2-Amino-5-trifluoromethylbenzonitrile

Product Name: 2-Amino-5-trifluoromethylbenzonitrile
CAS No.: 6526-08-5
Chemical Name: 2-Amino-5-trifluoromethylbenzonitrile
Synonyms: 0/5/26;4-Amino-3-cyanobenzotrifluoride;2-Amino-5-trifluoromethylbenzonitrile;Benzonitrile, 2-aMino-5-(trifluoroMethyl)-;4-Amino-3-cyanobenzotrifluoride, 2-Cyano-4-(trifluoromethyl)aniline
CBNumber: CB2971740
Molecular Formula: C8H5F3N2
Formula Weight: 186.13
MOL File: 6526-08-5.mol

More

Less

2-Amino-5-trifluoromethylbenzonitrile Property

Melting point:: 72-74 °C(Solv: benzene (71-43-2))
Boiling point:: 95-115 C
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -0.02±0.10(Predicted)
form: crystalline powder
color: Faint lemon

More

Less

Safety

Hazard Codes: T
HS Code: 2926907090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Matrix Scientific

Product number: 073957
Product name: 3-Cyano-4-aminobenzotrifluoride
Purity: 95+%
Packaging: 1g
Price: $27
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3837-3-07
Product name: 4-Amino-3-cyanobenzotrifluoride
Purity: 98%
Packaging: 1g
Price: $35
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA64112
Product name: 2-Amino-5-(trifluoromethyl)benzonitrile
Packaging: 10g
Price: $80
Updated: 2021/12/16

Matrix Scientific

Product number: 073957
Product name: 3-Cyano-4-aminobenzotrifluoride
Purity: 95+%
Packaging: 5g
Price: $88
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3837-3-07
Product name: 4-Amino-3-cyanobenzotrifluoride
Purity: 98%
Packaging: 5G
Price: $90
Updated: 2021/12/16

More

Less

2-Amino-5-trifluoromethylbenzonitrile Chemical Properties,Usage,Production

Synthesis

544-92-3

57946-63-1

6526-08-5

A reaction was carried out with cuprous cyanide (2.24 g, 25.00 mmol) and 2-bromo-4-(trifluoromethyl)aniline (5.0 g, 20.83 mmol) in N-methyl-2-pyrrolidone (20 mL) heated at 195 °C for 4 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (100 mL) and washed twice with 28% aqueous ammonium hydroxide solution, twice with saturated aqueous sodium chloride solution (brine), and twice with water, in that order. The organic layer was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The resulting residue was purified by fast chromatography using hexane as the starting eluent and gradually increasing the proportion of ethyl acetate to a gradient elution of 30% hexane-70% ethyl acetate, resulting in 2-amino-5-trifluoromethylbenzonitrile (1.821 g, 9.78 mmol, 47% yield) as a green amorphous solid. Mass spectrum (m/e): 187 (M + 1).

References

[1] Patent: WO2004/14895, 2004, A1. Location in patent: Page 68

2-Amino-5-trifluoromethylbenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Amino-5-trifluoromethylbenzonitrile Suppliers

China 118 India 2 Italy 1 United Kingdom 5 United States 9 Global 135

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

6526-08-5, 2-Amino-5-trifluoromethylbenzonitrileRelated Search:

Benzotrifluoride ALTRENOGEST 2-(Trifluoromethyl)benzaldehyde 1,4-Bis(trifluoromethyl)-benzene 3-(Trifluoromethyl)benzoic acid Glycine 4'-(Trifluoromethyl)acetophenone 2,3-DIAMINOTOLUENE Diaminomaleonitrile 3-(Trifluoromethyl)benzaldehyde 3-Fluorobenzotrifluoride p-Tolunitrile 2-Methylbenzotrifluoride Phenylmethylsulfonyl fluoride Tris(hydroxymethyl)aminomethane TRITON 3-(Trifluoromethyl)benzonitrile 2-Amino-5-Methyl-Benzonitrile

2-Amino-5-trifluoromethylbenzonitrile

4-Amino-3-cyanobenzotrifluoride

Benzonitrile, 2-aMino-5-(trifluoroMethyl)-

4-Amino-3-cyanobenzotrifluoride, 2-Cyano-4-(trifluoromethyl)aniline

0/5/26

6526-08-5

6526-8-5

Fluorine series

Benzotrifluoride Series