2-Iodopyridine
- Product Name
- 2-Iodopyridine
- CAS No.
- 5029-67-4
- Chemical Name
- 2-Iodopyridine
- Synonyms
- JACS-5029-67-4;2-lodopyridine;2-IODOPYRIDINE;2-Pyridyl iodide;Pyridine, 2-iodo-;2-Iodine Pyridine;2-Iodopyridine 98%;2-Iodopyridine 2-IODOPYRIDINE, 95+%;2-Iodopyridine≥ 98% (GC)
- CBNumber
- CB2754297
- Molecular Formula
- C5H4IN
- Formula Weight
- 205
- MOL File
- 5029-67-4.mol
2-Iodopyridine Property
- Melting point:
- 118-120℃
- Boiling point:
- 52 °C (lit.)
- Density
- 1.928 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.6320(lit.)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Solid
- pka
- pK1:1.82(＋1) (25°C)
- color
- Pale yellow
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Light Sensitive
- InChIKey
- CCZWSTFVHJPCEM-UHFFFAOYSA-N
- CAS DataBase Reference
- 5029-67-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 558761
- Product name
- 2-Iodopyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $134.8
- Updated
- 2024/03/01
- Product number
- 558761
- Product name
- 2-Iodopyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $76.9
- Updated
- 2023/06/20
- Product number
- I0533
- Product name
- 2-Iodopyridine (stabilized with Na2S2O3)
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $65
- Updated
- 2024/03/01
- Product number
- I0533
- Product name
- 2-Iodopyridine (stabilized with Na2S2O3)
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $259
- Updated
- 2024/03/01
- Product number
- H63062
- Product name
- 2-Iodopyridine, 95%
- Packaging
- 5g
- Price
- $76.1
- Updated
- 2024/03/01
2-Iodopyridine Chemical Properties,Usage,Production
Chemical Properties
Light yellow liquid
Uses
2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Uses
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Reactions
2-Iodopyridine and 3-alkoxy-2-iodopyridines are oxidized by DMDO to give PyIO2 , which serve as oxidants for alcohols and sulfides.
In palladium-catalyzed aminocarbonylation of 2-iodopyridine, 3-iodopyridine and iodopyrazine were coupled with CO and various primary and secondary amines. The biologically relevant N-substituted nicotinamides and 3-pyridyl-glyoxylamides were obtained from 3-iodopyridine as a result of simple and double carbon monoxide insertions, respectively. The chemoselectivity towards the ketoamide can be increased by the elevation of CO pressure. On the other hand, N-alkyl and N-aryl-carboxamides were obtained exclusively from CO pressure of 1 to 90 bar by using 2-iodopyridine and iodopyrazine.
Pd-catalyzed aminocarbonylation of 2-iodopyridine and 3-iodopyridine with primary and secondary amines.
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 6757, 1990 DOI: 10.1016/S0040-4039(00)97163-6
General Description
2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Iodopyridine Suppliers
- Tel
- --
- Fax
- --
- him@interchim.com
- Country
- France
- ProdList
- 2725
- Advantage
- 58
View Lastest Price from 2-Iodopyridine manufacturers
- Product
- 2-Iodopyridine 5029-67-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-12
- Product
- 2-Iodopyridine 5029-67-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-01
- Product
- 2-Iodopyridine 5029-67-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10