ChemicalBook > CAS DataBase List > Methyl 3-(4-methoxyphenyl)-3-oxopropionate

Methyl 3-(4-methoxyphenyl)-3-oxopropionate

Product Name
Methyl 3-(4-methoxyphenyl)-3-oxopropionate
CAS No.
22027-50-5
Chemical Name
Methyl 3-(4-methoxyphenyl)-3-oxopropionate
Synonyms
EINECS 244-732-0;CBI-BB ZERO/004684;MTHYL4-METHOXYBENZOYLACETATE;METHY 4-METHOXYBENZOYLACETATE;METHYL 4-METHOXYBENZOYLACETATE;Methyl 4-methoxy-β-oxobenzenepropanoate;Methyl-3-(p-methoxyphenyl)-3-oxopropionat;METHYL 3-(4-METHOXYPHENYL)-3-OXOPROPANOATE;Methyl 3-(4-methoxyphenyl)-3-oxopropionate;methyl 3-(p-methoxyphenyl)-3-oxopropionate
CBNumber
CB2666336
Molecular Formula
C11H12O4
Formula Weight
208.21
MOL File
22027-50-5.mol
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Methyl 3-(4-methoxyphenyl)-3-oxopropionate Property

Melting point:
40-42°C
Boiling point:
135°C/0.27mm
Density 
1.147±0.06 g/cm3(Predicted)
storage temp. 
Store at room temperature
pka
10.31±0.25(Predicted)
Appearance
White to off-white Solid
CAS DataBase Reference
22027-50-5(CAS DataBase Reference)
EPA Substance Registry System
Methyl 4-methoxy-.beta.-oxobenzenepropionate (22027-50-5)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M338603
Product name
Methyl3-(4-Methoxyphenyl)-3-oxopropionate
Packaging
100mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
126241
Product name
Methyl3-(4-methoxyphenyl)-3-oxo-propionate
Purity
>95%
Packaging
1g
Price
$18
Updated
2021/12/16
Matrix Scientific
Product number
126241
Product name
Methyl3-(4-methoxyphenyl)-3-oxo-propionate
Purity
>95%
Packaging
5g
Price
$54
Updated
2021/12/16
Matrix Scientific
Product number
126241
Product name
Methyl3-(4-methoxyphenyl)-3-oxo-propionate
Purity
>95%
Packaging
10g
Price
$100
Updated
2021/12/16
AK Scientific
Product number
B823
Product name
3-(4-Methoxyphenyl)-3-oxo-propionicacidmethylester
Packaging
100g
Price
$131
Updated
2021/12/16
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Methyl 3-(4-methoxyphenyl)-3-oxopropionate Chemical Properties,Usage,Production

Chemical Properties

Pale yellow solid

Synthesis

616-38-6

100-06-1

22027-50-5

Step 1. A solution of p-methoxyacetophenone (30 g, 200 mmol, 1.00 eq.) was added to a 500-mL three-necked round-bottom flask. Sodium hydride (13.6 g, 340 mmol, 1.70 equiv, 60% dispersed in mineral oil) was added in batches. The reaction was stirred at 50 °C for 10 minutes. The reaction mixture was slowly poured into 400 mL of ice water and the resulting solution was washed with ether (50 mL x 2) and subsequently acidified with acetic acid. The aqueous phase was extracted with ethyl acetate (200 mL x 3) and the organic phases were combined. The organic phase was dried sequentially with saturated sodium bicarbonate solution and sodium sulfate. The organic phase was concentrated under reduced pressure to give 37 g (87% yield) of methyl 3-(4-methoxyphenyl)-3-oxopropionate as a yellow oil.

References

[1] Chemistry - A European Journal, 2017, vol. 23, # 41, p. 9716 - 9720
[2] Chemistry - A European Journal, 2018, vol. 24, # 32, p. 8092 - 8097
[3] Molecules, 2015, vol. 20, # 9, p. 17275 - 17287
[4] Synthesis (Germany), 2016, vol. 48, # 5, p. 772 - 782
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 43, p. 13319 - 13323

Methyl 3-(4-methoxyphenyl)-3-oxopropionate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl 3-(4-methoxyphenyl)-3-oxopropionate manufacturers

Career Henan Chemical Co
Product
Methyl 3-(4-methoxyphenyl)-3-oxopropionate 22027-50-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-31

22027-50-5, Methyl 3-(4-methoxyphenyl)-3-oxopropionateRelated Search:

p-Anisidine Methyl 3-methoxypropionate Methyl acetate Kresoxim-methyl Triphenylphosphine oxide (Trifluoromethoxy)benzene Anisole Methyl propionate METHYL 3,3-DIMETHOXYPROPIONATE Methyl acrylate Methylparaben Bensulfuron methyl 4-Methoxyphenylacetone METSULFURON METHYL Thiophanate-methyl Methyl ETHYL 4-METHOXYBENZOYLACETATE Methyl bromide

  • 4-methoxy-beta-oxo-benzenepropanoicacimethylester
  • METHYL 4-METHOXYBENZOYLACETATE
  • CBI-BB ZERO/004684
  • 3-(4-METHOXYPHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER
  • methyl 3-(p-methoxyphenyl)-3-oxopropionate
  • EINECS 244-732-0
  • Methyl-3-(p-methoxyphenyl)-3-oxopropionat
  • METHYL 3-(4-METHOXYPHENYL)-3-OXOPROPANOATE
  • 3-(4-Methoxyphenyl)-3-oxopropanoic acid methyl ester
  • Methyl 3-(4-methoxyphenyl)-3-oxopropionate
  • MTHYL4-METHOXYBENZOYLACETATE
  • METHY 4-METHOXYBENZOYLACETATE
  • 3-Oxo-3-(4-methoxyphenyl)propanoic acid methyl ester
  • 3-Oxo-3-(4-methoxyphenyl)propionic acid methyl ester
  • 4-Methoxy-β-oxobenzenepropanoic acid methyl ester
  • β-Oxo-4-methoxybenzenepropanoic acid methyl ester
  • β-Oxo-4-methoxybenzenepropionic acid methyl ester
  • Benzenepropanoic acid, 4-methoxy-β-oxo-, methyl ester
  • 3-(4-Methoxyphenyl)-2-Methyl-3-oxopropanoate
  • Methyl 3-oxo-3-(4-Methoxyphenyl)propionate
  • Methyl 4-methoxy-β-oxobenzenepropanoate
  • 3-(4-Methoxyphenyl)-3-Oxopropanoic Acid Methyl Ester (Bke)
  • 22027-50-5