ChemicalBook > CAS DataBase List > Temocapril hydrochloride

Temocapril hydrochloride

Product Name
Temocapril hydrochloride
CAS No.
110221-44-8
Chemical Name
Temocapril hydrochloride
Synonyms
CS-622;Acecol;CS-622 HCl;TemocarpileHCL;Temocapril Hcl;Carbovir Impurity 4;Temocarpilhydrochloride;TEMOCAPRIL HYDROCHLORIDE;CS-622 HCl|Temocapril HCl;Temocapril hydrochloride, >=99%
CBNumber
CB2841030
Molecular Formula
C23H28N2O5S2.ClH
Formula Weight
513.076
MOL File
110221-44-8.mol
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Temocapril hydrochloride Property

Melting point:
196-2000C (dec)
alpha 
25D +47.7° (c = 1 in DMF)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
110221-44-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
Toxicity
LD50 in mice, rats, dogs (mg/kg): >5000, >5000, >800 orally (Koike)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18241
Product name
Temocapril (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
18241
Product name
Temocapril (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
18241
Product name
Temocapril (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
18241
Product name
Temocapril (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$214
Updated
2024/03/01
TRC
Product number
T017301
Product name
TemocaprilHydrochloride
Packaging
5mg
Price
$60
Updated
2021/12/16
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Temocapril hydrochloride Chemical Properties,Usage,Production

Description

Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of hypertension. Temocapril is three times more potent than enalapril by oral administration, and has a long duration of action. It is characterized by a rapid onset of action resulting from a fast conversion of temocapril to the active metabolite diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys, temocapril is excreted predominantly through the biliary route indicating that temocapril is especially useful for treating hypertensive patients with renal dysfunction. The potential usefulness of temocapril in the treatment of congestive heart failure has been reported.

Chemical Properties

White To Off-White Solid

Originator

Sankyo (Japan)

Uses

Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.

Uses

angiotensin-converting enzyme inhibitor (ACE-I)

Definition

ChEBI: Temocapril hydrochloride is a dipeptide.

brand name

Acecol

Temocapril hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Temocapril hydrochloride Suppliers

Canada 1 China 152 Germany 1 India 3 South Korea 1 United Kingdom 4 United States 20 Global 182
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View Lastest Price from Temocapril hydrochloride manufacturers

Hebei Duling International Trade Co. LTD
Product
Temocapril hydrochloride 110221-44-8
Price
US $25.00-18.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-01-06
Zhuozhou Wenxi import and Export Co., Ltd
Product
Temocapril hydrochloride 110221-44-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Temocapril hydrochloride 110221-44-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

110221-44-8, Temocapril hydrochlorideRelated Search:

Cephalothin sodium D-Glucosamine hydrochloride Methoxyammonium chloride Triethylamine hydrochloride Glycine 6-Aminocaproic acid 2-Aminophenol Tetrahydrothiophene Tris(hydroxymethyl)aminomethane Thifensulfuron Cetirizine dihydrochloride Topotecan hydrochloride Pyridine hydrochloride 1,1'-Carbonyldiimidazole Temocaprilat ALTRENOGEST 2-[(2S)-6-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid L-Homophenylalanine ethyl ester hydrochloride

  • TEMOCAPRIL HYDROCHLORIDE
  • Temocapril HCl and intermediates
  • Acecol
  • CS-622
  • 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, (2S,6R)- (9CI)
  • 1,4-Thiazepine-4(5H)-acetic acid, 6-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, [2S-[2a,6b(R*)]]-
  • Temocapril Hcl
  • TemocarpileHCL
  • Temocarpilhydrochloride
  • (2S,6R)-6-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid Hydrochloride
  • (+)-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetic acid hydrochloride
  • (2S,6R)-6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic acid,hydrochloride (1:1)
  • CS-622 HCl
  • Temocapril hydrochloride, >=99%
  • 2-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)-2,5,6,7-tetrahydro-1,4-thiazepine-4(3H)-yl]acetic acid·hydrochloride
  • 1,4-Thiazepine-4(5H)-aceticacid,6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-,hydrochloride (1:1), (2S,6R)-
  • 2-[6-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid hydrochloride
  • Temocapril hydrochloride USP/EP/BP
  • TIANFU-CHEM - Temocapril hydrochloride
  • 2-((2S,6R)-6-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride
  • Carbovir Impurity 4
  • CS-622 HCl|Temocapril HCl
  • 110221-44-8
  • 10221-44-8
  • 110221-48-8
  • C23H28N2O5S2HCl
  • C23H28N2O5S2xHCl
  • C23H29ClN2O5S2
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Inhibitors