IODIPAMIDE
- Product Name
- IODIPAMIDE
- CAS No.
- 606-17-7
- Chemical Name
- IODIPAMIDE
- Synonyms
- adipiodon;bilignost;IODIPAMIDE;ADIPIODONE;biligrafin;cholospect;transbilix;cholografin;iodipamicacid;Iodipamide (200 mg)
- CBNumber
- CB3125304
- Molecular Formula
- C20H14I6N2O6
- Formula Weight
- 1139.76
- MOL File
- 606-17-7.mol
IODIPAMIDE Property
- Melting point:
- 306-308°C (dec.)
- Boiling point:
- 908.6±65.0 °C(Predicted)
- Density
- 2.5848 (estimate)
- refractive index
- nD21.5 1.3294 (c = 0.445 in methanol)
- storage temp.
- Room Temperature
- solubility
- DMSO (Slightly), Methanol (Very Slightly)
- pka
- pKa 3.5(H2O) (Uncertain)
- color
- White
- Water Solubility
- 0.46g/L(20 ºC)
- Merck
- 5022
- EPA Substance Registry System
- Benzoic acid, 3,3'-[(1,6-dioxo-1,6-hexanediyl)diimino]bis[2,4,6-triiodo- (606-17-7)
Safety
- WGK Germany
- 3
- RTECS
- DG0949500
- HS Code
- 2924296000
- Hazardous Substances Data
- 606-17-7(Hazardous Substances Data)
- Toxicity
- LD50 in mice, rats (mg/kg): 2380 ±290, 4430 ±310 i.v. (Rosenberg)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 1343007
- Product name
- Iodipamide
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $358
- Updated
- 2024/03/01
- Product number
- PHR3188
- Product name
- Iodipamide
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 500MG
- Price
- $162
- Updated
- 2022/05/15
- Product number
- I0639
- Product name
- Iodipamide
- Purity
- analytical standard, for drug analysis
- Packaging
- 5g
- Price
- $72.9
- Updated
- 2022/05/15
- Product number
- I666800
- Product name
- Iodipamide
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FI24595
- Product name
- Iodipamide
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
IODIPAMIDE Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Originator
Cholografin,Squibb,US,1954
Uses
Diagnostic aid (radiopaque medium-cholecystographic).
Uses
antihypertensive, diuretic, activates K channels and AMPA receptors
Definition
ChEBI: Adipiodone is an organoiodine compound that is 3-amino-2,4,6-triiodobenzoic acid in which one of the amino hydrogens is substituted by a 6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl group. It is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography. It has a role as a radioopaque medium. It is an organoiodine compound, a member of benzoic acids and a secondary carboxamide. It is a conjugate acid of an adipiodone(2-).
Manufacturing Process
125 g of 2,4,6-triiodo-3-amino benzoic acid are dissolved in 250 cc of chlorobenzene and 15 g of adipic acid dichloride are added at a temperature between 110° and 130°C drop by drop to the solution. After evolution of hydrochloric acid (about 2 to 3 hours) has ceased, the precipitated crude adipic acid di-(3-carboxy-2,4,6-triiodo anilide) of the above formula is filtered hot with suction, washed with chlorobenzene, extracted by boiling with methanol and, for purification, dissolved in an amount of methanolic caustic soda solution required for neutralization, filtered with charcoal, and precipitated with dilute hydrochloric acid. Yield: 82.3 g, MP 306° to 308°C (with decomposition).
brand name
Pharmaceutic necessity for Iodipamide Meglumine [Injection]. Cholografin (Bristol-Myers Squibb).
Therapeutic Function
Diagnostic aid (radiopaque medium)
Hazard
Toxic by ingestion.
IODIPAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from IODIPAMIDE manufacturers
- Product
- IODIPAMIDE 606-17-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 0.999
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-13
- Product
- 3,3-Adipoyldiiminobis(2,4,6-Triiodobenzoic Acid) 606-17-7
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09