2-Iodobenzyl alcohol
- Product Name
- 2-Iodobenzyl alcohol
- CAS No.
- 5159-41-1
- Chemical Name
- 2-Iodobenzyl alcohol
- Synonyms
- 2-IodobenzyL;2-iodobenzenol;RARECHEM AL BD 0562;2-Iodophenylmethanol;O-IODOBENZYL ALCOHOL;2-IODOBENZYL ALCOHOL;2-Iodobenzenemethanol.;2-iodobenzylic alcohol;o-Iodobenzoyl Alcohol;2-IodobenzylAlcohol>
- CBNumber
- CB8373621
- Molecular Formula
- C7H7IO
- Formula Weight
- 234.03
- MOL File
- 5159-41-1.mol
2-Iodobenzyl alcohol Property
- Melting point:
- 89-92 °C (lit.)
- Boiling point:
- 145°C/10mmHg(lit.)
- Density
- 1.7904 (estimate)
- refractive index
- 1.6349
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Needle-Like Powder
- pka
- 14.01±0.10(Predicted)
- color
- White to yellow or pinkish
- Water Solubility
- Insoluble in water.
- Sensitive
- Light Sensitive
- BRN
- 2079487
- InChI
- InChI=1S/C7H7IO/c8-7-4-2-1-3-6(7)5-9/h1-4,9H,5H2
- InChIKey
- WZCXOBMFBKSSFA-UHFFFAOYSA-N
- SMILES
- C1(CO)=CC=CC=C1I
- CAS DataBase Reference
- 5159-41-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/38-36/37/38
- Safety Statements
- 22-24/25-37/39-26
- WGK Germany
- 3
- F
- 8-10
- HS Code
- 29062990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 183636
- Product name
- 2-Iodobenzyl alcohol
- Purity
- 98%
- Packaging
- 10g
- Price
- $82.36
- Updated
- 2025/07/31
- Product number
- 183636
- Product name
- 2-Iodobenzyl alcohol
- Purity
- 98%
- Packaging
- 50g
- Price
- $212
- Updated
- 2025/07/31
- Product number
- I0858
- Product name
- 2-Iodobenzyl Alcohol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- I0858
- Product name
- 2-Iodobenzyl Alcohol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $171
- Updated
- 2025/07/31
- Product number
- I737020
- Product name
- 2-Iodobenzyl alcohol
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
2-Iodobenzyl alcohol Chemical Properties,Usage,Production
Chemical Properties
white to yellow or pinkish needle-like powder
Uses
2-Iodobenzyl alcohol was used in the synthesis of substituted seven-membered lactones, 2-[(E)-(1?-iodo-2?-propenyl)]benzyl alcohol2 and 2,3-diphenyl-1-indenone.
Uses
2-Iodobenzyl alcohol was used in the synthesis of:
- substituted seven-membered lactones
- 2-[(E)-(1′-iodo-2′-propenyl)]benzyl alcohol
- 2,3-diphenyl-1-indenone
Synthesis Reference(s)
The Journal of Organic Chemistry, 39, p. 3052, 1974 DOI: 10.1021/jo00934a028
Synthesis
88-67-5
5159-41-1
The general procedure for the synthesis of 2-iodobenzyl alcohol from 2-iodobenzoic acid was as follows: to a tetrahydrofuran (THF) solution (16 mL) of commercially available o-iodobenzoic acid (4.15 g, 16.8 mmol) was slowly added borane-dimethyl sulfide complex (1.90 mL, 20.0 mmol) at 0 °C. The reaction mixture was stirred at room temperature for 15 hours before the reaction was quenched by the addition of phosphate buffer (pH 7). Subsequently, the reaction mixture was extracted three times with ethyl acetate and the organic phases were combined. The organic phase was washed with saturated brine and dried with anhydrous sodium sulfate. Concentration under reduced pressure to remove the solvent gave o-iodobenzyl alcohol (3.84 g, 98% yield) as a white solid, which could be used in the next reaction without further purification. The crude o-iodobenzyl alcohol (3.77 g, 16.1 mmol) was added to a dichloromethane (DCM, 33 mL) suspension of dimethyl sulfoxide (DMSO, 14.0 g, 161 mmol). The reaction mixture was stirred at room temperature for 30 h before being filtered through a diatomaceous earth pad, using dichloromethane as the eluent. The filtrate was concentrated under reduced pressure and the residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 5:1) to afford o-iodobenzaldehyde (3.36 g, 90% yield) as light yellow crystals.
References
[1] Chemistry - A European Journal, 2018, vol. 24, # 70, p. 18653 - 18657
[2] Tetrahedron Letters, 1987, vol. 28, # 2, p. 171 - 174
[3] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 15, p. 4669 - 4678
[4] Organic Letters, 2015, vol. 17, # 5, p. 1126 - 1129
[5] Journal of Fluorine Chemistry, 2015, vol. 179, p. 106 - 115
2-Iodobenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
2-Iodobenzyl alcohol Suppliers
- Tel
- 0512-65916026; 18015586221
- 2760994703@qq.com
- Country
- China
- ProdList
- 265
- Advantage
- 55
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 15883
- Advantage
- 64
View Lastest Price from 2-Iodobenzyl alcohol manufacturers
- Product
- (2-Iodophenyl)methanol 5159-41-1
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 2-Iodobenzyl alcohol 5159-41-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 2-Iodobenzyl alcohol 5159-41-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2019-08-29