ChemicalBook > CAS DataBase List > 3-BROMO-4-CHLOROANILINE

3-BROMO-4-CHLOROANILINE

Product Name
3-BROMO-4-CHLOROANILINE
CAS No.
823-54-1
Chemical Name
3-BROMO-4-CHLOROANILINE
Synonyms
3-BROMO-4-CHLOROANILINE;3-Bromo-4-chlorophenylamine;3-Bromo-4-chlorobenzenamine;3-Bromo-4-chloroaniline >BenzenaMine,3-broMo-4-chloro-
CBNumber
CB31091222
Molecular Formula
C6H5BrClN
Formula Weight
206.47
MOL File
823-54-1.mol
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3-BROMO-4-CHLOROANILINE Property

Melting point:
82°C
Boiling point:
290.6±20.0℃ (760 Torr)
Density 
1.722±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
129.5±21.8℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
powder to crystal
pka
2.89±0.10(Predicted)
color 
White to Brown
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Safety

Risk Statements 
20/21/22-33
Safety Statements 
36/37
RIDADR 
2811
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS020727
Product name
3-Bromo-4-chloroaniline
Packaging
50MG
Price
$35.6
Updated
2024/03/01
TCI Chemical
Product number
B4160
Product name
3-Bromo-4-chloroaniline
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$78
Updated
2024/03/01
TRC
Product number
B821053
Product name
3-Bromo-4-chloroaniline
Packaging
500mg
Price
$75
Updated
2021/12/16
TRC
Product number
B821053
Product name
3-Bromo-4-chloroaniline
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139556
Product name
3-Bromo-4-chloroaniline
Packaging
10g
Price
$60
Updated
2021/12/16
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3-BROMO-4-CHLOROANILINE Chemical Properties,Usage,Production

Description

3-Bromo-4-chloroaniline can be used as an intermediate in pharmaceutical synthesis, such as the preparation of Vismodegib, the trade name is Erivedge, the chemical name is 2-chloro-N-(4-chloro-3 -(Pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, developed by Curis, Genentech and Evotec in cooperation, was approved by the U.S. Food and Drug Administration (FDA) on January 30, 2012 ) marketing approval as a small molecule targeted inhibitor of the Hedgehog pathway for the treatment of basal cell carcinoma.

Uses

3-Bromo-4-chloroaniline is an amine derivative and can be used as an organic reagent.

Synthesis

Dissolve p-chloronitrobenzene in sulfuric acid aqueous solution, slowly add bromine reagent (bromine or potassium bromate), and react to obtain 3-bromo-4-chloroaniline.

3-BROMO-4-CHLOROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-4-CHLOROANILINE Suppliers

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View Lastest Price from 3-BROMO-4-CHLOROANILINE manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
3-BROMO-4-CHLOROANILINE 823-54-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-23
Hebei Mojin Biotechnology Co., Ltd
Product
3-BROMO-4-CHLOROANILINE 823-54-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-04
Career Henan Chemical Co
Product
3-BROMO-4-CHLOROANILINE 823-54-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

823-54-1, 3-BROMO-4-CHLOROANILINERelated Search:

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  • 3-BROMO-4-CHLOROANILINE
  • 3-Bromo-4-chlorobenzenamine
  • 3-Bromo-4-chlorophenylamine
  • BenzenaMine,3-broMo-4-chloro-
  • 3-Bromo-4-chloroaniline &gt
  • 823-54-1
  • Anilines, Amides & Amines
  • Bromine Compounds
  • Chlorine Compounds