ChemicalBook > CAS DataBase List > Propacetamol
Propacetamol
- Product Name
- Propacetamol
- CAS No.
- 66532-85-2
- Chemical Name
- Propacetamol
- Synonyms
- Propacetamo;Pro-Dafalgan;PROPACETAMOL;Propacatemol;Propacetamol USP/EP/BP;4-Acetamidophenyl N,N-diethylglycinate;4-acetamidophenyl N,N-diethylaminoacetate;N，N-Diethylglycine 4-(acetylamino)phenyl ester;(Diethylamino)acetic acid 4-(acetylamino)phenyl;Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
- CBNumber
- CB2759429
- Molecular Formula
- C14H20N2O3
- Formula Weight
- 264.32
- MOL File
- 66532-85-2.mol
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Propacetamol Property
- Melting point:
- 55-57 °C
- Boiling point:
- 434.5±30.0 °C(Predicted)
- Density
- 1.132±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- H2O : 100 mg/mL (378.33 mM; Need ultrasonic)
- pka
- 14.20±0.70(Predicted)
- form
- Solid
- color
- White to off-white
- CAS DataBase Reference
- 66532-85-2(CAS DataBase Reference)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0015798
- Product name
- N,N-DIETHYLGLYCINE-4-(ACETYLAMINO)PHENYL ESTER
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $939.89
- Updated
- 2021/12/16
AvaChem
- Product number
- 3086B
- Product name
- Propacetamol
- Packaging
- 100mg
- Price
- $35
- Updated
- 2021/12/16
AvaChem
- Product number
- 3086B
- Product name
- Propacetamol
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
AvaChem
- Product number
- 3086B
- Product name
- Propacetamol
- Packaging
- 10g
- Price
- $475
- Updated
- 2021/12/16
AHH
- Product number
- MT-58176
- Product name
- Propacetamol
- Purity
- 98%
- Packaging
- 5g
- Price
- $910
- Updated
- 2021/12/16
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Propacetamol Chemical Properties,Usage,Production
Description
Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.
Uses
Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.
Definition
ChEBI: Propacetamol is an alpha-amino acid ester.
Contact allergens
Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).
Mechanism of action
It is a soluble glycine prodrug derivative of paracetamol. It is used as hydrochloride, for intramuscular or intravenous application and is rapidly metabolized to free paracetamol .
Propacetamol Preparation Products And Raw materials
Raw materials
Phenyl ester
Chloroacetic acid
Potassium iodide
Potassium carbonate
Diethylamine
Chloroacetyl chloride
Aniline
Preparation Products
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View Lastest Price from Propacetamol manufacturers
Hebei Chuanghai Biotechnology Co,.LTD
- Product
- Propacetamol 66532-85-2
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.8%
- Supply Ability
- 100tons
- Release date
- 2024-08-16
Dideu Industries Group Limited
- Product
- Propacetamol 66532-85-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-15
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