ChemicalBook > CAS DataBase List > Propacetamol

Propacetamol

Product Name
Propacetamol
CAS No.
66532-85-2
Chemical Name
Propacetamol
Synonyms
Propacetamo;Pro-Dafalgan;PROPACETAMOL;Propacatemol;Propacetamol USP/EP/BP;4-Acetamidophenyl N,N-diethylglycinate;4-acetamidophenyl N,N-diethylaminoacetate;N,N-Diethylglycine 4-(acetylamino)phenyl ester;(Diethylamino)acetic acid 4-(acetylamino)phenyl;Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
CBNumber
CB2759429
Molecular Formula
C14H20N2O3
Formula Weight
264.32
MOL File
66532-85-2.mol
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Propacetamol Property

Melting point:
55-57 °C
Boiling point:
434.5±30.0 °C(Predicted)
Density 
1.132±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
H2O : 100 mg/mL (378.33 mM; Need ultrasonic)
pka
14.20±0.70(Predicted)
form 
Solid
color 
White to off-white
CAS DataBase Reference
66532-85-2(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015798
Product name
N,N-DIETHYLGLYCINE-4-(ACETYLAMINO)PHENYL ESTER
Purity
95.00%
Packaging
1G
Price
$939.89
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
100mg
Price
$35
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
1g
Price
$95
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
10g
Price
$475
Updated
2021/12/16
AHH
Product number
MT-58176
Product name
Propacetamol
Purity
98%
Packaging
5g
Price
$910
Updated
2021/12/16
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Propacetamol Chemical Properties,Usage,Production

Description

Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.

Uses

Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.

Definition

ChEBI: Propacetamol is an alpha-amino acid ester.

Contact allergens

Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).

Mechanism of action

It is a soluble glycine prodrug derivative of paracetamol. It is used as hydrochloride, for intramuscular or intravenous application and is rapidly metabolized to free paracetamol .

Propacetamol Preparation Products And Raw materials

Raw materials

Preparation Products

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Propacetamol Suppliers

TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
Advantage
52
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Hubei widely chemical technology Co., Ltd.
Tel
027-83991130 18627774460
Fax
027-83991130
Email
1718093273@QQ.COM
Country
China
ProdList
1880
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9578
Advantage
60
XinYao(Shenzhen) Biological Technology Co., Ltd.
Tel
0755-89880280
Fax
0755-89880280
Email
3004662104@qq.com
Country
China
ProdList
1829
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
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View Lastest Price from Propacetamol manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Propacetamol 66532-85-2
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2024-08-16
Dideu Industries Group Limited
Product
Propacetamol 66532-85-2
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-15

66532-85-2, PropacetamolRelated Search:


  • PROPACETAMOL
  • 4-Acetamidophenyl diethylaminoacetate hydrochloride
  • Pro-Dafalgan
  • N,N-Diethylglycine 4-(acetylamino)phenyl ester
  • (Diethylamino)acetic acid 4-(acetylamino)phenyl
  • 4-Acetamidophenyl N,N-diethylglycinate
  • 4-acetamidophenyl N,N-diethylaminoacetate
  • Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
  • Propacetamol USP/EP/BP
  • Propacatemol
  • Propacetamo
  • 66532-85-2
  • 66532-86-2