CYCLIC-PIFITHRIN-ALPHA

Product Name: CYCLIC-PIFITHRIN-ALPHA
CAS No.: 60477-34-1
Chemical Name: CYCLIC-PIFITHRIN-ALPHA
Synonyms: Pifithrin-2;Pifithrin-alpha (cyclic) . HBr;Pifithrin-β (QB-102 and Cyclic-Pifithrin-α);Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem;2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole;Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
CBNumber: CB2504209
Molecular Formula: C16H16N2S
Formula Weight: 268.38
MOL File: 60477-34-1.mol

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CYCLIC-PIFITHRIN-ALPHA Property

Melting point:: 266.4-267.3 °C(lit.)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: 20 mg/mL
form: White solid
pka: 6.75±0.20(Predicted)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B4813
Product name: Pifithrin-β
Packaging: 5mg
Price: $87
Updated: 2021/12/16

ApexBio Technology

Product number: B4813
Product name: Pifithrin-β
Packaging: 10mg
Price: $148
Updated: 2021/12/16

Axon Medchem

Product number: Axon3051
Product name: Pifithrin-β-PFT-β|Z-2-035II
Purity: 99%
Packaging: 2x10mg
Price: $165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0017104
Product name: PIFITHRIN-B
Purity: 95.00%
Packaging: 5MG
Price: $497.16
Updated: 2021/12/16

ApexBio Technology

Product number: B4813
Product name: Pifithrin-β
Packaging: 50mg
Price: $607
Updated: 2021/12/16

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CYCLIC-PIFITHRIN-ALPHA Chemical Properties,Usage,Production

Definition

ChEBI: 2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole is a member of imidazoles.

General Description

A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.

Biochem/physiol Actions

Cell permeable: yes

CYCLIC-PIFITHRIN-ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLIC-PIFITHRIN-ALPHA Suppliers

China 20 Switzerland 1 United States 8 Global 29

Shanghai Boyle Chemical Co., Ltd.

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MedChemexpress LLC

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Shanghai Tauto Biotech Co., Ltd.

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Sigma-Aldrich

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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai QianYan Bio-technology Co., Ltd

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Tianjin Kailiqi Biotechnology Co., Ltd.

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Shanghai SuperLan Chemcial Technique Centre

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Amadis Chemical Company Limited

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Musechem

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60477-34-1, CYCLIC-PIFITHRIN-ALPHARelated Search:

Pifithrin-α (PFTα) SB 220025 PRIMA-1 PD 169316 FHPI HCL CP 31398 SB 239063 SB 202190 1H-INDOLE-5-CARBOXAMIDE, 97% JX401

Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

Pifithrin-alpha (cyclic) . HBr

5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole

Pifithrin-2

Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-

Pifithrin-β (QB-102 and Cyclic-Pifithrin-α)

2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole

60477-34-1