Methyl 3-(4-methoxyphenyl)-3-oxopropionate
- Product Name
- Methyl 3-(4-methoxyphenyl)-3-oxopropionate
- CAS No.
- 22027-50-5
- Chemical Name
- Methyl 3-(4-methoxyphenyl)-3-oxopropionate
- Synonyms
- EINECS 244-732-0;CBI-BB ZERO/004684;MTHYL4-METHOXYBENZOYLACETATE;METHY 4-METHOXYBENZOYLACETATE;METHYL 4-METHOXYBENZOYLACETATE;Methyl 4-methoxy-β-oxobenzenepropanoate;Methyl-3-(p-methoxyphenyl)-3-oxopropionat;METHYL 3-(4-METHOXYPHENYL)-3-OXOPROPANOATE;Methyl 3-(4-methoxyphenyl)-3-oxopropionate;methyl 3-(p-methoxyphenyl)-3-oxopropionate
- CBNumber
- CB2666336
- Molecular Formula
- C11H12O4
- Formula Weight
- 208.21
- MOL File
- 22027-50-5.mol
Methyl 3-(4-methoxyphenyl)-3-oxopropionate Property
- Melting point:
- 40-42°C
- Boiling point:
- 135°C/0.27mm
- Density
- 1.147±0.06 g/cm3(Predicted)
- storage temp.
- Store at room temperature
- pka
- 10.31±0.25(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 22027-50-5(CAS DataBase Reference)
- EPA Substance Registry System
- Methyl 4-methoxy-.beta.-oxobenzenepropionate (22027-50-5)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M338603
- Product name
- Methyl3-(4-Methoxyphenyl)-3-oxopropionate
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 126241
- Product name
- Methyl3-(4-methoxyphenyl)-3-oxo-propionate
- Purity
- >95%
- Packaging
- 1g
- Price
- $18
- Updated
- 2021/12/16
- Product number
- 126241
- Product name
- Methyl3-(4-methoxyphenyl)-3-oxo-propionate
- Purity
- >95%
- Packaging
- 5g
- Price
- $54
- Updated
- 2021/12/16
- Product number
- 126241
- Product name
- Methyl3-(4-methoxyphenyl)-3-oxo-propionate
- Purity
- >95%
- Packaging
- 10g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- B823
- Product name
- 3-(4-Methoxyphenyl)-3-oxo-propionicacidmethylester
- Packaging
- 100g
- Price
- $131
- Updated
- 2021/12/16
Methyl 3-(4-methoxyphenyl)-3-oxopropionate Chemical Properties,Usage,Production
Chemical Properties
Pale yellow solid
Synthesis
616-38-6
100-06-1
22027-50-5
Step 1. A solution of p-methoxyacetophenone (30 g, 200 mmol, 1.00 eq.) was added to a 500-mL three-necked round-bottom flask. Sodium hydride (13.6 g, 340 mmol, 1.70 equiv, 60% dispersed in mineral oil) was added in batches. The reaction was stirred at 50 °C for 10 minutes. The reaction mixture was slowly poured into 400 mL of ice water and the resulting solution was washed with ether (50 mL x 2) and subsequently acidified with acetic acid. The aqueous phase was extracted with ethyl acetate (200 mL x 3) and the organic phases were combined. The organic phase was dried sequentially with saturated sodium bicarbonate solution and sodium sulfate. The organic phase was concentrated under reduced pressure to give 37 g (87% yield) of methyl 3-(4-methoxyphenyl)-3-oxopropionate as a yellow oil.
References
[1] Chemistry - A European Journal, 2017, vol. 23, # 41, p. 9716 - 9720
[2] Chemistry - A European Journal, 2018, vol. 24, # 32, p. 8092 - 8097
[3] Molecules, 2015, vol. 20, # 9, p. 17275 - 17287
[4] Synthesis (Germany), 2016, vol. 48, # 5, p. 772 - 782
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 43, p. 13319 - 13323
Methyl 3-(4-methoxyphenyl)-3-oxopropionate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 3-(4-methoxyphenyl)-3-oxopropionate Suppliers
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- contact@chemcollect.de
- Country
- Germany
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View Lastest Price from Methyl 3-(4-methoxyphenyl)-3-oxopropionate manufacturers
- Product
- Methyl 3-(4-methoxyphenyl)-3-oxopropionate 22027-50-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-31