ChemicalBook > CAS DataBase List > Propacetamol

Propacetamol

Product Name
Propacetamol
CAS No.
66532-85-2
Chemical Name
Propacetamol
Synonyms
Propacetamo;Pro-Dafalgan;PROPACETAMOL;Propacatemol;Propacetamol USP/EP/BP;4-Acetamidophenyl N,N-diethylglycinate;4-acetamidophenyl N,N-diethylaminoacetate;N,N-Diethylglycine 4-(acetylamino)phenyl ester;(Diethylamino)acetic acid 4-(acetylamino)phenyl;Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
CBNumber
CB2759429
Molecular Formula
C14H20N2O3
Formula Weight
264.32
MOL File
66532-85-2.mol
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Propacetamol Property

Melting point:
55-57 °C
Boiling point:
434.5±30.0 °C(Predicted)
Density 
1.132±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
H2O : 100 mg/mL (378.33 mM; Need ultrasonic)
pka
14.20±0.70(Predicted)
CAS DataBase Reference
66532-85-2(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015798
Product name
N,N-DIETHYLGLYCINE-4-(ACETYLAMINO)PHENYL ESTER
Purity
95.00%
Packaging
1G
Price
$939.89
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
100mg
Price
$35
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
1g
Price
$95
Updated
2021/12/16
AvaChem
Product number
3086B
Product name
Propacetamol
Packaging
10g
Price
$475
Updated
2021/12/16
AHH
Product number
MT-58176
Product name
Propacetamol
Purity
98%
Packaging
5g
Price
$910
Updated
2021/12/16
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Propacetamol Chemical Properties,Usage,Production

Description

Propacetamol is the prodrug of paracetamol (acetaminophen), used for intravenous administration. It results from eombination of paracetamol and diethylglycine. Causes contact dermatitis and airborne dermatitis in nurses. Allergenic properties are due to the N,N' -diethylglycine moiety, and not to the paracetamol moiety.

Uses

Propacetamol hydrochloride is a water-soluble prodrug for intravenous administration resulting in the liberation of paracetamol.

Definition

ChEBI: Propacetamol is an alpha-amino acid ester.

Contact allergens

Propacetamol is a prodrug of paracetamol (acetaminophen) used for intravenous administration. It results from the combination of paracetamol and diethylglycine. It caused contact (hand and airborne) dermatitis in nurses and acute systemic dermatitis (pompholyx and nummular dermatitis, generalized eczema, urticaria-like eruption) in nurses who had became sick and received intravenous propacetamol. Allergenic properties are due to the N,N-diethylglycine moiety, and not to the paracetamol moiety. Propacetamol is now substituted by a solution of paracetamol in mannitol (Perfalgan?).

Mechanism of action

It is a soluble glycine prodrug derivative of paracetamol. It is used as hydrochloride, for intramuscular or intravenous application and is rapidly metabolized to free paracetamol .

Propacetamol Preparation Products And Raw materials

Raw materials

Preparation Products

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Propacetamol Suppliers

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View Lastest Price from Propacetamol manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Propacetamol 66532-85-2
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29
Hebei Guanlang Biotechnology Co,.LTD
Product
Propacetamol 66532-85-2
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2022-01-21
Dideu Industries Group Limited
Product
Propacetamol 66532-85-2
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-15

66532-85-2, PropacetamolRelated Search:


  • PROPACETAMOL
  • 4-Acetamidophenyl diethylaminoacetate hydrochloride
  • Pro-Dafalgan
  • N,N-Diethylglycine 4-(acetylamino)phenyl ester
  • (Diethylamino)acetic acid 4-(acetylamino)phenyl
  • 4-Acetamidophenyl N,N-diethylglycinate
  • 4-acetamidophenyl N,N-diethylaminoacetate
  • Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester
  • Propacetamol USP/EP/BP
  • Propacatemol
  • Propacetamo
  • 66532-85-2
  • 66532-86-2