ChemicalBook > CAS DataBase List > LAMININ

LAMININ

Product Name
LAMININ
CAS No.
114956-81-9
Chemical Name
LAMININ
Synonyms
LAMININ;laminin, LN;LN, Human laminin;LAMININ, HUMAN PLACENTA;laminin from human placenta;Laminin from human fibroblasts ;cell culture derived, liquid, sterile-filtered;LAMININ FROM HUMAN PLACENTA CELL*CULTURE TESTED;laminin from engelbreth-holm-swarm murine sarcoma basement membrane;LAMININ FROM BASEMENT MEMBRANE OF ENGELBRETH HOLM-SWARM TRANSPLANTABLE MOUSE TUMOR
CBNumber
CB2711739
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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LAMININ Property

storage temp. 
-20°C
form 
liquid
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Safety

Hazard Codes 
B,Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L6274
Product name
Laminin from human placenta
Purity
liquid, BioReagent, suitable for cell culture
Packaging
0.5mg
Price
$653
Updated
2024/03/01
Sigma-Aldrich
Product number
L4544
Product name
Laminin from human fibroblasts
Purity
cell culture derived, liquid, sterile-filtered
Packaging
100μL
Price
$313
Updated
2024/03/01
Sigma-Aldrich
Product number
L2020
Product name
Laminin from Engelbreth-Holm-Swarm murine sarcoma basement membrane
Purity
1-2 mg/mL in Tris-buffered saline, 0.2 μm filtered, BioReagent, suitable for cell culture
Packaging
1mg
Price
$230
Updated
2024/03/01
Sigma-Aldrich
Product number
11243217001
Product name
Laminin
Purity
from mouse Engelbreth-Holm-Swarm (EHS) sarcoma
Packaging
1mg
Price
$392
Updated
2024/03/01
Usbiological
Product number
L1225-25
Product name
Laminin
Packaging
100ug
Price
$661
Updated
2021/12/16
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LAMININ Chemical Properties,Usage,Production

Uses

Laminin from human fibroblasts has been used:

  • in coating six-well plates for wound healing assay
  • as a substrate in cell adhesion and spreading assay
  • for differentiation of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) toward dopaminergic neurons
  • in corneal endothelial cell wound healing (migration) assay and corneal endothelial cell barrier assay

Laminin from human fibroblasts is recommended for use as a cell culture substratum at 1-2 μg/cm2. The optimal concentration does depend on cell type as well as the application or research objectives.

Uses

Laminin has been demonstrated to promote the attachment and growth of a variety of cells; used for the coating of culture dishes. It has been used for cell adhesion assay. It is recommended for use as a cell culture substratum at 1-2μg/cm2. The optimal concentration does depend on cell type as well as the application or research objectives.

General Description

Laminin is purified as laminin-nidogen complex from mouse Engelbreth-Holm-Swarm (EHS) sarcoma. Laminin is a heterotrimer made from α, β and γ chain subunits. It is a glycoprotein which is required for the structural scaffolding of basement membranes. Laminin supports growth and differentiation of many cell types including epithelial, endothelial, neural, muscle and liver cells.

Biological activity: Tested for the promotion of adherence of HT-1080 cells.
Species specificity: Active on most mammalian cells.

Biochem/physiol Actions

Laminin proteins are integral components of structural scaffolding in animal tissues. They associate with type IV collagen via entactin and perlecan and bind to cell membranes through integrin receptors, dystroglycan glycoprotein complexes and Lutheran blood group glycoproteins. Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth fragment.

LAMININ Preparation Products And Raw materials

Raw materials

Preparation Products

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114956-81-9, LAMININRelated Search:

DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) Cupric acetylacetonate PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Benzyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Tosylmethyl isocyanide METHYL ISOCYANOACETATE Aluminum acetylacetonate COBALT(II) ACETYLACETONATE 2,4-PENTANEDIONE, SILVER DERIVATIVE N-BUTYLISOCYANIDE Ethyl isocyanoacetate Ferric acetylacetonate LAMININ B1 CHAIN FRAGMENT (925-933),LAMININ FRAGMENT 925-933,LAMININ NONAPEPTIDE

  • LAMININ FROM HUMAN PLACENTA CELL*CULTURE TESTED
  • LAMININ
  • LAMININ, HUMAN PLACENTA
  • LAMININ FROM BASEMENT MEMBRANE OF ENGELBRETH HOLM-SWARM TRANSPLANTABLE MOUSE TUMOR
  • laminin from engelbreth-holm-swarm murine sarcoma basement membrane
  • laminin from human placenta
  • Laminin from human fibroblasts
  • Laminin from Engelbreth-Holm-Swarm murine sarcoma basement membrane 1-2 mg/mL in Tris buffered NaCl, 0.2 mum filtered, BioReagent, suitable for cell culture
  • LN, Human laminin
  • laminin, LN
  • cell culture derived, liquid, sterile-filtered
  • 114956-81-9
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Extracellular Matrix
  • Extracellular Matrix Peptides and Proteins
  • Cytoskeleton and Extracellular Matrix