcarbonylphenyl)propanoic acid
  • Benzeneacetic acid, α-methyl-4-(2-thienylcarbonyl)-
  • 2-[4-(2-Thienylcarbonyl)phenyl]propanoic Acid
  • Suprofen USP/EP/BP
  • Suprofen (TN-762)
  • Suprofen (1642507)
  • 2-(3-(Thiophene-2-carbonyl)phenyl)propanoic acid
  • Ranelic Acid Impurity 9
  • 40828-46-4
  • 115952-12-2
  • 115956-12-0
  • Inhibitors
  • Heterocyclic Compounds
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals