ChemicalBook > CAS DataBase List > Trimethyl-pyrazine

Trimethyl-pyrazine

Product Name
Trimethyl-pyrazine
CAS No.
14667-55-1
Chemical Name
Trimethyl-pyrazine
Synonyms
Pyrazine, trimethyl-;2,3,5-TRIMETHYLPYRAZINE;TRIMETHYLPYRAZINE;2,3,5-TriMethylpyrazine 99%;FEMA 3244;FEMA NUMBER 3244;Compound Fr14500;trimethyl-pyrazin;2.3.5-Methyl pyrazine;TRIMETHYLPYRAZINE,2,3,5
CBNumber
CB3105641
Molecular Formula
C7H10N2
Formula Weight
122.17
MOL File
14667-55-1.mol
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Trimethyl-pyrazine Property

Melting point:
156 °C
Boiling point:
171-172 °C (lit.)
Density 
0.979 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.5040(lit.)
FEMA 
3244 | 2,3,5-TRIMETHYLPYRAZINE
Flash point:
130 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly)
pka
2.69±0.10(Predicted)
form 
Liquid
color 
Colorless to Light yellow to Light orange
Specific Gravity
0.979
Odor
roasted odor, reminiscent of coffee and cocoa
Odor Type
nutty
biological source
synthetic
JECFA Number
774
BRN 
2423
InChIKey
IAEGWXHKWJGQAZ-UHFFFAOYSA-N
LogP
1.10
CAS DataBase Reference
14667-55-1(CAS DataBase Reference)
NIST Chemistry Reference
Pyrazine, trimethyl-(14667-55-1)
EPA Substance Registry System
Trimethylpyrazine (14667-55-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
10-22-36/37/38
Safety Statements 
16-26-36/37/39
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
UQ3907000
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29339900
Toxicity
rat,LD50,oral,806mg/kg (806mg/kg),Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W324426
Product name
2,3,5-Trimethylpyrazine
Purity
natural, ≥95%, FG
Packaging
1 unit
Price
$58.42
Updated
2025/07/31
Sigma-Aldrich
Product number
W324426
Product name
2,3,5-Trimethylpyrazine
Purity
natural, ≥95%, FG
Packaging
1 unit
Price
$58.42
Updated
2025/07/31
Sigma-Aldrich
Product number
W324426
Product name
2,3,5-Trimethylpyrazine
Purity
natural, ≥95%, FG
Packaging
100g
Price
$465.5
Updated
2025/07/31
Sigma-Aldrich
Product number
W324426
Product name
2,3,5-Trimethylpyrazine
Purity
natural, ≥95%, FG
Packaging
1kg
Price
$4530
Updated
2025/07/31
Sigma-Aldrich
Product number
W324418
Product name
2,3,5-Trimethylpyrazine
Purity
≥99%, FCC, FG
Packaging
1 unit
Price
$56.3
Updated
2025/07/31
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Trimethyl-pyrazine Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Chemical Properties

2,3,5-Trimethylpyrazine has a baked potato or roasted nut aroma.

Occurrence

Reported present in bakery products, roasted barley, cocoa products, coffee, dairy products, meat, peanuts, filberts, pecans, popcorn, potato products, rum and whiskey, soy products, raw asparagus, baked potato, wheaten bread, crispbread, Swiss cheese, coffee, black tea, green tea, roasted barley, roasted filbert, heated beef, roasted peanut, soybean, raw beans, coriander seed, scallop, guava, kohlrabi, bell pepper, blue, Swiss and Gruyere cheese, boiled egg, fatty fish, beer, sherry, barley, peanut, oat products, coconut, beans, mushroom, trassi, almond, macadamia nut, sesame seed, coriander seed, rice, licorice, sweet corn, malt, peated malt, wort, krill, fermented shrimp, crab, okra, crayfish, clam, scallop and squid.

Uses

Trimethylpyrazine is a key aroma compound of dark chocolates differing in organoleptic properties.

Uses

2,3,5-Trimethylpyrazine can be used as a flavor ingredient in food industries.

Definition

ChEBI: Trimethylpyrazine is a member of the class of pyrazines that is pyrazine in which three hydrogens at positions 2, 3 and 5 have been replaced by methyl groups. It has a role as a plant metabolite, a flavouring agent, a bacterial metabolite, an animal metabolite and a pheromone.

Preparation

From 2,5-dimethylpyrazine by ring alkylation with MeLi; by condensing propylenediamine with 2,3-butanedione.

Aroma threshold values

Detection: 400 ppb to 9 ppm (9 ppm in water)

Taste threshold values

Taste characteristics at 80 ppm: raw, musty, nutty and potato.

General Description

2,3,5-Trimethylpyrazine is present in brown cheese.

Safety Profile

Moderately toxic by ingestion. Combustible liquid. When heated to decomposition emits toxic fumes of NOx.

Trimethyl-pyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Ethyl-3,5-dimethylpyrazine
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Trimethyl-pyrazine Suppliers

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View Lastest Price from Trimethyl-pyrazine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Trimethyl-pyrazine 14667-55-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
Trimethyl-pyrazine 14667-55-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-05
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Trimethyl-pyrazine 14667-55-1
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-11-18

14667-55-1, Trimethyl-pyrazineRelated Search:

Trimethoxypropylsilane Trimethylsilyl cyanide Trimethylsilyl trifluoromethanesulfonate Trimethylsilylacetylene Trimethoxysilane Trimethyl thiazole Trimethoxysilylpropanethiol Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate Trimethyl orthobenzoate 2-Acetyl-3,5-dimethylpyrazine 2,3-Diethyl-5-methylpyrazine 2,3-DICYANO-5-METHYLPYRAZINE Tetramethylpyrazine 3-Ethyl-2,5-diMethylpyrazine Trimethyl-pyrazine 3,5-dimethyl-2-propylpyrazine 2-CHLORO-3,5,6-TRIPHENYLPYRAZINE 2,3-DICYANO-5,6-DIPHENYLPYRAZINE

  • 2,3,5-TriMethylpyrazine 99%
  • 2,3,5-Trimethylpyrazine ,98%
  • 2,3,5-Trimethylpyrazine,99%
  • 2,3,5-Trimethyl-pyrazine >=99.0%
  • 2,3,5-Trimethyl prazine
  • 2.3.5-Methyl pyrazine
  • 2,3,5-Trimethylpyrazine Trimethyl-pyrazine
  • Natural 2,3,5-Trimethylpyrazine
  • Pyrazine,2,3,5-trimethyl-
  • TRIMETHYLPYRAZINE
  • TRIMETHYLPYRAZINE,2,3,5
  • FEMA 3244
  • FEMA NUMBER 3244
  • 2,3,6-TRIMETHYLPYRAZINE
  • 2,3,5-TRIMETHYLPYRAZINE
  • trimethyl-pyrazin
  • 2 3 5-TRIMETHYLPYRAZINE 99+% FCC
  • trimethyl-pyrazine,2,3,5-trimethylpyrazine
  • Pyrazine, trimethyl-
  • TRIMETHYLPYRAZINE,2,3,5-(SG)
  • 2,3,5-TRIMETHYL PYRAZINE FEMA NO.3244
  • 2,3,5-TRIMETHYL PYRAZINE, NATURAL
  • Trimethyl-pyrazine USP/EP/BP
  • 2-Methoxy-3-sec-butyl pyrazine 24168-70-5
  • 2,3,5-Trimethylpyrazine (AS)
  • Compound Fr14500
  • 2,3,5-Trimethylpyrazine in isooctane
  • 14667-55-1
  • 14666-55-1
  • Pyrazines
  • Mono- & Polyalkylpyrazines
  • Building Blocks
  • Heterocyclic Building Blocks
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Pyrazine compounds
  • Building Blocks
  • Heterocyclic Building Blocks
  • Alphabetical Listings
  • Flavors and Fragrances
  • Q-Z
  • Mono- & Polyalkylpyrazines
  • pyrazine Flavor
  • Heterocyclic Compounds
  • Pyrazines