ChemicalBook > CAS DataBase List > 3-BROMO-4-CHLOROANILINE

3-BROMO-4-CHLOROANILINE

Product Name
3-BROMO-4-CHLOROANILINE
CAS No.
823-54-1
Chemical Name
3-BROMO-4-CHLOROANILINE
Synonyms
3-BROMO-4-CHLOROANILINE;3-Bromo-4-chlorophenylamine;3-Bromo-4-chlorobenzenamine;3-Bromo-4-chloroaniline >BenzenaMine,3-broMo-4-chloro-
CBNumber
CB31091222
Molecular Formula
C6H5BrClN
Formula Weight
206.47
MOL File
823-54-1.mol
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3-BROMO-4-CHLOROANILINE Property

Melting point:
82°C
Boiling point:
290.6±20.0℃ (760 Torr)
Density 
1.722±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
129.5±21.8℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
powder to crystal
pka
2.89±0.10(Predicted)
color 
White to Brown
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Safety

Risk Statements 
20/21/22-33
Safety Statements 
36/37
RIDADR 
2811
HazardClass 
6.1
PackingGroup 
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS020727
Product name
3-Bromo-4-chloroaniline
Packaging
50MG
Price
$35.6
Updated
2024/03/01
TCI Chemical
Product number
B4160
Product name
3-Bromo-4-chloroaniline
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$78
Updated
2024/03/01
TRC
Product number
B821053
Product name
3-Bromo-4-chloroaniline
Packaging
500mg
Price
$75
Updated
2021/12/16
TRC
Product number
B821053
Product name
3-Bromo-4-chloroaniline
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139556
Product name
3-Bromo-4-chloroaniline
Packaging
10g
Price
$60
Updated
2021/12/16
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3-BROMO-4-CHLOROANILINE Chemical Properties,Usage,Production

Description

3-Bromo-4-chloroaniline can be used as an intermediate in pharmaceutical synthesis, such as the preparation of Vismodegib, the trade name is Erivedge, the chemical name is 2-chloro-N-(4-chloro-3 -(Pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, developed by Curis, Genentech and Evotec in cooperation, was approved by the U.S. Food and Drug Administration (FDA) on January 30, 2012 ) marketing approval as a small molecule targeted inhibitor of the Hedgehog pathway for the treatment of basal cell carcinoma.

Uses

3-Bromo-4-chloroaniline is an amine derivative and can be used as an organic reagent.

Synthesis

Dissolve p-chloronitrobenzene in sulfuric acid aqueous solution, slowly add bromine reagent (bromine or potassium bromate), and react to obtain 3-bromo-4-chloroaniline.

3-BROMO-4-CHLOROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-4-CHLOROANILINE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
21-31038972 15721252604
Fax
+86-21-51385350
Email
ammyzuo@harvest-chem.com
Country
China
ProdList
2511
Advantage
64
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View Lastest Price from 3-BROMO-4-CHLOROANILINE manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
3-Bromo-4-chloroaniline 823-54-1
Price
US $100.00-30.00/kg
Min. Order
1kg
Purity
99.93%
Supply Ability
1000kg per week
Release date
2024-04-25
Hebei Mojin Biotechnology Co., Ltd
Product
3-BROMO-4-CHLOROANILINE 823-54-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-04
Hebei Guanlang Biotechnology Co., Ltd.
Product
3-BROMO-4-CHLOROANILINE 823-54-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-23