ChemicalBook > CAS DataBase List > Rink Amide Linker

Rink Amide Linker

Product Name: Rink Amide Linker
CAS No.: 145069-56-3
Chemical Name: Rink Amide Linker
Synonyms: FMoc-Linker;RINK AMIDE LINKER;FMOC-RINK LINKER;DK7874;RAMAGE;Fmoc-Liner;KNORR LINKER;Rink Amide Linke;Rink AMind Linker;FMOC-AMIDE-LINKER
CBNumber: CB3104341
Molecular Formula: C32H29NO7
Formula Weight: 539.58
MOL File: 145069-56-3.mol

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Rink Amide Linker Property

Melting point:: ~180 °C (dec.)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
BRN: 5841553
InChIKey: UPMGJEMWPQOACJ-UHFFFAOYSA-N
SMILES: C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1
CAS DataBase Reference: 145069-56-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 22-24/25-37/39-26
WGK Germany: 3
HS Code: 29242995

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 38784
Product name: 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid
Purity: ≥99.0% (HPLC)
Packaging: 5g
Price: $50.8
Updated: 2023/01/07

TRC

Product number: R590710
Product name: RinkAmideLinker
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: CS-W011472
Product name: 2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)(2,4-dimethoxyphenyl)methyl)phenoxy)aceticacid
Packaging: 25g
Price: $108
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIN0000011
Product name: RINK AMIDE LINKER
Purity: 95.00%
Packaging: 1G
Price: $115.5
Updated: 2021/12/16

ApexBio Technology

Product number: A7042
Product name: RinkAmideLinker
Packaging: 25g
Price: $148
Updated: 2021/12/16

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Rink Amide Linker Chemical Properties,Usage,Production

Uses

Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug.

Application

Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1].

Origin

Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker.

reaction suitability

reagent type: cross-linking reagent

References

[1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.

Rink Amide Linker Preparation Products And Raw materials

Raw materials

Preparation Products

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Rink Amide Linker Suppliers

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View Lastest Price from Rink Amide Linker manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc -Rink Linker 145069-56-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-27

Hebei Dangtong Import and export Co LTD

Product: Rink Amide Linker 145069-56-3
Price: US $100.00-80.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200Tons
Release date: 2023-11-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid 145069-56-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

145069-56-3, Rink Amide LinkerRelated Search:

Fmoc-Phe-OH Fmoc-Asp(OtBu)-OH Fmoc-Lys(Boc)-OH Dimethyldimethoxysilane Fomesafen RINK AMIDE RESIN 4-Dimethylaminopyridine 4-Dimethylaminobenzaldehyde Phenyltriethoxysilane Glycine 9-Fluorenylmethyl chloroformate 6-Aminocaproic acid 3,4'-DIAMINODIPHENYLMETHANE L-Fmoc-Aspartic acid alpha-tert-butyl ester Dimethoxymethane Fmoc-OSu 2-Dimethylaminoethanol FMOC-RINK AMIDE-LINKER

Rink AMid Linker, (FoMc-AM, Knorr linker)

Rink AMind Linker

Rink Amide Linke

FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE

4-[(2,4-DiMethoxyphenyl)(FMoc-aMino)Methyl]phenoxyacetic acid, 98+%

RINK AMIDE REAGENT

RINK AMIDE LINKER

N-FMOC-(2,4-DIMETHOXYPHENYL)AMINOMETHYL PHENOXY ACETIC ACID

P-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID

P-((R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID

P-((R,S)-ALPHA-[1-(9H-FLOUREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE

4-(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC-ACID

4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID

4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOL

4-[(R,S)-ALPHA-1-(9H-FLUREN-9-YL)-METHOXY FORMAMIDO]-2,4-DIMETHOXYBENZYLPHENOXYACETIC ACID

4-[(R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID

4-(2',4'-DIMETHOXYPHENYL)-FMOC-AMINOMETHYL-PHENOXYACETIC ACID

4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID

FMOC-AMIDE-LINKER

FMOC-RINK LINKER

FMOC-RINK AMIDE-LINKER

FMOC RINK ACETIC ACID LINKER

FMOC-NH-SAL RESIN LINKER

KNORR LINKER

Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid 145069-56-3 C32h29no7

Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid

Fmoc-Liner

Fmoc-Linker(4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]-PhenoxyaceticAcid)

4-[(2,4-dimethoxyphenyl)(fmoc-amino)me] phenoxy acetic acid

4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID[RINK AMIDE LINKER]

4-[(2,4-DIMETHOXYPHENYL) (FMOC-AMINO) METHYL] PHENOXYACETIC ACID RINK AMIDE LINKER 98.5%

RINK AMIDE LINKER:KNORR LINKER:4-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID

Knorr-Linker, 4-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid

RINK AMIDE LINKER, 98.5% MIN.

4-[(R,S)--[1-(9H-Fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzylphenoxyacetic acid

4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido]-2

2-(4-((((9H-fluoren-9-yl)methoxy)carbonylamino)(2,4-dimethoxyphenyl)methyl)phenoxy)acetic acid

4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido]

FMoc-Linker

2-{4-[(2,4-diMethoxyphenyl)({[(9H-fluoren-9-ylMethoxy)carbonyl]aMino})Methyl]phenoxy}acetic acid

Fmoc-Knorr-Linker: Fmoc-Rink Amide Linker (2), 4′-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid

Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(FMOC amino)methyl)ph

2-[4-[(2,4-dimethoxyphenyl)-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]methyl]phenoxy]acetic acid

Rink Amide Linker, 99% min.

4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]PhenoxyaceticAci

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid USP/EP/BP

DK7874

Rink Amide Linker Resin (Knorr Linker) extrapure, 99%

RAMAGE

4-2,4-Dimethoxyphenylmethyl] phenoxyacetic acid

145069-56-3

145068-56-3

C32H28NO7

C32H29NO7

Bifunctional Crosslinkers

Linkers

Peptide Synthesis