Suprofen
- Product Name
- Suprofen
- CAS No.
- 40828-46-4
- Chemical Name
- Suprofen
- Synonyms
- Suprol;TN 762;r25061;Anemet;Srendam;Suprocil;Topalgic;Profenal;Profenol;maldocil
- CBNumber
- CB2496867
- Molecular Formula
- C14H12O3S
- Formula Weight
- 260.31
- MOL File
- 40828-46-4.mol
Suprofen Property
- Melting point:
- 278°C
- Boiling point:
- 373.57°C (rough estimate)
- Density
- 1.2959 (rough estimate)
- refractive index
- 1.5050 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.5 mg/ml
- pka
- 3.91(at 25℃)
- form
- Powder
- color
- White to off-white
- Water Solubility
- soluble
- CAS DataBase Reference
- 40828-46-4(CAS DataBase Reference)
Safety
- RIDADR
- 3249
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2934990002
- Toxicity
- LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers)
N-Bromosuccinimide Price
- Product number
- SML1495
- Product name
- Suprofen
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $80.7
- Updated
- 2024/03/01
- Product number
- SML1495
- Product name
- Suprofen
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $261
- Updated
- 2024/03/01
- Product number
- 1642507
- Product name
- Suprofen
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200MG
- Price
- $252
- Updated
- 2024/03/01
- Product number
- 21350
- Product name
- Suprofen
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 21350
- Product name
- Suprofen
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $115
- Updated
- 2024/03/01
Suprofen Chemical Properties,Usage,Production
Description
Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.
Chemical Properties
Off-White to Light-Brown
Originator
Janssen (Belgium)
Uses
Prostaglandin biosynthesis inhibitor. Analgesic
Uses
Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.
Definition
ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
brand name
Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.
Veterinary Drugs and Treatments
Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).
Suprofen Preparation Products And Raw materials
Raw materials
Preparation Products
Suprofen Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
View Lastest Price from Suprofen manufacturers
- Product
- Suprofen 40828-46-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%-102%
- Supply Ability
- 100G
- Release date
- 2021-06-09
- Product
- Suprofen 40828-46-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- Suprofen 40828-46-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-10-28